Humble yeast sheds light on promising anti-cancer drug
...lethal against tumours because it chokes the blood supply they rely on to grow and spread." The amazing thing is that we've used the humble yeast, which is a less sophisticated cell than a human cell, to reveal the molecular secrets of the drug and how it works in humans. The GSAO story GSAO (glutathiona...Based on body size, bacteria and elephants have similar metabolism, ecologists find
...dings indicate there is a universal rate of energy supply per unit mass which can maintain life in organisms...e organs from the body surface. "This makes energy supply more and more difficult for larger organisms," he said. "For example, bacteria have to transport the...Stem cells' electric abilities might help their safe clinical use
...se human ESCs can potentially provide an unlimited supply of even highly specialized cells, such as brain and heart cells, for transplantation and cell-based therapies, they may provide an ultimate solution to limited donor availability. In an earlier study, Li's lab genetically engineered heart cells deriv...Study provides insight into cellular defenses against genetic mutation
...ediated mRNA decay (NMD), can nearly eliminate the supply of an mRNA template for an essential protein because the mRNA has acquired a nonsense codon. "Our study is important because we have determined for the first time that the mRNA-binding protein CBP80 tells the NMD system which mRNAs to review for nons...New book explains how evolution really works, rebuts intelligent design
...ssels grow until all the muscles have a sufficient supply of oxygen. Apparently very complex adaptations cantherefore be achieved with few, simple mutations. Today, it is understood for the first time that all animals use the same set of core processes to develop into adult forms. Applying this knowledge t...Pall tells FDA panel about blood filtering technology
...ory and health authorities on protecting the blood supply from prions that can cause vCJD. Studies Validating Filter Performance Dr. Coker presented research results on the ability of the filter to remove all types of prions from red cells including scrapie (a TSE affecting sheep); mouse infected with hu...California's oak woodlands face a new threat: Climate change
...e in the mountains, creating concern for our water supply and for the natural ecosystems that attract so many visitors."...UV measurement tool aids defense against microbes in tap water
...ntration of chemical byproducts found in the water supply and help to meet the new byproduct standards, in a...eak of Crypto transmitted through the public water supply infected an estimated 400,000 people in Milwaukee and led to more than 100 deaths, Linden said. In t...... general UK population." The potential gap between supply and demand has led senior author Dr Jane Stewart, consultant gynaecologist and specialist in reproductive medicine at the Newcastle Fertility Centre at LIFE, to call for a change of tactics in recruiting donors. "It is difficult and costly to recru...Unexpected function for a key regulator of blood glucose levels
...to provide a constant and readily available energy supply for the cells in our body. Right after a meal, when nutrient levels in the blood are high, the pancreas releases insulin, which tells muscle and liver cells to squirrel away glucose for later use. In addition, insulin stimulates the production of fat...Growers and homeowners can help detect citrus disease
...ning is not expected to have a major impact on the supply of citrus fruit this year, it is important that the spread of this disease be carefully monitored and reported, say plant pathologists from APS. To date, citrus greening has only been detected in Florida, but residents of all citrus growing areas in ...From one cell, many possible cures
...key issues constraining this research -- a limited supply of stem cells -- he could help advance the development of numerous medical therapies by years," Locke said. According to the Tulane Center for Gene Therapy's Web site, "stem cells are so named because they are like the stems on a tree that can produc...Jefferson biologist coaxing human embryonic stem cells to make dopamine with simpler, faster method
... brain cells that make dopamine, which is in short supply in the brains of individuals with Parkinson's. Such cells might be used for transplantation in these patients, but current methods involve extremely complex growth media and potentially contaminating animal products. Now, developmental biologist Lor...Studies show apo A-I Milano gene transfer and antibody therapy cut atherosclerotic plaque
...tant gene enabled animals to manufacture their own supply of the gene's protein product that protects agains...ing the virus so that the body can produce its own supply of apo A-I Milano. One single injection of the gene, carried by the virus, markedly reduces plaque b...Polymer gel can block toxic leakage problem in gene therapy
...mes larger than the width of the microvessels that supply the tumor with blood. The needle is also wider than the spaces between each of those vessels, he added. The first author of the British Journal of Cancer study was Yuan's graduate student Yong Wang. Other authors included Yuan, Yuan's research associ...First ever study to investigate impact of chronic wasting disease on humans
...' said Garruto. "Human health and keeping the food supply safe is of primary concern. But we also have to monitor how to keep this epidemic from spreading among deer and across species, from deer to cattle, both of which could have huge economic as well as health implications." Garruto notes that although a...JCI table of contents: November 23 2005
...ary vessels, preferentially migrate from the blood supply to the healthy lung, and are retained there in readiness in the event of infection. These results document a novel mechanism of effector T cell migration in the normal, non-inflamed lung a prime site of exposure to environmental antigens. The author...Transporters for the brain chemical serotonin provide
...udies, Dr. Levin found that frog embryos contain a supply of serotonin provided in the egg by the mother. This maternal serotonin functions during the first few cell divisions and then is degraded by an enzyme, monoamine oxidase, which has many important functions in human neurobiology. Chick embryos, on th...'Go Fishing' no game for inland waters worldwide
... remain high, overexploitation of the world's fish supply is rapidly threatening biodiversity and balance of... remain high, overexploitation of the world's fish supply is rapidly threatening biodiversity and balance of the ecosystem, according to new research in Decem......ntifications. Scores of micrographs are needed to supply the hundreds of thousands of particles in a typical large-molecule reconstruction, but a program user needs to set parameters like particle size and gray-scale range only once, on a single micrograph. Thereafter the program runs on its own, sorting t...