In a first, Einstein scientists discover the dynamics of transcription in living mammalian cells
...A polymerase II molecules assemble on DNA and then synthesize RNA by sequentially recruiting complementary RNA n...se starts up again, in a very short time you could synthesize a new batch of messenger RNA molecules that might suddenly be needed for making large amounts of a p...New grants bolster efforts to generate faster and cheaper tools for DNA sequencing
...lizes unmodified DNA base pairs and polymerases to synthesize DNA and a firefly enzyme to generate a chemiluminescent signal. Jingyue Ju, Ph.D., Columbia University, New York $2,217,000 (2 years) An Integrated System for DNA Sequencing by Synthesis This team will continue its development and optimization...Research shows NPD1 protects a key component of vision
...d primary human RPE cells and found that they also synthesize NPD1. The researchers showed that neurotrophins regulate NPD1 by stimulating its production and also controlling its release. They found that the neurotrophin PEDF not only sparks the production of NPD1, but it acts synergistically with DHA indicatin...Coming soon -- Protein synthesis without amino acids?
...x. The team was thus able to use this technique to synthesize polypeptides that have previously not been accessible by other means. As a next step, the Chinese researchers want to include not just one, but a variety of imines into the same chain....Tiny tweezers and yeast help St. Jude show how cancer drug works
...n fork can continue separating the two strands and synthesize exact copies of each chromosome. Topotecan exploits the binding of topoisomerase I to double-stranded DNA that occurs when the cell tries to separate these strands. Researchers already knew that topotecan poisons topoisomerase by binding to both th...New imaging method clarifies nutrient cycle
...stasizing tumor cell, and what does the tumor cell synthesize in order to make implantation possible" ...Mother-of-pearl -- Classic beauty and remarkable strength
...h and simplicity, she says. "We don't know how to synthesize materials that are better than the sum of their parts." Writing in the June 29 issue of Physical Review Letters, Gilbert and her colleagues in the UW-Madison department of physics and School of Veterinary Medicine, the Institute for the Physics of ...Pairing nanoparticles with proteins
...Throughout this work, the biggest challenge was to synthesize size-controllable nanoparticles coated with organic molecules designed to react with specific protein sites. Hu explains the steps: "First, we design the specific interactions between gold nanoparticles and the proteins by coating the gold nanopartic...Story ideas from Molecular & Cellular Proteomics
... infects a cell, it uses the cellular machinery to synthesize viral proteins that replicate the viral RNA and assemble new viruses. This process occurs in large structures called viral factories made by the virus inside the cell. Previous work had identified an orthoreoviral protein that can form very similar v...Scientists call for global push to advance research in synthetic biology
...ganisms that convert plant matter to fuels or that synthesize new drugs or target and destroy rogue cells in the body. The two-page statement calls for an international effort to advance synthetic biology that would not only propel research, but do so while developing protective measures against accidents and ...Discovery in orange cauliflower may lead to more nutritious crops
...liflower and many staple crops have the ability to synthesize beta-carotene, they are limited partially because they lack a "metabolic sink," or a place to store the compound. Developing staple crops with more vitamin A is important because vitamin A deficiency, common in developing countries, leads to compromi...Adult stem cells from human cord umbilical cord blood successfully engineered to make insulin
...ord blood-derived stem cells can be engineered" to synthesize insulin. "This discovery tells us that we have t...e insulin, which allows the body to utilize sugar, synthesize proteins and store neutral fats, or lipids. "But were a long way from that," Denner warned. Denne...ACS News Service Weekly PressPac -- May 16, 2007
... "Equipping bacteria that can degrade pollutants, synthesize and release therapeutics, or transport loads with an ability to localize to a specific chemical signal would open new frontiers in bioremediation, drug delivery, and synthetic biology," Emory Universitys Justin P. Gallivan and Shana Topp state in the...Study shows marine omega-3 fatty acids have positive effect on muscle mass
... amount of amino acids was used by their bodies to synthesize proteins, especially in muscles. So it appears that omega-3 fatty acids added to the steers diet replaced other fatty acids in muscle cells and improved their functioning. This finding could have significant implications in the field of animal farm...Arming the fight against resistant bacteria
...ers of molecules quickly and efficiently. They synthesize molecules directly on a flexible, paper-like sheet...r - so far, about two percent - but the ability to synthesize and screen such large numbers of candidates should still allow them to identify large numbers of new...An electroacoustic path to custom-made gene chips
...he authors said that they were working on a way to synthesize sequences longer than the 3-base n-mers the pilot machine produced. They have now done so. A new paper accepted for publication in IEEE/ASME Journal of Micro-Electro-Mechanical Systems, details how the system has been improved to allow synthesis ...UC researchers shatter world records with length of latest carbon nanotube arrays
...roperties. Intense research has been undertaken to synthesize long aligned CNTs because of their potential applications in nanomedicine, aerospace, electronics and many other areas. Especially important is that long CNT arrays can be spun into fibers that are in theory significantly stronger and lighter th......and interact with the transcriptional machinery to synthesize proteins. Marszalek and his colleagues have also examined synthetic DNA to figure out the extent to which different bases are affected by UV light. They conclude that the changes in the force profile of viral DNA exposed to UV light are due to the lo...UD scientist wins NSF career award for tissue engineering research
...ymer chemistry and physics. The lab was working to synthesize polymers for carrying cancer-fighting drugs in the human body. "One day, a farmer from a remote area in northeast China appeared in the lab, desperate to find a cure for his wife's cancer," Jia said. "We felt so bad for him," she noted. "That exper......lled cytidine triphosphate synthetase, which helps synthesize CTP, was inhibited by acivicin, an anticancer drug previously tested in humans and animals but now abandoned. The scientists tested the action of the drug on mice infected with the trypanosome parasite and showed that the infection was suppressed for...