Insulin sensitizer also serves as energy-conserving signal to the brain
...cal in the brain may represent a novel therapeutic strategy for obesity and obesity-linked diseases, he added. White adipose tissue (WAT) is a major site of energy storage and plays an important role in energy balance, the researchers said. It is also recognized as an important endocrine organ that secrete...MIT, BU team builds viruses to combat harmful 'biofilms'
...c biofilms. As a proof of concept, they used their strategy to engineer T7, an Escherichia coli-specific phage...phage's nonengineered cousin. The team's modular strategy can be thought of as a plug and play library, says Collins. The library could contain different phag...Biocontrol of invasive water hyacinth contributes to socioeconomic and health improvements in Africa
...m that rid Lake Victoria of the weed. The control strategy integrated mechanical removal and use of two insects that are natural enemies of the weed--weevils in the genus Neochetina--N. bruchi and N. eichhorniae, both natives of South America. Dr. Ogwangs work on the Lake Victoria water hyacinth eradicati...Coaching computer canines in clambering
...aware of the location of its center of gravity.The strategy for walking, as explained in a paper Schaal presented at the 2007 IEEE International Conference on Robotics and Automation, was "to adjust a smooth walking pattern generator with the selection of every foot placement such that the center of gravity ...NIEHS researchers identify enzyme critical in DNA replication
...University. The researchers used an innovative strategy to demonstrate that in bakers yeast, DNA polymeras...logy at NIEHS. Kunkel explained that the general strategy used in the study can now be applied to investigate other reactions that are critical for genome sta...Tracing Parkinson's lethal mechanism
...her than Cdk5 directly may be a better therapeutic strategy with regard to this pathway. ......nt will increase the efficacy, as would using this strategy in combination with other treatments, Altaner said. Normal mesenchymal cells can be isolated from various sources, including bone marrow, but the yield is not nearly as great as what the researchers derived from fat tissue. Removal of fat tissue d...Scientific American launches innovative new version of magazine
... redesigned publication is part of a broader brand strategy by parent Holtzbrinck Publishers which also owns trade book publishers St. Martin's Press and Farrar, Straus and Giroux, stressing interactivity and integrated platforms. Scientific Americans website already offers podcasts, video and blogs, as well...Skin rash actually signifies better outcomes for pancreatic and lung cancer patients
...k to their doctor about an effective and proactive strategy to manage the rash while continuing Tarceva therapy. According to the researchers, these rashes can be controlled with mild steroids or antibiotics, and in most cases, they will improve with treatment. They are believed to be due to an inflammatory...Key to tackling malaria may lie in bed nets for adults and older children
... coverage in these high-risk groups. However, this strategy appears to overlook the benefits of protecting the rest of the population. Using recently-developed models of mosquito behaviour and mortality, researchers at the Ifakara Health Research and Development Centre in Tanzania, led by Dr Gerry Killeen...New approach to pulmonary hypertension shows promise
... "We believe this finding opens the door to a new strategy and the development of a new stream of drugs to treat this complex and lethal disease," said Dr. Evangelos Michelakis, director of the U of A pulmonary hypertension program and senior author of the study, which appears today in the Proceedings of the...New approaches to endometriosis treatment -- mouse experiments point the way
...ovarian hyper-stimulation syndrome, could be a new strategy for inhibiting endometrial lesions. We know that...geting dendritic cells may prove to be a promising strategy for treating conditions dependent on angiogenesis, such as endometriosis and cancer, says Dr. Fainar...Translating form into function
... enzymes function from its structure. If their new strategy works with other enzymes, it should become a poten...alled molecular docking, a computer-aided modeling strategy used to search for potential drugs. Docking works by allowing researchers to first determine the ato...Doing nature one better: Expanding the genetic code in living mammalian cells
...tute for Biological Studies have developed a novel strategy to expand the natural repertoire of 20 amino acids...amino acids in bacteria. His approach mimicked the strategy every cell relies on to incorporate conventional amino acids into proteins: During protein synthesis...Nanoparticles hitchhike on red blood cells: a potential new method for drug delivery
...e first to be piggybacking on red blood cells; the strategy has already been adopted by certain bacteria, such as hemobartonella, that adhere to RBCs and can remain in circulation for several weeks. The researchers say that it may be possible to keep the nanoparticles in circulation for a relatively long t......e first to be piggybacking on red blood cells; the strategy has already been adopted by certain bacteria, such as hemobartonella, that adhere to RBCs and can remain in circulation for several weeks. The researchers say that it may be possible to keep the nanoparticles in circulation for a relatively long t...Damon Runyon names new class of rising stars in cancer research
...e, Massachusetts, is devising a chemical synthesis strategy for the natural compound Cortistatin A, a novel anti-cancer drug that targets metastatic disease. David S. Matus, PhD, with his sponsor David R. Sherwood, PhD, at Duke University, Durham, North Carolina, is using a powerful genetic model to identify...Story ideas from Molecular & Cellular Proteomics
...Max L. Nibert, and colleagues takes advantage of a strategy used by a virus called mammalian orthoreovirus. When this virus infects a cell, it uses the cellular machinery to synthesize viral proteins that replicate the viral RNA and assemble new viruses. This process occurs in large structures called viral fa...ORNL-led team wins DOE bioenergy center
...ew methods of processing plants into biofuel. The strategy involves breaking down into simple sugars the lattice of cellulose, hemicellulose and lignin that makes plant cell walls resistant to the stress of weather, insects and disease. These sugars can then be processed into fuel. To date, no cost effective......ew methods of processing plants into biofuels. The strategy involves breaking down into simple sugars the lattice of cellulose, hemicellulose and lignin that makes plant cell walls resistant to the stress of weather, insects and disease. These sugars can then be processed into fuel. To date, no cost effective...