Fibromyalgia patients may benefit from cough remedy, UF study finds
... peg. The intensity of the heat or pressure of the stimulation was individually adjusted so that all participants... rate the amount of pain they experienced when the stimulation was repeated. With the heat stimulus, 90 milligrams of dextromethorphan reduced wind-up pain, but 60...Researchers observe predictors of natural immunity to ovarian cancer
... of antibodies found in the women studied requires stimulation of certain types of immune cells known as T-cells. Thus it is likely that multiple arms of the immune system may be activated during these events, and participate in the immune protection from cancer. Besides presenting a new model to explain risk...Mechanism for the captation of nutrients in plants- unknown to date
...ndocitosis would have to be encouraged through the stimulation of the genes involved in the formation of the vesicles a hypothesis that is currently being verified....... proteins that are activated in the liver upon CB1 stimulation are the same as those known to be activated in the brain and thus may be a common molecular target for metabolic regulation and appetite control. In an accompanying commentary, Aron Lichtman and Benjamin Cravatt write, "A particularly provocative im...Six previously blind patients detect light, motion, identify objects with retinal prostheses
... in perceptual acuity, "suggesting that electrical stimulation did not improve the health or function of the retina." Thus far, participants in the study have been people with little or no sight perception due to the degenerative eye disease retinitis pigmentosa (RP). Ultimately, however, the device is likely to...JCI table of contents May 2, 2005
... proteins that are activated in the liver upon CB1 stimulation are the same as those known to be activated in the brain and thus may be a common molecular target for metabolic regulation and appetite control. In an accompanying commentary, Aron Lichtman and Benjamin Cravatt write, "A particularly provocative im...Mouse with designer liver has enhanced glucose tolerance and improved insulin response
...hways critical to insulin response in cells. Upon stimulation with insulin, they found an elevated level of Akt/PkB kinase, an enzyme needed for insulin signaling, and elevated activity of IRS proteins. There was no activation of another enzyme, Erk, which is elevated in normal liver in reaction to insulin stim...Alcohol consumption disrupts breastfeeding hormones
...behave in tandem, such that sucking-induced breast stimulation results in transient release of both. However, following alcohol consumption we saw divergent responses in these two key hormones that control lactation." After consuming alcohol, women took longer to eject the first drop of milk and produced less mi...Ophthalmologists and physicists team up to design 'bionic eye'
...omputer. Physical limitations regarding electrical stimulation most likely make it impossible for implants to imp...sed into pores, which localizes currents and makes stimulation selective, perhaps allowing researchers to stimulate single cells. Huie, a cell biologist and histol...Quality of mom's time, not quantity, most important in early infant development
...ve to their babies' needs and to provide cognitive stimulation to their children. Aletha C. Huston, PhD, and Stacey Rosenkrantz Aronson, PhD, analyzed 24-hour diaries of time use from 1,053 mothers of infants collected in the National Institute of Child Health and Human Development Study of Early Child Care....Surprisingly complex behaviors appear to be 'hard-wired' in the primate brain
... at Princeton University pointed out that previous stimulation experiments in the motor cortex the area that controls bodily motions had been done using very short electrical pulses that last less than a half-second. He further suggested that longer pulses might stimulate more complicated motions. Working with...A new route for treatment of IBD
...is due to defective induction of type I IFN by TLR stimulation in mice of this genotype. Further, they show that the inability of SCID to produce IFN is due to a mutation that impairs TLR9 signaling in this strain. Thus, type I IFN has a protective role in colon injury and protects against colonic inflammation. ...JCI table of contents March 1, 2005
...is due to defective induction of type I IFN by TLR stimulation in mice of this genotype. Further, they show that the inability of SCID to produce IFN is due to a mutation that impairs TLR9 signaling in this strain. Thus, type I IFN has a protective role in colon injury and protects against colonic inflammation. ...Source of molecular triggers in cutaneous T cell lymphoma identified
... LC." The study also showed that CTCL cells, after stimulation by LC, become functioning regulatory T (Treg) cells that suppress the immune responses of normal T cells to microbial agents. This may explain the susceptibility of patients with extensive CTCL to opportunistic infections. "Through understanding T c...Alcohol's effects on gene expression in the central nervous system
... by increased formation of synaptic proteins. The stimulation of VTA dopamine neurons by alcohol increases the expression of genes involved in the synthesis of synaptic proteins in target regions of the VTA. In short, these results suggest that alcohol can produce changes in the brain reward system that can fu...Wnt signalling protein Dishevelled acts in the nucleus, not just in the cytoplasm
...iliser of beta-catenin in the cell cytoplasm after stimulation by Wnt secreted ligands binding to Frizzled receptors on the cell surface. Sokol and colleagues show using Xenopus embryos and mammalian cultured cells that a mutated version of Dsh, which accumulates in the nucleus, is functional in the Wnt signall...Bird brains show how trial and error may contribute to learning
...ale mating song can be permanently altered by LMAN stimulation and whether females prefer the stable or variable song version.......n granules onto the plasma membrane during glucose stimulation AUTHOR CONTACT: Tetsuro Izumi Gunma University, Gunma, Japan. Phone: 81-27-220-8856; Fax: 81-27-220-8860; E-mail: tizumi@showa.gunma-u.ac.jp This article is available at http://www.jci.org/cgi/content/full/115/2/388 . ACCOMPANYING COMMENTARY: TITL...Gene with broad role also causes prevalent, inherited nerve disorder
...g defect in CMT is muscle atrophy due to a lack of stimulation from the nerves. That lack of stimulation stems from one of two underlying causes, which define the two primary forms of the disease: CMT type...Green tea extract boosts exercise endurance 8-24%, utilizing fat as energy source
...rance capacity and support the hypothesis that the stimulation of fatty acid utilization is a promising strategy ...tabolism. Our results support the hypothesis that stimulation of lipid metabolism is a promising strategy for improving the capacity for endurance training." The ...