Mosaic mouse technique offers a powerful new tool to study diseases and genetics
A powerful laboratory technique used by fruit fly geneticists for more than a deca...early 1990s, scientists developed a more efficient technique that allows researchers to control when and where mutant cells are generated in the fly's body.Howev...Microbes yield secrets of survival
... "fool's gold." The researchers used an analytical technique called mass spectrometry to identify the proteins present in the biofilm, then correlated them with genes from each of the major organisms identified in the earlier genomic study. They found that many community functions, such as nitrogen fixation, a...New thermometer reveals wet conditions on earliest Earth
... research provides important information and a new technique for making additional discoveries about the first eon of Earth's history, the Hadean eon, a time period for which still little is known. The research findings are reported in the May 6 issue of the journal Science in a paper titled "Zircon Thermomete...Researchers map 'circuitry' of yeast genes using technique that could be applied to humans
Researchers at UCSD have invented a technique that organizes the genetic information contained i...f Bioengineering. Ideker and Kelley designed their technique to take advantage of an expanding library of interactions of yeast genes. Discovering such interacti......ing gene expression. Future gene therapy may use a technique in which non-invasive magnetic resonance imaging (...the need for an additional contrast material. This technique has far-reaching implications for monitoring the progress of gene therapy, such as that used to reac...Gold nanoparticles may simplify cancer detection
...re 35 nanometers in size. Researchers tested their technique using cell cultures of two different types of oral...ncer cells and noncancerous cells. What makes this technique so promising, said El-Sayed, is that it doesn't require expensive high-powered microscopes or lasers...Stem cell treatment improves mobility after spinal cord injury
...n tissue. For the study, the UCI team used a novel technique they created to entice human embryonic stem cells to differentiate into early-stage oligodendrocyte cells. Oligodendrocytes are the building blocks of myelin, the biological insulation for nerve fibers that is critical for maintenance of electrical c...Creation of gene targeting earns Smithies March of Dimes honor
...being honored for developing gene targeting. Their technique gives scientists around the world the ability to alter particular genes in cultured cells and transfer those targeted genes to laboratory mice. Gene targeting thus allows them to design and produce "knockout" lab mice to study how the disabled gene w...Molecular spies illuminate drug resistance proteins
...b said. Using a sophisticated molecular espionage technique called spin labeling, Mchaourab and colleagues attempted to make that movie. First, they isolated MsbA protein from E. coli and inserted the pure protein into liposomes, synthetic membranes that mimic the protein's natural home in the cell membrane....Atmosphere may cleanse itself better than previously thought
...difficult to study. "Thanks to an innovative laser technique that at last allows us to observe these chemicals ...Sinha and Matthews performed at UCSD, used a laser technique that allowed the team to look at the OH radical-producing molecules in a new way. More precisely, it......PR40 activity. In the first, the scientists used a technique known as gene knock-out to prevent production of the GPR40 receptor. The second type had overactive GPR40 genes creating a surfeit of fat-signaling receptors that tricked the beta cells into sensing high fatty acid levels, even on a normal diet. Thro...Engineers improve plastic's potential for use in implants by linking it to biological material
...r tissue-engineering purposes. "This is a powerful technique that can be used for biomaterials modification," Schmidt said, "and it hasn't really been explored very much until now."...New collision looks imminent for B-15A iceberg
...Envisat ASAR GMM mosaics and SAR interferometry a technique used to combine radar images to measure tiny centimetre-scale shifts between acquisitions - should answer the question of whether the kind of ice-shelf calving that gave rise to B-15 and its descendants are a consequence of ice sheet dynamics or othe...Like the famous doughboy, nanotubes give when you poke 'em
...nt radii. What we found was that as we tested this technique with wider and wider nanotubes, the bigger tubes were much less stiff than the smaller tubes," said Riedo. Riedo and colleagues began with a single-walled nanotube with a radius of only 0.2 nanometers and slowly inched, or rather nanometered, their w...Same fold in viral shells point to common ancestry
...which infects E. coli bacteria. Researchers used a technique called cryoelectron microscopy to determine the th...and then analyzed it with X-ray crystallography, a technique in which X-rays pass through a crystal, creating a "diffraction pattern" that can be interpreted wit...Gene keeps neural cells on correct developmental path
...e to study. Using knockout technology -- a popular technique for determining gene function -- does not work for REST because mice lacking the gene die before they are born. Embryonic stem cells provided a way for Mandel to get around this problem. Unexpectedly, they also revealed fundamental ways in which stem...Lack of coherent cloning policies reflects polarized debate, limited understanding, study says
...CAPE Somatic cell nuclear transfer (SCNT) is the technique currently in use to create embryos that are genetically identical to another animal or person, the report explains. Research cloning has been used in the laboratory to derive human stem cells from cloned embryos; their nuclear genome is identical to...One gene links newborn neurons with those that die in diseases such as Alzheimer's
...hin slices of brain tissue, the researchers used a technique called laser capture microdissection to collect ce... particular gene producing it. The microdissection technique uses a low-power laser to melt a small circle of film into the tissue. When the film is lifted, the ...BC scientists coax gold particles to emit light strong enough to view single nanoparticles
...cles into strong emission of visible light using a technique called multiphoton absorption induced luminescence...studied. "One of the most exciting aspects of this technique is that it paves the way for being able to observe behavior in living tissues at the single molecule...... genetically matched to specific people. But their technique could already be obsolete. Another team headed by ...time. But there were doubts about the results. The technique requires an adult cell and an egg, and because in Hwang's experiment both came from the same person,...