Journal of Nuclear Medicine Supplement summarizes current molecular radiotherapy
...lide therapy and to provide them with a summary of suggested patterns of practice for common radionuclide therapies now available. They also include a forecast of the near-term opportunities that are likely to determine practice in the next few years. Radionuclide therapy is an important and increasingly sign...Current human embryonic stem cell lines contaminated UCSD/Salk team finds
... In addition to using human serum, the researchers suggested the possibility of using what are called "feeder c...the Nature Medicine paper, noting that none of the suggested approaches guarantees the complete elimination of Neu5Gc from existing cultures. "Therefore, it wou...The Cochrane Library Newsletter, 2005, Issue 1
...10% and 20% will die. Animal research in the 1980s suggested that making an individual's blood more alkaline may aid their recovery. The Cochrane authors found no high quality clinical studies aimed at evaluating the effects of adding sodium bicarbonate to the blood of people who have...Loss of sight and enhanced hearing: A neural picture
... than those with sight. Neuroimaging studies have suggested that areas of the brain normally devoted to vision...s, better than those who could see. These findings suggested that areas of the brain normally dedicated to processing visual stimuli (the visual cortex, located ...Report assesses health implications of perchlorate ingestion
...approach to perchlorate risk assessment." It also suggested studies that have the potential to more precisely define "safe" perchlorate exposures. Future findings could result in the need to adjust the reference dose recommended in the report, the committee acknowledged. The study was sponsored by the U.S. E...Parents' attitudes to sperm donation still some concerns about being open
... could not be generalised to the whole population, suggested that lesbian couples and more privileged heterosex...resentative of DI parents as a whole, the findings suggested a marked proportion of parents recognised the importance of sharing DI information with their child....Steroid discoveries could add bulk to crop harvests
...the proteins were in a location and in a form that suggested they could regulate gene activity, they did not appear to possess any of the known structures found in transcription factors seen in either plant or animal cells, said Chory. But the researchers' experiments showed that BES1 does, indeed, bind to and...Racial groupings match genetic profiles, Stanford study finds
...ocial construct with no genetic basis while others suggested that clear genetic differences exist between people of different races. What makes the current study, published in the February issue of the American Journal of Human Genetics, more conclusive is its size. The study is by far the largest, consisting ...Discovery promises simpler therapy for sickle cell disease
...ong with oxygen and carbon dioxide. Those findings suggested that nitric oxide defects might play a role in the cardiovascular side effects of many disorders, including diabetes, heart attacks, septic shock and sickle cell disease. In the current study, the researchers found that hemoglobin in the red cells of...Blocking cell signaling can stymie viral infections, study shows
...is primed to become a factory for the virus. "This suggested that the process of viral replication could be hindered by short-circuiting the SPGF signaling pathway," Reinherz states. To test the idea, they injected SPGF-blocking antibodies into mice infected with a vaccinia virus (it carries a protein much lik...Increased risk of osteoporosis associated with gene that one in five people have
...f Bone and Mineral Diseases. "The link to estrogen suggested that the gene could also affect bone density. No one had ever investigated that possibility, so we set up a study to evaluate the relation between bone density and variations of the CYP1A1 gene." The researchers studied 156 women with an average age ...New neurons born in adult rat cortex
...responsible for mood dysregulation in depression," suggested Cameron. "But answers to such questions about regulation and possible functions of the new neurons must await results of future studies." Also participating the project were Kathryn Cleaver and Thamara Abouantoun of the NIMH Unit on Neuroplasticity....Gene used in brain development can cause childhood brain cancers
...how no activity for this gene. This latter finding suggested another approach, RNA interference, to blocking OTX2 activity. Discovered in the late 90's, RNA interference or RNAi refers to the introduction of double-stranded RNA (dsRNA) into a cell, where it induces the degradation of complementary messenger R...Pro-inflammatory protein contributes to Crohn's disease according to UCSD School of Medicine study
...g high levels of IL-1 secretion in the mutant mice suggested that in addition to activating the NF-kB, that mutant NOD2 also stimulated the processing of the IL-1 precursor into its mature form." The Karin team then gave an IL-1 inhibitor to mice and it abolished the experimental colitis (Crohn's Disease) in t...Drought reduces nitrogen-fixing in legumes
...ined on the exogenous application of abscisic acid suggested the existence of at least two different mechanisms for the regulation of biological nitrogen-fixing depending on how the stress evolves. In situations in which the stress is produced gradually, a route that is independent of abscisic acid is activate...Rats infected as newborns grew up vulnerable to memory problems during an immune challenge
...lecules, in response to germs. Prior research had suggested that higher IL-1BETA in the brain's hippocampus, a key memory area, disrupts the consolidation of memories following a learning experience. Thus it appears that there may be an optimal range for IL-1BETA, with either too much or too little inhibitin...Columbia study suggests brushing your teeth may reduce risk of stroke and heart attack
... to stroke or heart attack. Previous studies have suggested a relationship between periodontal disease and vascular disease, but they have relied on surrogate markers for periodontal disease, such as tooth loss or pocket depth. This is the first study to examine the microbiology of periodontal infection and ...Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits
...ding. Such networks enriched for several functions suggested to the researchers that cellular processes may work together in a coordinated fashion. In contrast, the team did not find in yeast a network they found in both worm and fly that is involved in the guidance of nerve cell axons to their synaptic targe...UCSD discovery may help extend life of natural pesticide
...us findings with the roundworm C. elegans strongly suggested that specific sugar structures are likely critical for Bt toxin susceptibility," said Joel Griffitts, the first author on the paper and a former graduate student with UCSD biology professor Raffi Aroian. "This latest paper demonstrates what these sug...Green tea extract shows promise as an anti-cancer agent, UCLA study finds
...t." Numerous epidemiologic and animal studies have suggested that green tea extract provides strong anti-cancer effects in several human cancers, including bladder cancer. It has been shown to induce death in cancer cells, as well as inhibiting the development of an independent blood supply that cancers develo...