Natural polyester makes new sutures stronger, safer
...dustrial production of desirable natural compounds synthesized by those bacteria. The researchers focused their "biopolymer engineering" efforts on a group of genes that code for enzymes in a pathway that produces polyesters. Those polyesters can be broken down into metabolites naturally produced by humans, so...Nanoparticles for delivery of prostate cancer treatment
...s procedure is less effective than having the Icon synthesized in vivo" said Garen. "We prefer to deliver the Icon gene to tumor cells, so that they cause their own destruction." The Yale scientists previously used a virus to deliver the Icon gene, a system that was effective and safe in animal models and is b...Light-activated therapy targets DNA components
... March 25-29. We use visible light to signal the synthesized bioactive molecules to cleave DNA, said Karen Brewer, professor of chemistry at Virginia Tech. Incorporating a DNA target allows more selectivity. Coupling of the DNA targeting unit allows us to produce colored DNA-Complex assemblies that are easily ...OHSU lab finds meth receptor that could lead to therapy
...California, San Francisco. Scanlans laboratory has synthesized more than 150 new compounds that are being analyzed for their ability to selectively interfere with TAAR1 and block its activity. "So we're already on a roll," Grandy said. The goal is to "take them to the point where they can be tested in humans....The Institute of Ecosystem Studies to host an international conference on ecology and urban design
...ban design be improved? The conference will be synthesized by ecologist Steward Pickett of the Institute of Ecosystem Studies and designer Charles Waldheim of the University of Toronto. Conference proceedings will form the basis of both a book and a website. These end products will be used to connect recomme...Hamilton College researchers discover molecules with potential to treat breast cancer
...tists from the Albany Medical College subsequently synthesized the predicted molecules and showed that they were ...ucture of the larger peptides. These peptides were synthesized and shown to inhibit estrogen-dependent cell growth in a mouse uterine growth assay, a test showing ...Researchers at Illinois explore queen bee longevity
... the fruit fly influenced longevity. Because Vg is synthesized in fat body cells in honey bees, the team decided to look at Vg expression in the head and thorax as well as the abdomen. This led to an important discovery. Expression of Vg was high in the abdomen in the young queen and declined over time, but in...UC engineering researchers uncover factors that control ion motion in solid electrolytes
...ve like fish through water," says Boolchand. We synthesized materials of the composition (AgI)x(AgPO3)1-x in a glassy or disordered state, and then examined their thermal, optical and electrical properties as a function of chemical composition. (Here "x" represents the amount of AgI electrolyte, and 1-x the...Plants tag insect herbivores with an alarm
...icitors need to realize those elicitors may not be synthesized byor even exist withinthe insect pest species," Schmelz said. "Instead, the attacker's proteases may interact with the host proteins, generating an elicitor." Building on this work, Schmelz is now recruiting a post-doctoral scientist to help the team...Iowa State scientists demonstrate first use of nanotechnology to enter plant cells
... clever modification on the particle surface. They synthesized even smaller gold particles to cap the nanoparticles. These "golden gates" not only prevented chemical leakage, but also added weight to the nanoparticles, enabling their delivery into the plant cell with the standard gene gun. The biologists succ...Researchers shed light on mechanism of action used by anti-cancer drug
...Mcl-1 translation, a process in which proteins are synthesized from their constituent amino acids. However, the mechanism by which protein translation was inhibited by sorafenib remained largely unknown. In the present work, Grant and his team found that in human leukemia cells, sorafenib induces a process kno...Northern forests less effective than tropical forests in reducing global warming
...raft across the globe for decades but never before synthesized to study the global carbon cycle. The team found that some 40 percent of the carbon dioxide assumed to be absorbed by northern forests is instead being taken up in the tropics. "Our study will provide researchers with a much better understanding of...Bright future for nano-sized light source
...nique in which nanowires of potassium niobate were synthesized in a special hot water solution and separated using ultrasound. The wires were highly uniform in size, several microns long, but only about 50 nanometers in diameter. A beam from an infrared laser was used to create an optical trap that allowed indiv...New tool for marine conservation
...ation planning. The new, hierarchical system is synthesized from past global and regional classifications and extensive expert consultation. It includes 232 distinct ecoregions nested within 62 provinces that are in turn grouped into 12 realms. Each ecoregion has a relatively homogenous and distinct species c...JCI Table of Contents -- July 2, 2007
... AHSP is important not only for dealing with newly synthesized excess alpha-globin, but also in the assembly and stabilization of normal amounts of hemoglobin, even when alpha-globin is deficient, indicating unique and previously unidentified roles for this molecule. In an accompanying commentary, Arthur Bank ...Negative effects of plastic's additive blocked by nutrient supplements
...ed, she added. BPA is a synthetic estrogen first synthesized in the 1890s and is used in the manufacturing process from such everyday products as plastic water bottles, food containers and baby bottles. While laboratory studies have uncovered possible health concerns in animals, there has been considerable deb...In a first, Einstein scientists discover the dynamics of transcription in living mammalian cells
...gation proceeded much faster about 70 nucleotides synthesized per second than has previously been reported. These two phenomena pausing and rapid RNA synthesis during elongation may be crucial for regulating gene expression. With this sort of mechanism, you could have everything at the ready in case you su...