UF researchers awaken vision cells in blind mice
...d mice were evaluated using an exam akin to an eye test at the doctors office. In experiments overseen b... "Animals are much more difficult. What makes this test so fantastic is that it involves an animals natural response, and the results tell us that the anima...New techniques redefine assessment of liver disease
...previously demonstrated that a less invasive blood test to determine caspase three-generated cytokeratin 1...ients with NAFLD, supporting the potential of this test in clinical practice as a noninvasive NASH biomarker. In addition to finding that CK-18 could work ...... change during their lifetime. The challenge is to test these ideas." The authors warned that the study's primary implication-that body size need not be considered when comparing brain size-shouldn't be taken too literally. Deaner noted, "We believe that most of the relationship between brain size and b...Antibody-based therapies effective at controlling malaria
... The model described in this study provides both a test for therapeutic antibody efficacy prior to clinical trials in humans and an important tool in malaria vaccine development. ...No magic tomato? Study breaks link between lycopene and prostate cancer prevention
...cer. The men were initially screened through a PSA test and digital rectal exam, and were then followed through routine exams and screenings until first occurrence of prostate cancer, death or the end of the trial in 2001. At the beginning of the trial, the men gave a blood sample and completed a question...Executable biology -- Computer science sheds light on animal development
...ses taking place. Researchers can use the model to test hypotheses that would fill in the missing pieces in silico before performing actual lab experiments. By running their model with a wide variety of gene mutation scenarios and comparing results with available laboratory data, they found that the fat...Natural immune-control system may aid treatment of autoimmune disease and tissue rejection
...ls, the T cells are protected from destruction. To test this, they produced activated T cells that either lacked the Qa-1Qdm receptor or had a faulty version of it, preventing them from binding to the NKG2A receptor. The result was that the T cells became vulnerable to attack from a set of NK cells. Usin...The Institute of Ecosystem Studies recognized by the Wildlife Society
...nts. In addition to passing a firearms proficiency test and attending a pre-hunt orientation meeting, participants must be sensitive to the fact that the hunt takes place on an active research campus with numerous field sites." To date, the IES Deer Management Program has revealed useful information ab...Herpes infection may be symbiotic, help beat back some bacteria
...of bacteria. This led Virgin and his colleagues to test herpes-infected mice with exposure to the bacteria Yersinia pestis, which causes plague, and Listeria monocytogenes, which is a minor cause of food poisoning and can infect the central nervous system. Many aspects of Listeria infection in mice are al...Pediatric cancer stem cell identified: understanding the origin of ERMS
...ues have developed an animal model to identify and test therapeutic targets of human ERMS. The scientists artificially activated the RAS pathways to induce ERMS in a strain of genetically engineered zebrafish. Some transgenic zebrafish developed visible tumors by 10 days of age. Through their model, Dr...Mechanism of microRNAs deciphered
...hat uncovered the mode of action of microRNAs in a test tube. The study, which is published in the current...stigate the locking process itself, we developed a test tube system that recreates close to real life conditions of fruitfly embryos. Adding messenger RNAs ...Peanut allergies overstated, study finds
...at them everyday, then have a positive peanut skin test and are told not to eat them," said Dr Wainstein. ...anuts and are found to have a positive peanut skin test are probably NOT allergic to peanut and will need a peanut challenge to determine if they are allerg...Tips from the Journals of the American Society for Microbiology
... Researchers from Denmark have developed a 12-hour test for detecting Salmonella in meat. They report their findings in the May 2007 issue the journal Applied and Environmental Microbiology. Salmonella is one of the main causes of food-borne illnesses worldwide. Detection methods have proved costly an...'Nondanger' signal lowers immune reactions
...many organs. A next step, said Dr. Gallucci, is to test the antibody in mice that have a disease similar to lupus in humans. The study team also expects to test the antibody in animal models of rheumatoid arthritis. In addition, the researchers may investigate ...Gene thought to assist chemo may help cancer thrive
...ival." McDonald and colleagues are continuing to test their theory by conducting studies in cell cultures and mice. If it bears out, then disabling the gene in tumors, through medications or new genetic techniques during chemotherapy may help patients survive....DOE JGI sets 'gold standard' for metagenomic data analysis
...s constructed by the authors provide a much-needed test bed for evaluation and comparisons of these tools. Their findings will no doubt have a very significant impact on the field of metagenomics in general. It will help groups like mine to choose efficient strategies for the development of automated met...Asexual worm quickly adapts to soil contamination
...cies. At present these asexual species are used as test organisms in ecotoxicological risk evaluations. The question now arises as to whether they are suitable for this purpose. The results of this study are important for the development of protection strategies for natural populations. This can be rea...Subtle signs can help predict Huntington's disease early
...task. Those who performed worse on the psychomotor test than on the verbal fluency test were twice as likely to be diagnosed with Huntington's disease a year and a half later than those wh...'Might have been' key in evaluating behavior
...ague and his colleagues used an investment game to test the effects of these "what if" thoughts on decisions in 54 subjects. Using functional magnetic resonance imaging (fMRI) to measure blood flow changes in specific areas of the brain, they precisely measured responses to economic instincts. These bl......in theory at least, possible to list and therefore test all of the states it can be found in. "But when ...ed that will allow us to predict the behaviour and test the design. "Techniques developed in mathematics to predict the time course of continuous systems ...