Overfishing great sharks wiped out North Carolina bay scallop fishery
... for shark fins and meat," Baum said. Sharks are targeted in numerous fisheries, and they also are snagged as bycatch in fisheries targeting tunas and swordfish in both U.S. and high-seas fisheries. As many as 73 million sharks are killed worldwide each year for the finning trade, and the number is escalati...Setting sights on the drugs of the future
...new areas for research into treatments that can be targeted at cancer, arthritis, cardio-pulmonary disease and...ner to help develop pioneering treatments based on targeted therapeutics regarded as one of the significant future areas in 21st century medicine and in which ...Clues to gene expression in cystic fibrosis will guide research
...ld help provide cystic fibrosis (CF) patients with targeted treatment in future, pilot study authors suggest. Results from a French clinical trial published today in BMC Medicine show how a small percentage of CF sufferers with a rare genetic stop mutation responded positively to gentamicin treatment. Aleks...Chromosomal microarray analysis proves accurate
...ul in identifying chromosomal abnormalities. The targeted microarray analysis used here is essentially a gene chip method of assessing the makeup of chromosomes in a particular part of the human genome (genetic blueprint). In areas of the genome, there are portions of the genetic material that show imbala...International risk research strategy and funding needed for nanotech safety
...minimum of $100 million over the next two years in targeted risk research in order to lay a strong, science-based foundation for safe nanotechnology. According to Maynards analysis, despite investing more than $1 billion annually on nanotechnology research, U.S. government spending on highly relevant nanotech...Nanoparticles for delivery of prostate cancer treatment
...Foundation to expand research on the delivery of a targeted therapy for prostate cancer using nanoparticles. ...g Garen will test the efficacy and safety of using targeted liposomal nanoparticle vectors lipid-covered, gene delivery packets to deliver the therapy in anim...Notorious cancer gene may work by destroying messenger
...RNAs which will also tell them what proteins are targeted and destroyed by PMR1. That will help tell us whether Src works through PMR1 to contribute to cancer, Schoenberg says. Funding from the National Institute for General Medical Sciences supported this research....UBC discovery may lead to 'smart' therapies for breast, ovarian cancer
New non-toxic and targeted therapies for metastatic breast and ovarian cancers may now be possible, thanks to a discovery by a team of researchers at the University of British Columbia. In a collaboration between UBC stem cell and cancer scientists, it was found that a prote...Study reveals how some molecules inhibit growth of lung cancer cells
...lar Pharmacology at Harvard Medical School. "These targeted therapies likely would be less toxic as they, in theory, would not affect the normal functioning EGFR proteins."...Shilatifard and colleagues identify a potential target for treatment of mixed lineage leukemia
...findings give us a promising option for developing targeted treatments to combat these types of leukemia."...Bacterial walls come tumbling down
... assembly of the sugar coating. The second step is targeted by penicillin and has been well studied. Although scientists have spent many years identifying bacterial components whose structural features might have weaknesses that can be exploited by antibiotics, progress in turning up bona fide drug targets ...NDDO and ESMO joined by US National Cancer Institute in conferences on targeted cancer therapies
...hase clinical trials and translational research of targeted agents for cancer therapy. John E. Niederhuber, M.D., NCI Director and NCI staff will join the Organizing Committee and the Scientific Advisory Board of the TAT series as of TAT 2008. Professor Hkan Mellstedt, ESMOs President, said that ESMO fully...Drivers and passengers on the road to cancer
...e cancer is crucial in order to develop accurately targeted treatments." The new research shows cancers in a different light and highlights many different insights into how cancers develop. The challenge will be distinguishing the drivers from the passengers. In some cases this is straightforward. For man...Breast cancer treatment heats up
...probes could be produced and used with molecularly targeted therapeutic heat to kill malignant breast cancer cellswithout damaging nearby healthy tissue. While many researchers have studied using heat in treating cancer, "the inability to deposit effective doses of heat in a tumor without applying similar ...Researchers wake up viruses inside tumors to image and then destroy cancers
...reened 2,700 agents until they hit upon Velcade, a targeted chemotherapy drug already approved for use in multiple myeloma. "We were both surprised and lucky," he says. "Velcade is a proteasome inhibitor, but it also induces the lytic cycle thereby activating the TK in the Epstein-Barr virus. Once the TK is ...UCLA study uncovers clues for why Graves' disease attacks the eyes
...tients contain an abnormal surplus of the receptor targeted by this antibody. An antibody must latch to a specific receptor like a key into a lock -- in order to elicit a cellular response. The receptors mobbed the patients immune systems, even on T-cells that normally would not produce them. "We didnt...JCI table of contents -- March 1, 2007
...ewborn children were proteins that are known to be targeted in autoimmune diseases, leading the authors to suggest that these natural IgM antibodies might provide the basis for the emergence of autoimmune diseases later in life. By contrast, in an accompanying commentary, Eric Meffre and Jane E. Salmon from W...Making daughters different -- how immune cells take divergent paths when fighting infections
... information that may one day be applied to a more targeted approach to developing vaccines." Immune cells first need to recognize infecting microbes, then divide and differentiate into the type of immune cells that fight off infection. But how, after replicating, do the new daughter cells know to become fi...Nanotech promises big things for poor -- but will promises be kept?
... invest in the appropriate nanotechnology research targeted at the developing world. Government foreign assistance agencies do not often focus, or focus adequately, on science and technology. With scant public awareness of nanotechnology in any country, there are few efforts by nongovernmental organizations (...Creating new life forms that may help eradicate cancer affecting women
... "teach" the immune system to mount a specialized, targeted response that is lethal to cancer. When Listeria is introduced in the body, it has a powerful, direct stimulatory effect on the activities of tumor-killing T cells. "Essentially the modified Listeria vaccines harness the power of the immune syste...