2 million dwarfism study launched
... to help this generation but we are confident such therapies will be available to the next generation. Certainly, the genetic models we now have will prove extremely useful in helping us to achieve this goal....Scientists honored with 'Excellence in Clinical Research Award'
... applying combination therapies. If combined with therapies that block the autoimmune attack, a treatment that...s into clinical development, including combination therapies for beta cell regeneration. Previously, Dr. Cruz co-founded Angiotech Pharmaceuticals Inc, in Canada...Researchers discover inherited mutation for leukemia
...sis of CLL, and direct us to target this gene with therapies that might re-activate it." The findings also provide evidence that some genes might contribute to cancer even when they are not silenced entirely. "This inherited change is remarkably subtle," says co-principal investigator Albert de la Chapel...Long-term ulcerative colitis study shows Remicade responders maintained improvement
... social and professional life. The availability of therapies that quickly reduce symptoms and maintain response and remission long term is a significant benefit to patients." Separate data also presented at DDW today show the significant impact of UC on patients' productivity, employment and social activitie...A close-up on pancreatic disease: How do we improve the odds?
...ve Patient Survival (Abstract #964) As targeted therapies become more reliable, researchers are searching fo...therapeutic targets, with the concept of tailoring therapies to patients who will respond better to certain regimens. Epidermal growth factor receptor (or EGFR)...Exercise reverses aging in human skeletal muscle
...ts for chemical screenings that could lead to drug therapies that would modulate the aging process. "The vast majority of aging studies are done in worms, fruit flies and mice; this study was done in humans," said Melov. "It's particularly rewarding to be able to scientifically validate something practical ...Immune antibodies penetrate neurons to clear Alzheimer's-linked amyloid
...tten much closer to understanding how immune-based therapies can treat Alzheimer's disease -- by studying how antibodies go inside brain cells to reduce levels of Alzheimer's-linked amyloid peptides that form plaques between neurons. "This internalization and activity of the antibody within the cell was a bi...FSU engineering professor growing bone in a lab
...is its potential for developing new treatments and therapies for military personnel who have suffered bone loss due to diseases or traumatic injuries," Ma said. "However, many other types of patients who suffer from bone diseases could benefit from this research as well." Ma pointed to recent students showin...Weill Cornell pharmacologist receives prestigious NIH MERIT Award
...eral blood flow, and uncover potential targets for therapies aimed at patients with diabetes." In 2006, Dr. Gross reported the first-ever method of combing through the body's tens of thousands of proteins to inventory sites of S-nitrosylation (S-NO), a protein associated with NO. The state-of-the-art mass sp...In a first, scientists develop tiny implantable biocomputers
...uld eventually revolutionize medicine by directing therapies only to diseased cells or tissues. The results will be published this week in the journal Nature Biotechnology. "Each human cell already has all of the tools required to build these biocomputers on its own," says Harvard's Yaakov (Kobi) Benenson...Digestive Disease Week 2007 spotlights breakthrough research in digestive health
...ealth, including: Better diagnostics, stronger therapies and more effective procedures for colorectal cance..., ethnicity and risk of GI diseases Up-and-coming therapies and screening options for IBS and IBD DDW is jointly sponsored by the American Association for t...Clock gene plays role in weight gain, study finds
...rstanding of weight gain could potentially lead to therapies for inhibiting obesity and for treating its effects on health. The study is published this week in the journal Proceedings of the National Academy of Sciences, and is available at: http://www.pnas.org/ "Its been known for some time that there are m...Combining NSAIDs with chemotherapy, radiation may improve cancer treatment
... particularly exciting because one of the standard therapies for most cancers -- chemotherapy -- often has its maximal effect at that stage of the cell cycle," Trask said. "We're hopeful that our results will lead to a clinical trial where we combine celecoxib with chemotherapies for head and neck cancer." T...Natural immune-control system may aid treatment of autoimmune disease and tissue rejection
... tissue as through it were foreign. Conventional therapies for these conditions can have serious drawbacks. Many of them rely on natural substances called antibodies, which wedge inside receptors on immune system T cells. The coupling blindfolds T cells to the presence of foreign or diseased tissue, blunting...IMS updated recommendations on postmenopausal hormone therapy
...mmendations, the term HT will be used to cover all therapies including estrogens, progestogens, combined therapies and tibolone. The previous IMS Statement in 2004 is still valid and serves as a basis for the curr...Pediatric cancer stem cell identified: understanding the origin of ERMS
...nt recurrence and progression, effective long-term therapies must target the self-renewing population of cancer stem cells. The zebrafish is ideally suited for use in targeted chemical genetic approaches to specifically inactivate cancer pathways we have identified in our study. Identifying drugs that inacti...Testosterone may help men with multiple sclerosis
...phase, during which symptoms were monitored but no therapies were administered. After that, each man applied 10 grams of a gel containing 100 milligrams of testosterone to his upper arms once daily for 12 months. "After a year we saw an improvement in cognitive performance and a slowing of brain deterioratio...Burroughs Wellcome Fund awards $14M to support physician-scientists
...titute of Technology Novel biomarkers and targeted therapies for human lung cancer: translation from a mouse model Joseph C. Wu, M.D., Ph.D. Stanford University Molecular and cellular mechanisms of cardiac regeneration Mark Nan Wu, M.D., Ph.D. University of Pennsylvania Identification of novel genes t...Researchers publish first marsupial genome sequence
...progression, as well as explore development of new therapies and preventive treatments. The opossum genome sequence also provides researchers with a fresh perspective on the evolutionary origins of the human genome. It sheds light on the genetic differences between placental mammals, such as humans, mice an...University of Pittsburgh discovers genetic 'shut down' trigger in healthy immune cells
...has been discovered that could one day lead to new therapies against infections, leukemia and other cancers. Results of a University of Pittsburgh School of Medicine study on the mechanism, called a somatic stop-codon mutation, are being reported today in the online journal PLoS ONE, published by the Public Li...