Tag: "synthesised" at biology news

Molecular miners find pain relief drugs from the sea

... the DNA sequence. The peptide was then chemically synthesised in large quantities suitable for biological testing. This same approach is now being used by Metabolic Pharmaceuticals to synthesise gram amounts of ACV1 needed for the planned human clinical trials for diabetic neuropathy. "With an increasing age d...

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

... available today. As the initial step, researchers synthesised nanoparticles for controlled drug release made from a biocompatible and biodegradable PLA polymer system and encapsulated a fluorescently labeled model drug within them, in order to visualise nanoparticle uptake into target cells. The nanoparticles i...

Injection may prevent infertility in men receiving cancer chemotherapy

... non-toxic immunomodulatory compound developed and synthesised by us. Tellurium is a transition element with similar properties to Selenium, which is also known to have many beneficial effects." Knowing that AS101 had been shown to have chemoprotective effects in both animal and human studies, he and his team d...

Scientists discover way to block growth of prostate cancer cells

...ators at Wayne State University, Detroit, MI, USA, synthesised a molecule called MDL 72,527 (MDL), which was previously known to be an inhibitor of acetyl polyamine oxidase (APAO). APAO catalyses the oxidation of acetyl polyamines produced by SSAT the process that results in the generation of ROS. MDL can, th...

Genetically engineered blood protein can be used to split water into oxygen and hydrogen

...an, in collaboration with Imperial College London, synthesised a large molecular complex from albumin, a protein molecule that is found at high levels in blood serum, and porphyrin, a molecule which is used to carry oxygen around the body and gives blood its deep red colour. Porphyrin molecules are normally foun...

New impetus through networking

...rganic framework (MOF) compounds, which were first synthesised in the 1990s, far exceed the capacity and the functionality of conventional porous materials. In the Priority Programme of the same name, chemists and physicists seek to create tailor-made MOFs, which can be used for energy storage, the separation of...

Manchester researcher wins Libyan award

...s, so a series of novel compounds was designed and synthesised to probe the active site constraints of the angiogenic enzyme, thymidine phosphorylase (TP). In work carried out in collaboration with Drs Sally Freeman and Mohammed Jaffar in the School of Pharmacy, Abdul showed that some novel compounds displayed g...

Frog molecule could provide drug treatment for brain tumors

... at hunting and destroying tumour cells, is easily synthesised in the laboratory and offers great hope as a therapeutic treatment of the future. Amphinase is a version of a ribonuclease enzyme that has been isolated from the oocytes (egg cells) of the Northern Leopard frog. Ribonucleases are a common type o...

Call for EU to launch major project to map out all our proteins

...me are confined to specific organs and/or are only synthesised at certain times or stages of an organisms life. However a recent workshop supported by the European Science Foundation (ESF) concluded that it is now feasible to map at least nearly the whole proteome (the sum total of all proteins) of an organism. ...

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(Date:4/17/2014)... hydrogen sulfide in order to properly multiply and form ... Center for Craniofacial Molecular Biology at the Herman Ostrow ... principal investigator on the project, said the presence of ... of calcium ions. The essential ions activate a chain ... creation of new bone tissue, and keeps the breakdown ...
(Date:4/17/2014)... in German . ... money demanded of him, he can expect his premises to ... fear of the consequences is enough to make restaurant owners ... which lay their eggs in other birds, nests. If the ... take their revenge by destroying the entire nest. Consequently, it ...
(Date:4/17/2014)... France have hit on a novel method to ... correct and most effective treatment possible., Kidney stones ... and developing world. If left untreated, apart from ... failure and other complications. In many patients treated ... a more effective pathological approach to diagnosis and ...
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