Tag: "strands" at biology news
Molecule that helps DNA replicate may make good target for cancer therapy
...luding a large enzyme complex that synthesizes new strands
of DNA. In a paper to be published Oct. 22 in the ... itself: Before DNA replication can begin, the two strands
in the DNA double helix must be unwound. Next, multiple molecules of a certain protein attach to the...
JCI table of contents, November 15 2004
...ing ultrafiltration membrane. TITLE: Nephrin strands
contribute to a porous slit diaphragm scaffold as revealed by electron tomography. AUTHOR CONTACT:Karl Tryggvason Department of Medical Biochemistry and Biophysics, Karolinksa Institute, Stockholm, Sweden. Phone: 46-8-7287720; Fax: 46-8-316165; E-m...
USC-led team of scientists recreates DNA-mending pathway in test-tube
... purify all the proteins used to rejoin the double strands
of DNA once they've suffered damage and are severed from one another. As it turned out, two of the seven proteins come from a class of polymerases that were discovered in 1999 by Myron Goodman, Ph.D., professor of molecular biology at the USC College...
Discovery of first demethylase molecule, a long-sought gene regulator
...ethylation is no different." In the cell, yarnlike strands
of DNA wrap around protein scaffolds built of histones. The histones organize DNA into a packed structure that can fit into the nucleus, and the packing determines whether the genes are available to be read or not. Acetyl, methyl, or other chemical t...
NYU chemists create DNA translation machine
..., known as DX molecules, as an adapter between the strands
they carry and the device. The researchers tested ...olution. The intended DX molecules, which included strands
from the target product attached to the device, and the target strands
were bonded together, thereby...
Needling chromosomes yields insights into cell division
...e some entanglements between the corresponding DNA strands
on each chromatid. DNA, which makes up genes in the cell, replicates itself as a central process in chromosome duplication. "So, we're left with the mystery of what molecules hold the chromatids together at this point in cell division," Nicklas said....
DNA molecules used to assemble nanoparticles
...d DNA molecules, which naturally bind to other DNA strands
in a highly specific fashion. "With this approach, you can target a wide variety of molecules---drugs, contrast agents---to almost any cell," said Dr. James R. Baker Jr., the Ruth Dow Doan Professor of Nanotechnology and director of the Center for B...
Study in Royal Society journal on sense of fairness in chimpanzees
...ocess is achieved by the separation of the two DNA strands
forming large bubbles, called transcription bubbles. Some molecules, called enzymes, are able to produce small bubbles. Using computers it is possible to simulate their evolution at different temperatures. At very low ones the small bubbles remain st...
Sequencing of marine bacterium will help study of cell communication
...ith 'C'. The more GC content, the more tightly DNA strands
bind.) Despite the fact that it is a symbiont, V. fischer's genome contains genes that may have toxin activity. "Analysis of this sequence has revealed surprising parallels with Vibrio cholerae and other pathogens," said Ann Stevens, associate profes...
Time to rewrite the species rulebook, MSU scientists say
...lit in two, for instance by heating it up, its two strands
will spontaneously find each other, or reassociate...g just what makes up a species of bacteria. Single strands
of DNA from two bacteria are mixed together. If most of these strands
reassociate specifically, if ...
Biochemists report discovery of structure of major piece of telomerase; implications for cancer
...uired for telomerase activity, at whose core three strands
of RNA come together to form a triple helix. All vertebrate animals investigated so far have nearly the identical sequence of nucleotides through the triple helix, Theimer said. "The triple helical structure of the pseudoknot must be significant sinc...
Silence the gene, save the cell: RNA interference as promising therapy for ALS
... (mice bred to express the human SOD1 gene). Short strands
of RNA that targeted multiple mutated and normal forms of the human SOD1 gene were delivered in a specially engineered lentivirus. Expression of the SOD1 protein was knocked down in the affected motor neurons and neighboring glial cells, and both the...
Researchers rein in regulatory RNAs
...pairs of RNA molecules generated from opposite DNA strands
at the same locus. The number of SATs identified in the past several years has grown substantially, and they are now believed to comprise at least 8% of human genes. Many SAT pairs have been implicated in various stages of gene regulation, includin...
Researchers devise way to mass-produce embryonic stem cells
... grow stem cells while other stem cells grew upon strands
of polymer threads inside a bioreactor. The bioreactor used in this study is a tissue-growing device developed by Ohio State scientists. While this bioreactor could be used to produce adult stem cells, the researchers chose to look solely at embryoni...
Children's Hospital & Research Ctr. at Oakland's DNA library helps to map the sex chromosome
...ter at Oakland's DNA library was used to duplicate strands
of DNA for an international team of scientists to ...uses harmless bacteria to make many copies of long strands
of fragile DNA. The DNA must be stabilized before it can be introduced into the bacterial cells. On...
Nanotechnology's progress and challenges addressed during ACS meeting
...agnetic particles and gold nanocrystals laced with strands
of DNA, referred to as bar code DNA. Somewhat like a consumer bar code, these DNA barcodes are identified on a chip designed to sort and measure their concentrations. The assay also holds promise for detecting HIV, cancer and heart problems. It could...
Researchers pioneer new gene therapy technique using natural repair process
...nation is a fairly rare event that occurs when DNA strands
of one chromosome break, creating a damaged section. Cells have two copies of nearly every chromosome (one each from the mother and father) and they must duplicate these during cell division so that the subsequent cells will also have two each. The w...
Method shows how precisely gene expression signals are copied in DNA replication
... introduced a molecular method to look at both DNA strands
together and observe methylation differences between them. "When we look at both DNA strands, we know one strand has to be the parent and one has to be the daughter, but we don't know which is which," Miner said. "The new mathematical model allows u...
Embryonic law and order
...fly protein named HOW, and it works by "arresting" strands
of RNA on their way to manufacture a second protein. Levels of the second protein, known as Cdc25, regulate the timing of cell division, and its production is ultimately controlled by yet another protein, Twist, which sets the process in motion. In t...
Ancient immune defense mechanism is no match for HIV-1
...ed by a protein called Dicer, which chops the long strands
of RNA into smaller pieces, resulting in the production of an RNA-induced silencing complex (RISC). RISC can specifically identify and degrade complementary target RNA. This process is known as RNA interference (RNAi) and can silence the ability of...
1 2 3 4 5 6 7 8