One small step means giant leap for spinal cord research
... researchers have found that functional electrical stimulation (FES), a process that sends controlled bursts of electricity through the skin and into muscles, can help patients improve their step frequency, stride length and overall walking speed. "This is a group of patients in which recovery is not expected," ......of a co-ordinated linkage between the meal-related stimulation of protein synthesis and the inhibition of breakdown."...Study in Royal Society journal on link between creativity and mating success
...LE11 3TU Spatially resolved non-invasive chemical stimulation for modulation of signaling in reconstructed neuronal networks by Dr Y Mourzina, Mr A Steffen, Mr D Kaliaguine, Dr B Wolfrum, Dr P Shulte, Dr S Bcker-Meffert and Professor A Offenhusser A biohybrid system is created, in which networks of neuronal cel...Nutrient pollution causes a long-term effect on Chesapeake Bay ecosystem
...e organic content of 200 year-old sediment suggest stimulation of algae blooms during pre-industrial times. Lead author Dr. W. Michael Kemp, of the University of Maryland Center for Environmental Science, said "By studying long-term effects of nutrient enrichment and detailed processes by which coastal ecosys...JCI table of contents: November 23 2005
... effects. This strategy significantly improved the stimulation of tumor-specific T cell responses in these cancer patients, compared to vaccination alone. Researchers had previously suggested that eliminating this population of T cells could enhance the efficacy of cancer vaccines, and this study represents what...Turning sensation into perception
...archers used an electrode to apply weak electrical stimulation to MPC neurons. They found that stimulating these neurons made the monkeys more likely to respond that they perceived a vibration, whether the vibrating stimulus was occurring or not. Romo and de Lafuente also found that MPC neurons began to fire be...JCI table of contents November, 2005
...AT) as the sensor for fat. They show that lingual stimulation of CD36 by fatty acids influences behavioral and digestive physiology. CD36 gene inactivation fully abolishes both the spontaneous preference for fat and the changes in gastrointenstinal secretions mediated by oral delivery of lipids. These findings...Have a taste for fat? Yes! A sensor in the mouth promotes preference for fatty foods
...AT) as the sensor for fat. They show that lingual stimulation of CD36 by fatty acids influences behavioral and digestive physiology. CD36 gene inactivation fully abolishes both the spontaneous preference for fat and the changes in gastrointenstinal secretions mediated by oral delivery of lipids. These findings...JCI table of contents November, 2005
...AT) as the sensor for fat. They show that lingual stimulation of CD36 by fatty acids influences behavioral and digestive physiology. CD36 gene inactivation fully abolishes both the spontaneous preference for fat and the changes in gastrointenstinal secretions mediated by oral delivery of lipids. These findings...Where the brain combines what's heard and felt
...rong activation to particular impulses. A: tactile stimulation of the hand. B: auditory stimulation. C: simultane...e is strengthened when it is combined with tactile stimulation of a hand (see Image 2). Furthermore, the researchers found areas inside the auditory cortex that re...Mental stimulation through play has beneficial effect on children with stunted growth
Mental stimulation through play could improve IQ scores and reading i...ed at nutritional supplementation and psychosocial stimulation in a group of 129 stunted Jamaican children aged 9-24 months (Lancet 1991; 338: 1-5). The stimulatio...Stimulating the brain makes the fingers more sensitive
Repetitive transcranial magnetic stimulation (rTMS) has emerged as an intriguing technique for ...he finger, and then applied intermittent pulses of stimulation over the course of about ten minutes. They tested the sensitivity of the index finger by determini...Cyberkinetics, Case to develop system to help restore extremity function
...'s unique expertise in using functional electrical stimulation to restore meaningful arm and hand function to ind...r's body via a feedback method that can adjust the stimulation so that it accomplishes the desired movement. Some FES systems are currently available to consumers...JCI table of contents October 3, 2005
...gnaling mediated by ANP. The authors show that ANP stimulation leads to elevation of cGMP and nuclear accumulation of Akt, a cell survival protein. The accumulation of activated Akt in the nucleus correlates with translocation of zyxin, a cytoskeletal signaling molecule known to shuttle through the nucleus. Th...Study offers clues to origins of autoimmunity
... however, that self-reactive B cells need constant stimulation by their antigen to remain anergic, and that removing the antigen allows them to regain their normal, ready state. The researchers suggest that an active infection could draw a self-reactive B cell to a lymphoid organ, such as the tonsils or a lymph...Researchers: Deep sleep short-circuits brain's grid of connectivity
...alized on a new technology - transcranial magnetic stimulation - that permits precise, non-invasive activation of small regions of the brain. Subjects are also equipped with a cap of electrodes to monitor the brain's electrical activity so that the cell signals elicited by the quick bursts of electricity can be ...'Underground' tunnels discovered as means for communication between immune system cells
...t calcium flux, a well-recognized early measure of stimulation in numerous cell types. The use of a fluorescent dye, which allows direct measurement of calcium levels, would determine if calcium flux occurs before dendritic cells unfurl their veils. With a microinjection tip, they squirted a mixture of E. coli f...Key neural system at risk from fetal alcohol exposure
...may seek alcohol or drugs" as a substitute for the stimulation dopamine normally provides. For the monkeys exposed to alcohol during middle-to-late gestation, the effect was the opposite: "Animals exposed later had supersensitive (dopamine) receptors. If you have supersensitive receptors, you're more susceptible...Researchers zero in on estrogen's role in breast-cancer cell growth
...of the unwanted side effects of tamoxifen, such as stimulation of the uterus." In addition to Katzenellenbogen and Frasor, Jeanne M. Danes, a researcher in the department of molecular and integrative physiology, and doctoral student Cory C. Funk were co-authors of the study....Cancer drug target Chk1 may also be source of drug resistance
... target Chk1 for eventual destruction. Ironically, stimulation of Chk1 triggers certain repair responses that fight cancer while the simultaneous degradation of Chk1 can allow cancer cells to escape drug-induced death and resume progressive tumor growth. The study suggests the Chk1 protein is critical for ensur...