New research may explain why some who receive growth hormone therapy develop colon polyps
...ivo, in laboratory animals, with a focus on how it stops the action of cellular growth hormone." The researchers thought an ideal way to study this issue would be to use an animal model of acromegaly, laboratory mice having excessive amounts of growth hormone. The animals were crossed with animals in whic...Ginger causes ovarian cancer cells to die, U-M researchers find
...ory reaction, the researchers suspect, ginger also stops cancer cells from growing. "In multiple ovarian cancer cell lines, we found that ginger induced cell death at a similar or better rate than the platinum-based chemotherapy drugs typically used to treat ovarian cancer," says Jennifer Rhode, M.D., a g...Researchers reverse juvenile diabetes in animal model; Clinical trial FDA approved
...ks the beta cells, but the result is that the body stops producing insulin. When that happens, glucose builds up in the blood, but the body's cells starve to death. "We are very excited to begin the clinical trials and see if this process will work in patients with type 1 diabetes," said Dr. Trucco. "A typ...Einstein researchers find potential new drugs for tuberculosis
...rugs." Isoniazid, today's first-line anti-TB drug, stops TB bacteria from forming mycolic acid, a key building block for their cell walls. It does the job by targeting an enzyme called InhA. Trying to improve upon isoniazid, the Einstein researchers synthesized more than a dozen chemical "decoys" for InhA ...Infection 'alarm' yields clues to immune system behavior
...mune response, a localized reaction which normally stops an infection threat confined to a small part of the body, such as in the case of a pricked finger. (This is in contrast to a systemic response that triggers an immune reaction throughout the body, causing a fever. If the immune system responds too ag...Horseshoe crab decline threatens shorebird species
...rd. And each year from April to June, the red knot stops over in the Delaware Bay to feed on horseshoe crab eggs resulting from the largest spawning of horseshoe crabs found on the East Coast of the United States. Researchers from Virginia Tech and the New Jersey Division of Fish and Wildlife have documen...Plant enzyme efficiency may hold key to global warming
...ive. RuBisCOs inefficiency limits plant growth and stops organisms from using and assimilating all the carbon dioxide in the atmosphere, even as the amount of gas in the atmosphere con-tinues to grow. The resulting gas buildup is one cause of global warming. A 2004 report by the National Science Foundati...Finding life on Mars and outer space begins by examining Earth's inner space
...ono Lake is one of the most popular migratory bird stops in the West, all sustained by microbes. And the way the microbiology of Mono Lake interacts with salt deposition, it's also a great place for capturing and preserving fossil signatures of microbial life," said Farmer. The research is part of The JA...WHSRN announces three new international sites
...d South America. On its return visit, the species stops at Anahuac where the highest count on a single day has been 2,200 birds more than 10 percent of its total population. The new WHSRN coalition sites will help protect migratory shorebirds that face environmental and other threats to their survival. ...UCLA scientists uncover mechanism of response to targeted therapy
...h other therapies because it "in kidney cancer, it stops the tumor cells from growing, it doesn't kill them." It could be paired with conventional chemotherapy or with another targeted therapy, such as an angiogenesis inhibitor, which cuts off the independent blood supply that cancers need to grow and flou...Tumor cells that border normal tissue are told to leave
...e genes in the pathway activated in boundary cells stops the cells from leaving the tumor. Cagan's laboratory also has developed a robotic system for screening anticancer drugs, and they plan to use this system to look for drugs that will affect the metastatic process in their fruit fly model. "A drug th...Other highlights in the January 4 JNCI
... human brain cancers. The drug temozolomide, which stops tumor growth by preventing DNA replication in the cell, was approved in 2005 for the treatment of glioblastoma, a rapidly fatal type of brain cancer. However, some glioblastomas do not completely respond to this drug because the cancer cells repair D...Researchers publish the dog genome sequence
...complimentary trolley ride from the MBTA JFK/UMASS stops at Bayside.Url: http://www.baysideexpo.com...The end of aging? New study examines evolutionary explanations for 'biological immortality'
...ines the point in human life when your body simply stops aging. "For decades, demographers and gerontologists noticed that late life human data did not fit [expected] models: there was a shortage of deaths," write Michael R. Rose, Casandra L. Rauser, and Laurence D. Mueller. "More specifically, the expone...Figuring out the ups and downsand sidewaysof neural development
...cing one proliferating progenitor and another that stops proliferating and differentiates into an adult neural cell. And during final brain development, the cells return to symmetric cell division, creating differentiated adult cells. The two types of cell division seem to be governed by the orientation of...Plants have a double line of defence
...esistance. Although, in nature, nonhost resistance stops almost all parasite attacks, it has been the subject of little research. Scientists from the Max Planck Institute for Plant Breeding Research in Cologne, working with Volker Lipka, Jan Dittgen, and Paul Schulze-Lefert, and in co-operation with colle...Innovative research set to push boundaries of cancer care
...at induces apoptosis in cancer cells. P53 normally stops cells that are damaged from reproducing and encourages them to commit apoptosis, but a majority of cancer cells have damaged or missing p53. To test the therapeutic power of azurin to damage cancer cells, the researchers have used it in mouse models...Combination therapy for mouse model of human inherited blindness
...set of these diseases, it is known that the retina stops functioning due to loss of the lecithin retinol acyl-transferase enzyme (LRAT). LRAT is required for regeneration of a pigment necessary for the eye to detect light. LCA can be caused by mutations in the gene encoding RPE65, a key protein involved in...A persistent immune response to an acute viral infection
...ause severe aplastic anemia, where the bone marrow stops making blood completely for a time. In a normal person, parvovirus B19 infection is often asymptomatic but can result in long-term arthritis. In pregnant women, it can cause intrauterine fetal death. The team of researchers from the Karolinska Instit...When do mosquitoes prefer a blood banquet, or a sugar feast? Three genes make the call
...ody causes the virus to go dormant, too. The virus stops replicating, then starts replicating again in the spring when the mosquito leaves dormancy." Whether scientists could use this information to manipulate mosquito populations to control the spread of West Nile will take years to find out, he added....