UCF researcher uncovers protein that could stop replication of cancer cells
...ntil eventually they become so small that the cell stops multiplying. Eventually the cell is eliminated from the body. When telomere ends do not shorten, division continues unabated. The body contains other mechanisms that kick in to stop the errant reproduction unless the telomerase enzyme is present. I...Master gene controls healing of 'skin' in fruit flies and mammals
...nts out that very little is known how wound tissue stops its growth behavior when the wound is healed. In addition, cancer cells evade this "stop" program, but how they do it is not well understood....Gladstone investigators discover how resting T cells avoid HIV infection
...the small, enzymatically active form of A3G, which stops the virus in its tracks." CD4 T cells are a class of lymphocytes, or white blood cells, that fight infection by orchestrating immune responses. They have the ability to recognize specific antigens -- foreign substances, such as toxins, bacteria or en...Alcohol consumption disrupts breastfeeding hormones
...drinks occasionally can wait a few hours after she stops drinking to breastfeed so that her infant is not exposed to the alcohol in her milk. However, she needs to be aware that the hormones underlying lactation and her milk production will be affected in the short term."...Molecular testing impact: Heart transplant patients benefit from new technology, easier monitoring
...art as if it were a foreign object until the organ stops functioning properly. As a result of this risk, patients generally endure multiple cardiac biopsies, as many as 12 sometimes more in their first year after a transplant; periodic biopsies may continue for years. Unfortunately for many patients, bio...U of T researchers map role of Epstein-Barr virus in cancer
... problems in the cell such as damaged DNA and this stops the cell from proliferating. Through binding USP7, EBNA1 keeps the p53 levels low so cells will continue to divide when they shouldn't, which means they're now more likely to develop into cancer," Frappier says. "All viruses known to be able to cause...Natural tumor suppressor in body discovered by UCSD medical researchers
...tional laboratory tests, the team found that PHLPP stops tumor growth by deleting a specific phosphate molecule at a position called Ser473 on Akt. The scientists noted that PHLPP's role as a tumor suppressor would apply to all cancers where Akt is elevated, "which is a large number of cancers," Newton sai...BRCA1 causes ovarian cancer through indirect, biochemical route
...osa cells normally give off a chemical signal that stops the epithelial cells from growing out of control. When that chemical signal disappears or is muted by a mutation in the BRCA1 gene, the epithelial cells don't get the message, and keep on growing and dividing. The result: ovarian cancer. This finding...Vital step in cellular migration described by UCSD medical researchers
... as leukocytes move toward targets, a therapy that stops that movement could potentially help in autoimmune disorders where the body's immune system incorrectly attacks the body's own tissue." From the genesis of human life to birth and beyond, cell migration is a complex, extremely important process that ...Temple University researchers develop new targeted cancer therapy
...e unique actions of ON01910, Reddy said, "Our drug stops tumor cells from reaching normal cells three ways. First, it blocks invasion, next it blocks angiogenesis and finally, it induces tumor cell death. It also appears to be very safe." Other research team members are Kiranmai Gumireddy1, M.V. Ramana Red...Compound from rare plant shows promise in treating breast cancer
...ompound, derived from a rare South American plant, stops the growth of human breast cancer cells in laboratory cultures. U. Va. Health System scientists Deborah Lannigan and Jeffrey Smith hope that, after further testing, their discovery could translate into a successful drug for the treatment of...New puzzle-piece shows how growth hormones work in plants
...d brassinosteriod-response element or BRRE), which stops the process of transcription--the transfer of gene...n enzyme needed for BR synthesis, this suppression stops the production of BR conferring a feedback regulation of BR production. When the BR steroid level is...How do cells travel through our bodies?
...at happens in a strain of mouse in which n-cofilin stops functioning at the time the neural crest forms. They found that the edges of the curl cannot move together and fuse, so the head and spine remain open. This closely resembles Spina bifida, a condition that leads to severe disabilities in humans and i...Combination therapy boosts effectiveness of telomere-directed cancer cell death
...cell division no longer work properly and the cell stops dividing. In a sense, telomeres function as a kind of counting mechanism that regulates how many times a cell can divide. In contrast to normal cells, cancer cells divide continuously and uncontrollably. Scientists know that cancer cells produce an e...Scientists find that the human nose is more complicated than a jumbo jet
Winter colds can give you a blocked up nose that stops you smelling chimney smoke, roasting chestnuts, warming winter puddings and the other seasonal scents. Now researchers funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have not only discovered how air moves through the nos...Fox Chase Cancer Center scientists discover key proteins linked to aging and cancer
...iation is the process whereby a proliferating cell stops growing and develops into a cell with a specific function, such as a liver cell or a neuron. Senescence is an irreversible stage in a cell's life cycle and may underlie the human aging process and have an impact on diseases of aging, such as adult c...Psychological stress and disease: UCSF-led study suggests connection
...ch telomeric DNA has diminished that the aged cell stops dividing. Thus, telomeres play a critical role in determining the number of times a cell divides, its health, and its life span. These factors, in turn, affect the health of the tissues that cells form. Telomerase is an enzyme that replenishes a port...Growth factors confer immortality to sperm-generating stem cells
...stem cells. Whereas the female germ cell, the egg, stops dividing before birth, the spermatogonial stem cells continue to divide throughout life. According to Brinster, it is possible to modify the male germ line between generations by manipulating the spermatogonial stem cells in culture. "If each pare...Study describes basic mechanism in cell growth control involving damaged DNA
... suppressor protein p53," said Xiong. This protein stops the cell from growing or kills it, he added. "If the cell is growing happily, it would not want p53 around. So it places ubiquitin on it, slating it for degradation, for recycling when it's needed." In their current report, Xiong and UNC co-authors J......h the material to cool the wearer. When the wearer stops sweating, the spikes will close down again to stop air getting in. The lower layer will be of material that is not porous so that rain can never get through from the outside, whether the spikes are open or closed. The technology of the material is be...