Medical steroid's baffling connection to osteoporosis becomes clearer
...teroid produced naturally by the adrenal gland and synthesized by a number of pharmaceutical companies for clinical use. The drug is also used to treat lupus, multiple sclerosis and chronic obstructive pulmonary disease, and it is prescribed to transplant patients to prevent rejection of transplanted organs. E...Amphibian declines, disease ecology, biodiversity are highlighted at conference
...in this session will review how long-term data are synthesized from a variety of ecosystem types for various ecological and social-science problems.An ongoing effort among several federal agencies to synthesize long-term data will be highlighted. Tues., Aug. 8, 8-10 p.m., Ballroom C, Ballroom Level. Landsc...A new tool against brain disease
...m. They determined its chemical structure and then synthesized more of the toxin, since they had only a small amount of the natural version. Next, the synthetic toxin was tested to see how well it acted as a "key" to fit into the "locks" represented both by binding proteins (from freshwater snails and a sea s...Viral oncoprotein inactivation of p53
...des a large tumor antigen (LTag) protein, which is synthesized early on and is necessary for productive viral infection. Once inside a host cell, LTag interacts with the p53 and Rb tumor suppressor proteins and renders them inactive. p53 and Rb inhibition drives cells into S phase, promoting both host and viral ...ACS News Service Weekly PressPac -- August 30, 2006
... at the University of Illinois at Urbana-Champaign synthesized QS-21A. In their latest report, scheduled for the Aug. 30 issue of the Journal of the American Chemical Society, the researchers provide key information that should enable scientists to make analogues, or molecular variants of QS-21A. That research m...Minnesota and Michigan reseachers discover new insights for antibiotic drug development
...or thousands of slightly different compounds to be synthesized and tested for antibiotic activity. The structure of macrolides is a large ring, itself constructed from a linear molecule, which is built in an assembly-line fashion from smaller molecules. An enzyme at the end of the chain triggers the ring form...An artificial cornea is in sight, thanks to biomimetic hydrogels
...postdoctoral fellow in Chemical Engineering, first synthesized the polymer that Myung ultimately developed. Qi Liao, a graduate student in Chemical Engineering, contributed to a general understanding of the hydrogels. Jennifer Cochran, assistant professor in the Bioengineering Department, is investigating how to...Ecological change, climate variation addressed at international conference, September 20-24
...nt communities are altered, a group of researchers synthesized data from nitrogen fertilization experiments at LTER sites across North America, including desert, tundra, salt marsh and prairie ecosystems. Ecologists Christopher Clark and Joe Fargione (Cedar Creek LTER), Steven Pennings (Georgia Coastal Ecosyst...Particle size matters to bacteria ability to immobilize heavy metals
...t microbial reduction of nano hematite, which Bose synthesized in the lab and characterized. "Nano particles of iron oxides are present everywhere and, due to their small size but large surface area, they provide bacteria a large amount of reactive sites," said Bose. "These particles are reduced by biological......ting with the sequences of two such peptides, they synthesized a series of different cyclic hexapeptides. Their trick was to replace one L-amino acid in each cyclopeptide with its corresponding D-amino acid. L-amino acids are the form that occurs in nature, D-amino acids are their mirror image. Whereas a "normal...Developing radiotracers for imaging studies in addiction
...otracer chemistry. In 1976, she and her colleagues synthesized 18F-fluorodeoxyglucose (FDG), the first radiotracer to measure brain glucose metabolism. As a stand-in for glucose, the body's main chemical fuel, FDG can help scientists monitor metabolic activity throughout the body and brain. Today, FDG is widely ...... carbon, all required amino acids and vitamins are synthesized by the subcuticular communities of microbial symbionts, providing their host with ample nutrition. On the other end of the digestive equation, such waste products as ammonium and urea, generated by the worm's metabolism, are taken up by these sym...ACS News Service Weekly PressPac -- September 27, 2006
...stals look much like the lead sulfide quantum dots synthesized recently using techniques from materials science, they state. "In contrast to modern nanotechnology, the dyeing process is characterized by basic chemistry methods and has been developed more than 2,000 years ago with low-cost natural products," the ...Uncovering DNA's 'sweet' secret
...han others," he said. Although homo-DNA was first synthesized in 1992, a detailed picture ofthe molecule's structure had been lacking. Egli's high resolutionstructure is now able to provide answers to some of the lingeringquestions about why DNA is made the way it is. While the homo-DNA structure shows a numbe...Nanoparticle assembly enters the fast lane
... steps," Maye said. The research team probed the synthesized and assembled nanosystems with multiple imaging techniques, using beams of light and electrons as well as high-intensity x-rays at Brookhaven's National Synchrotron Light Source. The scientists look to further improve the controllability of the syste......ains molecules that cause cell fusion) or ligands, synthesized by the collaborators from Collge de France, were incorporated into the lipid membranes. Two unilamellar vesicles were aspirated by two glass micropipettes. Close proximity of the vesicle membranes was achieved by displacing these micropipettes. Membr...Researchers find 'zip code' spurs cargo transport in neurons
...nt beads for virus and coated them with chemically synthesized peptides based on the sequence of human and squid APP. The squid sequence was obtained through a new squid genome project initiated at MBL by study co-author Joseph DeGiorgis. Bearer and her team injected the beads into squid axon then watched throug...UC given $1 million to develop skin cancer prevention treatment
...ructor, to determine the ability of alpha-MSH, and synthesized versions of it, to reduce DNA damage in melanocyte...PhD, of UC's department of surgery, will study the synthesized peptides on artificial skin to determine whether, if applied as a topical cream, they can be absorbe...Bacteria in small sea life yield new way to make potential cancer drugs
...By mimicking this natural process, the researchers synthesized a completely new compound. This paves the way to t...pounds." Now that they've shown compounds can be synthesized from DNA, the researchers want to figure out how to produce greater quantities of compounds for test...UCLA engineers develop revolutionary nanotech water desalination membrane
...e polymer film, Hoek's membrane contains specially synthesized nanoparticles dispersed throughout the polymer -- known as a nanocomposite material. "The nanoparticles are designed to attract water and are highly porous, soaking up water like a sponge, while repelling dissolved salts and other impurities," Hoe...