ICCL and CI launch global mapping project to protect sensitive marine areas
...ry. The seven-member panel gathered, reviewed and synthesized a wide-range of available scientific data. The panel supplemented this research with an intensive series of interviews, stakeholder dialogues and discharge mapping exercises to identify and better understand the cruise industry's current waste manag...Study describes how cells return to normal after responding to stress
...stress, molecules known as heat shock proteins are synthesized by the cell to provide protection against protein damage. These heat shock proteins, Hsp's, are an important part of a large protein family known as molecular chaperones. Molecular chaperones help new or distorted proteins fold into the correct shape...New lipid molecule holds promise for gene therapy
...logy; and of physics at UCSB. The new molecule was synthesized in Safinya's laboratory by first author Kai K. Ewe... X-ray scattering experiments. Ewert designed and synthesized the new lipid by manipulating the size, shape and charge of a series of molecules. He explained that...Einstein researchers find potential new drugs for tuberculosis
...ein College of Medicine of Yeshiva University have synthesized chemicals that are up to 10 times more effective t...o improve upon isoniazid, the Einstein researchers synthesized more than a dozen chemical "decoys" for InhA to latch onto, to prevent the enzyme from catalyzing it...Researchers reverse juvenile diabetes in animal model; Clinical trial FDA approved
... known as CD40, CD80 and CD86, all of which can be synthesized in a laboratory. This treatment strategy was found to inhibit the interaction and destructive effect of T cells on the insulin-producing beta cells of the pancreas, a process that is known to be a critical part of how diabetes occurs. Subcutaneous in...Discovery at the Feinstein suggests new treatment approach for inflammatory conditions
...edient was first extracted from a plant and is now synthesized in the laboratory, which works primarily by blocking the enzyme that destroys acetylcholine. The drug allows the nerve cells in the brain to communicate their anti-inflammatory signals to the rest of the body. The FDA approved galantamine for mild to...Interfering RNA silences genes in 'slippery' immune cells
...expression cassette (SEC), an inexpensive, quickly synthesized product that carries genetic sequences to regulate the gene activity that yields an siRNA. After the researchers tested a variety of SECs to determine which is the most effective, they inserted the desired SEC into a vector, a biological agent that i...Gladstone scientists prove neurons produce Alzheimer's-linked apolipoprotein E
...l now, most researchers have believed that apoE is synthesized in the brain solely in such cells as astrocytes, microglia, and ependymal layer cells. Controversial for the last decade has been the question of whether or not neurons, which make thought and memory possible by transmitting electrical signals, can p...Nanotechnology shows early promise to treat cardiovascular disease
...t, creating a structure known as a micelle. Uhrich synthesized molecule chains with several different characteristics, such as attracting or repelling water or having a positive or negative charge. When the chains assembled into micelles, Mogue tested them for how well they blocked LDL uptake. "We're employing t...Unique dual target specificity of kinase inhibitor key for success against cancer
...s. UCSF colleagues Zachary Knight and Kevan Shokat synthesized and characterized a series of novel inhibitors that span the different PI3 kinase isoforms (described in the May issue of Cell). Qi-Wen Fan in the Weiss lab screened these agents in glioma cell lines. One compound, PI-103, uniquely and potently block...New compound reduces stroke damage
Bethesda, MD A group of German scientists has synthesized a new compound that dramatically decreases the dam... more predisposed to survive." The scientists also synthesized a molecule that specifically inhibits FKBP38 and administered it to rats that were experiencing stro...OHSU studying drug for bone-deforming disorder
...of Medicine, is examining the effectiveness of the synthesized parathyroid hormone, teriparatide, in increasing bone mass and improving bone structure in adults affected by OI. Teriparatide, derived from the human parathyroid gland, is manufactured and sold by Eli Lilly and Co. under the brand name FORTEO. FORTE...Harvard Medical signs agreement with Merck to develop potential therapy for macular degeneration
...mall molecule antagonists that they had previously synthesized and showed that they can also stop production of the retinotoxic lipofuscins. In mice that are genetically predisposed to forming excessive amounts of lipofuscin, administration of the inhibitors completely blocked formation of the A2E lipofuscins, t...Chemists forge a new form of iron
...ature, is an essential catalyst for life. "We have synthesized something totally new that nobody has imagined could exist, and something which adds greatly to our understanding of fundamental iron chemistry," says John F. Berry, an Alexander von Humboldt postdoctoral fellow at Germany's Max-Planck Institute for ...Is being overweight all in the brain?
... be treatable with drugs. Serotonin is a molecule synthesized by specific brain cells (neurons), and it serves as a messenger molecule between neurons, a so-called neurotransmitter, explained Erritzoe. It is released by one neuron and received by receptors sitting on another neuron. Serotonin is involved in the...African symposium to focus on how nature can help alleviate poverty
...um will include five plenary sessions that will be synthesized at the end to produce the Madagascar Declaration, a virtual blueprint for how African biodiversity can contribute to sustainable development and alleviate poverty and disease transmission.Plenary topics include: "Africa's Importance for Biodiversit...Epilepsy drug eases symptoms of inherited disorder that weakens muscles
...tment that can increase the amount of SMN2 protein synthesized by SMN2 genes. This rapid bench-to-bedside transition for valproate is a good example of the kind of progress that is encouraged both by NIH and the University's Biomed 21 initiative." In addition to its use as an epilepsy treatment, valproate, which...Genetics behind developmental brain disorders may play a wider role with congenital diseases
...w beta-actin to bind with ATP -- the chemical fuel synthesized by mitochondria that give a cell its energy. Beta-actin is a structural protein that helps form the cytoskeleton -- a cell's skeleton that gives it structure and strength. Unable to receive fuel, the mutated beta-actin proteins break down, ultimat...ACS Weekly PressPac -- July 12, 2006
...ommon type of seafood poisoning -- scientists have synthesized the toxin responsible for the disease. Estimates suggest that up to one million cases of ciguatoxin poisoning occur worldwide each year. In addition to serious acute symptoms, ciguatoxin poisons often cause long-lasting neurological problems. The a......act surgery. Mark W. Grinstaff and colleagues have synthesized and tested a new biocompatible adhesive gel that seals eye incisions quickly with the strength to keep the incisions sealed. Their report is scheduled for the current [July 19] issue of ACS Bioconjugate Chemistry . In about 11 million cataract op...