New grants bolster efforts to generate faster and cheaper tools for DNA sequencing
...ectively could enable health care professionals to tailor diagnosis, treatment and prevention to each persons unique genetic profile. The new grants will fund eight investigators to develop revolutionary technologies that would make it possible to sequence a genome for $1,000, as well as three investigat...Molecular detectors may refine cancer treatment
...ive tool to more precisely make a diagnosis and to tailor treatments. UF researchers built designer probes using cancer cells as a template, capitalizing on the ability of aptamers to fold into well-defined, three-dimensional structures that bind to targets. The process relies on the fact that different t...Crystal structure enables tailoring of pharmaceuticals against asthma
...ntified. With this knowledge it is now possible to tailor new molecules that can block the LTC4 synthase. The new results are also very important as they can lead the way for the development of new and more effective therapeutics against other diseases. Some 40 % of the proteins of interest for pharmace......els at 2,000, 4,100 and 8,000 feet. Our task is to tailor the Homestake site for science access and reduce its foot-print to only the areas of greatest scientific interest. Science at Homestake-SUSEL Prominent among the experiments that require the ultra-low backgrounds realized at great depths are s...Genetic roots of bipolar disorder revealed by first genome-wide study of illness
... and clinicians need more options so that they can tailor treatments to each patient. People inherit different gene variations, which may influence whether or not they respond to a given medication. Identifying and targeting these variations could help scientists develop additional medication options that...Work with nanoparticles may lead to 'on-the-spot' virus detector
...search, the UB engineers used directed assembly to tailor dielectrophoretic forces, which act through a nonu... may work best. By using directed assembly, we can tailor the forces acting on the nanoparticles. The ability to use several forces acting in tandem becomes i...Nanotechnology provides 'green' path to environmentally sustainable economy
...es. "With greater ability to manipulate matter and tailor properties, it should be possible to make products and processes with reduced toxicity, increased durability and improved energy efficiency," according to the report. For example, James Hutchison, a University of Oregon chemist, uses DNA molecules ...Discovery of new family of pseudo-metallic chemicals
...e pseudo-metals, which gives us the opportunity to tailor them to our needs, whether that is biomedical, chemical or electronic applications, some of which may utilize nanoscience." ...Nanotechnology offers hope for treating spinal cord injuries, diabetes and Parkinson's disease
... that someday should enable medical researchers to tailor and deliver individualized patient treatments in previously unimaginable ways. Stupp and his coworkers designed molecules with the capacity to self-assemble into nanofibers once injected into the body with a syringe. When the nanofibers form they can...Genes and biomarkers that allow doctors to choose the right therapy for the right patient
... "We need better ways to identify how we can best tailor existing therapies to individuals and how to target experimental agents." Gray and his colleagues have developed a system to evaluate drug response comprised of a panel of 50 breast cancer cell lines. Each of these cell lines represents a single va...Gene mutations linked to hereditary lung disease
... immune suppression therapies, we could eventually tailor drugs to a different target."...Gene test shown to measure heart function after transplant
...plant function may provide a valuable tool to help tailor therapies to meet the specific needs of each heart transplant patient," said Dr. Deng. Until recently, following a heart transplant, patients had to go through invasive heart-muscle biopsies to check for organ rejection. The GEP test is a non-inva......gen presenting, which enables the immune system to tailor antibodies to a specific enemy, and the activation of certain immune cells that engulf and destroy pathogens. But new findings published recently in the Proceedings of the National Academy of Sciences (PNAS) show that the third type of interferon o...Ultrathin films deliver DNA as possible gene therapy tool
...A bigger arsenal of tools may allow researchers to tailor films for specific applications. In addition to delivering DNA from stents, Lynn envisions using these nanoscale films to deliver DNA from other implantable devices. The films may also improve methods for engineering lab-grown tissues, in which pre...MIT particles pave way for new bedside diagnostics
...ch biological test, said Doyle. "It's very easy to tailor what you give a customer. You could have 100 types of particles and mix them together," he said. The researchers' particle fabrication method gives them exquisite control over the particles' shape and chemical characteristics. As two streams of...Research identifies causes contributing to poor development of over 200 million children worldwide
...the findings from the Lancet series can be used to tailor existing intervention programs or create new ones that better address the causes of developmental deficiencies in children. "We don't want this to be just another report that sits on a shelf," Wachs said. "To be more than that, we have to make spec...Three young scientists at Yale honored with Sloan Foundation Fellowships
...naturally. "Consciously and unconsciously, parents tailor their actions and the environment to their child. They draw attention to important aspects of a task and generally adapt the task to the child's capabilities," said Scassellati. "By building our machines to elicit this same type of behavior from huma...Weizmann Institute scientists discover genes that can slow cell division and may fight cancer
...fects responsible for each cancer and help doctors tailor a treatment fitted to each patient. Such a genetic profile can also help predict the individual progression of the disease. In the future, the identification of the exact factors causing uncontrolled cell division in different cancers might lead to t...Gene profiling predicts resistance to breast cancer drug Herceptin
...the tumor tells us before any treatment starts and tailor therapy accordingly," she said. To determine Herceptin sensitivity, investigators took a small tumor biopsy from 48 patients with newly diagnosed and operable stage II/III breast cancer. They examined the biopsy tissue using both single and multi-g......believes using information about genetic traits to tailor medications to individuals could make them significantly more effective. "The type of variant you have at this particular receptor the alpha-5 nicotinic receptor may actually predict whether or not you will do well on nicotine replacement therapy,"...