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New culture method for hepatitis C virus uses primary hepatocytes and patient serum

...rmed hepatocytes, instead of culture-adapted virus strains in transformed cell lines. The related report by ...hen sera from patients infected with different HCV strains were added to the hepatocyte culture system, viral replication occurred and new virus particles were...

Cypress replanting unsuccessful without dual cultivation with lavender or mycorrhizal fungi

...glasshouse experiments, the researchers inoculated strains of these fungi, sampled from the study zones in the Moroccan High Atlas, into young nursery plants. There resulted a distinct improvement in the development of these young cypress with inoculated mycorrhizal fungi, which had a higher level of mineral...

The new form of trypanosomiasis discovered in India stems from a deficiency in apolipoproteinL-1

...mplete absence of any trypanolytic activity on two strains of T. evansi, but also on T. b. brucei. Conversely, these same strains were destroyed on contact with normal serum. The APOL-1 protein, responsible for the trypanolytic ac...

Tracing the pathways of neurofibromatosis

...periments, they created more than two dozen mutant strains of fruit flies, including varieties that were eith...tant strain were examined. By comparing the mutant strains each with a specific defect or set of defects they buillt a case that the absence of neurofibromin...

UCLA and NYU microbiologists crack genome of a parasite that causes a common STD

...n the United States, and the emergence of parasite strains that are resistant to these drugs is on the rise. There is a clear need to develop additional effective drugs, Johnson said. The T. vaginalis genome project began in 2002 and was funded by the National Institute of Allergy and Infectious Diseases, ...

All in the family

...searchers found that those men who carried certain strains of the bacterium in their stomachs and came from families of seven or more siblings were more than twice as likely to develop stomach cancer compared to carriers who had one to three brothers and sisters. The findings are reported January 16,...

Leading cause of US food-borne illness makes its own pathway through cells

...d expanding the work to include studies in special strains of mice that are infected by, and harbor the bacteria but do not show the acute symptoms of infection....

Wheat can fatally starve insect predators

...esistant to Hessian fly invasions may make several strains of lectins in response to virulent larvae, Williams said. Results of the study are published in the January issue of the journal Molecular Plant Pathology. Researchers also discovered that not only do lectins damage the insect's mid-stomach, the ...

Tumor-suppressor gene is critical for placenta development

... placed in the Rb gene. When she crossed the two strains of mice, the resulting embryos had the DNA-destroying enzyme and the gene markers in their placenta stem cells. The enzyme removed the DNA between the two markers, leaving the embryos without a working Rb gene in the placental progenitor cells. The...

Annual plants may cope with global warming better than long-living species

...pecies. Bennett and his colleagues froze ancestral strains of E. coli so they could evaluate the bacterium's adaptive evolution after culturing it at elevated temperatures for thousands of generations. Today, Weis is the organizing chairman of Project Baseline, a national effort to collect and preserve seed...

Genetically altered cells may help artificial skin fight infection

...also contribute to the emergence of drug-resistant strains of bacteria. "When you give the patient the same drug topically and orally, the risk for drug-resistant bacteria to emerge is greatly increased," says Supp. "We need alternative methods for combating infection in burn patients. In this three-ye...

New HIV test may predict drug resistance

...ensitive test for identifying which drug-resistant strains of HIV are harbored in a patient's bloodstream. T... the virus in their bodies. In some cases, mutated strains take on new properties that make them more resistant to the drugs used in antiretroviral therapy, th...

Getting to the bottom of memory

...memory. Using genetic methods they generated mouse strains with a defective version of a receptor molecule called TrkB. TrkB is found on the surface of cells in the hippocampus, an area of the brain involved in memory formation, and translates incoming signals into cellular responses. Mice with the defective...

Study finds surfing safer than soccer

...isit, or required on-site suturing. "Sprains and strains to the lower extremities, particularly the knees, were found to be the most common injuries reported. This is likely due to the aggressive turning and aerial maneuvers, which score highly in competitions, but also appear to place high stress on a sur...

Synthetic peptide targets latent papilloma virus infections

...ll. Many of the 90-plus known genetic variants or strains of HPV cause warts in surface tissues, including t...isms, says that such a drug might work against all strains of HPV because the E2 tethering protein is similar in all the viruses. And because the E2 protein is...

LIAI completes world's most comprehensive analysis on influenza virus data

...most of the current influenza research is based on strains maintained in the lab, rather than wild influenza ...mutates, research needs to be done using influenza strains currently circulating in the population, so-called 'wild' strains, rather than using strains propaga...

Screening for complex genetic interactions

...proach, the researchers culled through nearly 5000 strains of yeast to identify over 200 genes that interact with actin. This paper is one of the first examples of a large-scale CHI screen, and it is expected that this kind of systemic analysis will be particularly useful in uncovering complex genetic intera...

Cluster of journals publish findings on dangerous parasite, Toxoplasma gondii

...in of "Toxoplasma" especially dangerous. "Type I strains are extremely important to human medicine as they are disproportionately responsible for inflammation of the brain in AIDS patients and for severe congenital disease that is passed from mother to baby," White said. MSU led the study that was publis...

University of Colorado influenza chip licensed by Quidel Corp. of San Diego

...determine the genetic makeup of specific influenza strains from patient samples within hours. Current methods take about four days. Identifying flu strains is critical for tracking emerging strains and helping world health officials combat coming epidemics...

Plant biologist seeks molecular differences between rice and its mimic

...d species and the wild species occur. These weedy strains then took hold in U.S. soils and began contaminating the U.S. cultivated species. Meet the candidates Olsen says that the weed has many characteristics of a wild species. "By looking at candidate genes and those genes surround...

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(Date:11/19/2009)...urring brain chemical with an unwieldy name: 4-hyd...sed or used as a date-rape drug. , Now, a team ...w routes by which 4-HB is metabolized by the body....Michael Gibson, professor and chair of biological ...a member of the research team. "It may provide ne...
(Date:11/19/2009)...n, 1 + 1 = more than 2: The offspring of two inbre...ents. Characterizing the gene-level variability th... hybrid vigor, could boost our ability to custom-t...ein content for human consumption or high glucose ...newly released DNA sequence of the common corn str...
(Date:11/19/2009)...v. 19, 2009 -- Sustainable farming, initially adop...s, may also play a role in maintaining a healthy c... of Energy,s Oak Ridge and Los Alamos national lab...ing the large potential of the earth,s soils to se...and-use practices could greatly reduce U.S. carbon...
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