Male contraception: One door opens, another closes
...n is somehow different. He has now tested multiple strains of mice and found some effect, but not enough to produce infertility. "Biology is full of surprises. Clearly in the case of miglustat, a man is not a mouse," he adds. Next? So with Adjudin showing positive results--but in rats--and miglustat...Bacteria in small sea life yield new way to make potential cancer drugs
...se genes to make small molecules within laboratory strains of bacteria. This genetic synthesis method is complicated because it's still difficult to understand how changing genes can lead to changes in small drug molecules. "The promise of genes is that you can access the tremendous natural diversity of th...Novel experiment documents evolution of genome in near-real time
...ial potential, experimental evolution of bacterial strains is also useful for refining the theory of evolution and the related process of natural selection of individuals with traits that convey a selective survival advantage. "Opinion surveys indicate that many people don't believe that evolution occurs," s...Your genes may hold key to how sick you get from the flu
...s some, not others Trammell and Toth infected two strains of laboratory mice with an Influenza A virus. Our ...ou give the same dose of influenza A virus to both strains of mice, about half of the BALB/cByJ (Type B) mice will die, compared to about 10% of the C57BL/6J (...Spin-out company seeks medicines from South American rain forests
...to reach pandemic levels, including drug-resistant strains of tuberculosis and virus infections like avian flu. New drugs are also being sought for tropical diseases which occur in Brazil, such as hepatitis C, Chagas disease and Leishmaniasis. In a separate deal, e-Therapeutics is joining forces with CURA, ...ASU researchers test antibacterial effects of healing clays
...microbiologist," Haydel says. "I ordered bacterial strains that pharmaceutical companies use to test their antimicrobials." Haydel and Williams tested both of the French clays that Brunet de Courssou had been importing. One completely inhibited pathogenic Escherichia coli, Salmonella typhimurium, Pseudomon...MRSA vaccine shows promise in mouse study
...mals from multiple disease-causing, drug-resistant strains of Staphylococcus aureus, the most common cause of...cademy of Sciences, available early online. These strains include USA100, a common cause of hospital-acquired infections, and USA400, a virulent community-ass...Scientists discover two-component lantibiotic with therapeutic potential
...ions. The rapid spread of drug-resistant bacterial strains poses a persistent threat to human health, and req...ed lacticin 481, a lantibiotic produced by several strains of Lactococcus lactis, a bacterium used in cheese production. In March 2006, van der Donk's team rep...New study has important implications for flu surveillance
...nitoring changes to the virus and predicting which strains should be used for flu vaccine. The study, which w...presentative collection of the two most common flu strains (called H3N2 and H1N1) from the 1995-2005 flu seasons in New York state and New Zealand. The sequenc...New behavior may use old genes
... accomplished this by first breeding two different strains of bees that exhibit starkly different foraging be...involving pollen-favoring strains, nectar-favoring strains and their hybrids, behavior differences in the resulting worker offspring were linked to genetic var...Mouse DNA to aid biomedical research
... have successfully resequenced the DNA of 15 mouse strains most commonly used in biomedical research. More t... were discovered among the genomes of the 15 mouse strains and the data are now publicly available. These new data will help researchers better understand com...Viral marker of human migration suspect
...Disease Dynamics. "But, in the case of this virus, strains from European communities appear to be the most divergent." The human polyomavirus, or JCV, is a small double-stranded DNA virus that is thought to be primarily transmitted from parents to their children. Infection is usually asymptomatic unless a ...Molecule discovered to be key to pain sensitivity
...evious studies in animals have shown that specific strains or related groups of rodents have significant differences in their risk of developing either neuropathic pain, which results from nerve damage, or inflammatory pain, associated with the immune system's response to injuries or conditions like arthriti...Tips from the journals of the American Society for Microbiology
...rchers have identified common virulence factors in strains of Escherichia coli collected from infected humans...the Journal of Clinical Microbiology. Pathogenic strains of E. coli O18:K1:H7 (ExPEC) are implicated in a range of infections in humans such as neonatal meni...Potassium limitation, ammonium toxicity and amino acid excretion in yeast
...specific to ammonium. Tests across different yeast strains found this to be not a quirk on one strain of S. cerevisiae. Further as a metabolic fingerprint of this adverse reaction to ammonium, the researchers observed high levels of amino acids in the cellular environment of these potassium-limited cells, as...HIV exploits competition among T cells
...tition, immunodominance, occurs when several viral strains simultaneously infect one person. In this case, T ...to go with those cells when it's confronted by new strains of the same disease in the future," Deem said. "For HIV, which mutates rapidly, this is an Achilles'...Friendly bacteria in alcoholic milkshake could fight food allergies
...e can screen out the certain components (bacterial strains or bioactive peptides) from kefir and utilize them in medicine," he said. Also in this weeks Chemistry & Industry, UK firm Rigest are looking for backers to develop an air sanitizing system using an enzyme found naturally in human tears. Lactoperox...Forsyth scientists find linkages between serotonin reuptake inhibitors and bone mass
...ride (LPS), a component of the membrane of certain strains of bacteria, resulted in an increased number of osteoclasts and net bone loss. However, LPS given with fluoxetine caused new bone formation and a net gain in bone mass. The study concluded that fluoxetine treatment in vivo leads to increased bone m......e with resistance to this agent. The proportion of strains of mutant Plasmodium in the samples is thus a dire...ently conducted. The frequency of mutant resistant strains and the number of mutations were plotted for the different areas. The data obtained, such as the low...