Scientists follow familiar TRAIL to new cancer therapy
A new study identifies a combination therapy that may sensitize human cancer cells to a promisi...pathway called apoptosis, and unfortunately, TRAIL therapy is not effective in cells that have certain defects in apoptotic pathways. Dr. Wafik S. El-Deiry fro...Gene's activity points to more lethal subtype of AML
...he type of damage helps doctors determine the best therapy and an individual's prognosis. In 2005, Bloomfi... that high ERG levels predicted a poor response to therapy in patients whose cancer cells have normal-looking chromosomes. The present study was designed to...UF scientists work to develop simple bladder cancer test
...roteins could lead to the development of effective therapy of bladder cancer, a major cause of cancer death worldwide....Complementary therapy for infertile women may reduce chances of pregnancy
...looked at which women went on to use complementary therapy in the subsequent 12 months. The study was the first large scale prospective evaluation of CAT use in an infertile population. We found that women who went on to use complementary therapies for example reflexology and nutritional supplements dur......stroy tumors like tiny homing missiles. This gene therapy approach is a novel way to attack small tumor metastases that evade current detection techniques and treatments, the researchers conclude in the July 1 issue of Cancer Research, a journal of the American Association for Cancer Research. These fat-d...New research holds promise for protecting cancer patients against infertility
Lyon, France: A promising new therapy for protecting the fertility of women with cancer and auto-immune diseases such as lupus was revealed at the 23rd annual conference of the European Society of Human Reproduction and Embryology today (Tuesday 3 July 2007). Dr. Kate Stern, Research D...M. D. Anderson team identifies new oncogene for brain cancer
...an important candidate for development of targeted therapy to treat gliomas, Zhang says. Gliomas kill about 13,000 people in the United States annually. The possibilities are not limited to brain cancer, Fuller notes, because of the pervasive overexpression of IGFBP2 documented in other cancer types. The...Personalized approach to ovarian stimulation achieves high ART pregnancy rates
...ows a personalised approach to ovarian stimulation therapy for women seeking fertility treatment. Clinical tests demonstrated that when clinicians used the formula (or algorithm) to calculate the best starting dose for each patient, both the number of oocytes retrieved and pregnancy rates rose. Professor F...New approaches to endometriosis treatment -- mouse experiments point the way
...the future it may be able to develop cell-specific therapy for angiogenesis-dependent diseases that will be more effective and less toxic than current treatments.......time clearly represents a potential target for the therapy of allergy. This is currently under investigation, said Dr Nicoletti. David Reading, director of the Anaphylaxis Campaign, said: Food allergy can place an extremely heavy burden on the families affected. We welcome this research and look forward t...Extracting eggs from pre-pubertal cancer patients brings hope for future fertility
... 70% and 90%, and are generally more responsive to therapy than adult cancers. However, the aggressive chemotherapy which is often necessary usually means that children will be sterile in later life. In adult women, the ovaries are stimulated to produce eggs which are removed, fertilised and frozen. ...SNM initiatives supported by inclusions in NAS Report on competitiveness of US chemistry research
...ioisotope R&D needed to advance targeted molecular therapy and other radioisotope needs for the future. The results of a separate NAS study that is reviewing the state of the science for nuclear medicinea multidisciplinary science and medical specialty that uses radiopharmaceutical agents and radiation-det...Breast cancer prognosis runs in the family
...sk factors such as obesity and hormone replacement therapy probably play a role in the incidence and outcome ...tand what is inherited; tumor biology, response to therapy or vigilance of the immune system. ...Support for chromosomal theory of cancer found in cancers' development of drug resistance
...er child for rational drug design once hailed as a therapy that would make drug resistance a thing of the past, has been rendered less useful because the aneuploid nature of leukemia has led to resistance. In fact, he said, this resistance suggests that imatinib is not a highly targeted drug, as advertised, ...Bisphosphonate treatment is associated with jaw bone problems
...n the increasing use of intravenous bisphosphonate therapy for patients with severe osteoporosis, it is important that patients receiving therapy with both established and new formulations of intravenous bisphosphonates be followed carefully for ...Cord blood may preserve insulin levels in children with type 1 diabetes
...e first attempt at using cord blood as a potential therapy for type 1 diabetes. We hope these cells can eithe...as we refrained from using chemotherapy, radiation therapy or manipulating the cells. Since there are a lot more people out there who are banking cord blood th...Penn researchers report that gene therapy awakens the brain despite blindness from birth
...ersity of Pennsylvania have demonstrated that gene therapy used to restore retinal activity to the blind also...ogy in Penn's School of Medicine, shows that gene therapy can improve retinal, visual-pathway and visual-cortex responses in animals born blind and has the po...Can you hear me now? Stem cells enhance hearing recovery
...stem cell transplantation into the inner ear. Cell therapy targeting regeneration of the cochlear fibrocytes may therefore be a powerful strategy to cure sensorineural hearing loss that cannot be reversed by current therapies, state Dr. Matsunaga and colleagues....MIT researchers reverse symptoms in mice of leading inherited cause of mental retardation
... certain enzyme in the brain could be an effective therapy for countering the debilitating symptoms of FXS in children, and possibly in autistic kids as well," said co-author Mansuo L. Hayashi, a former Picower Institute postdoctoral fellow currently at Merck Research Laboratories in Boston. The study iden...Lancet study shows gene therapy for Parkinson's disease is safe and some patients benefit
MANHASSET, NY -- A novel gene therapy technique is safe and may be effective at staving ...ing to calm this hyper-reactive circuit. The gene therapy would be used to reduce symptoms and not alter the underlying disease process. Finding novel therapi...