Stem cell licensing deal positions Toronto as world leader in technology
...stem. Published uses of mesenchymal cells in cell therapy include combating auto-immune and inflammatory diseases (Crohns, juvenile diabetes and rheumatoid arthritis), cancer, heart disease and tissue engineering. While the HUCPVC technology is still in the pre-clinical stage, TRT CEO Dr. Jeffrey Turner s...New amfAR research grants to optimize HIV treatment
...tains HIV that is resistant to both antiretroviral therapy as well as the immune systems efforts to destroy i...users tend not to adhere as well to antiretroviral therapy as those who do not use drugs, the cognitive and biological mechanisms linking drug abuse with poor ...Gene therapy study shows safety and statistically significant improvement in Parkinson's disease
...ancet of positive results from the first ever gene therapy trial for Parkinsons disease and the first report ... both a lack of adverse events related to the gene therapy procedure and statistically significant improvements from baseline in both clinical symptoms and abn...Rutgers, Penn researchers capture research dollars to improve prostate cancer diagnostic methods
...cancerous tissue. Inaccurate grading may result in therapy too weak to treat the cancer or so aggressive that it prolongs therapy and harms healthy tissue. Early results show that where pathologists have trouble distinguishing bet...Remicade data in ankylosing spondylitis show improvement in spinal mobility and spinal inflammation
... In studying the same group of patients, REMICADE therapy also had a positive effect on spinal inflammation, a common and debilitating manifestation of ankylosing spondylitis. In ASSERT spinal inflammation as detected by MRI was examined. Patients receiving REMICADE showed improvement in MRI Activity scor...UD awarded $11M for osteoarthritis research and unique mentoring program for women scientists
...ctives of tissue mechanics, biomechanics, physical therapy and clinical intervention. The program will invo...he departments of biological sciences and physical therapy in the College of Arts and Sciences, mechanical engineering in the College of Engineering, and healt...454 sequencing identifies HIV drug resistance at early stage
... rapidly under drug selection pressure and lead to therapy failure. This retrospective study clearly shows t...esent at the 1% level lead to premature failure of therapy explained Michael Kozal, M.D. the senior author on the study. In the future, hopefully clinicians ca...Cancer stem cells similar to normal stem cells can thwart anti-cancer agents
...ers can and do relapse after apparently successful therapy indicates the survival of a drug-resistant, tumor-initiating population of cells in many types of refractory cancers. Because of the similarities between the way that normal stem cells and cancer stem cells protect themselves, cancer therapies have t...Ultra deep sequencing identifies HIV drug resistance at early stage
...dy was designed to determine if patients that fail therapy early were initially infected with drug resistant ... rapidly under drug selection pressure and lead to therapy failure. This study clearly shows that resistance HIV strains present at the one percent level ca...UVa researchers restore genes in human inner ear cells
...ered a correct form of the gene and created a gene therapy delivery system that successfully transferred the ... with hearing loss. Our results show that gene therapy reagents are effective in human inner ear tissue. Taken together with the results from another group...University of Pittsburgh researchers culture blood-forming stem cells from human fat tissue
... marrow of patients undergoing intensive radiation therapy for blood cancers. They are presenting this ground-breaking research at the Tissue Engineering and Regenerative Medicine International Society (TERMIS) North American Chapter meeting being held June 13 to 16 at the Westin Harbor Castle conference cen...Screening approach leads to discovery of gene linked to breast cancer
...oncogene and shut it down could offer an effective therapy for women whose tumor cells harbor the mutation. The three-stage approach to finding breast cancer genes may be used in other forms of cancer as well, Hahn continues. "Our study provides a framework for integrated genomic methods of oncogene discov...Latest data shows MabThera provides significant, sustained relief from symptoms of RA
...ents." Results following subsequent courses of therapy A total of 1053 RA patients was treated with MabThera with almost 70% of patients followed up for more than two years and 11% for more than three years. The study was conducted in patients who had an inadequate response to treatment with either tumo...Interim analysis of anti-cancer vaccine, BiovaxID, to be conducted
...Standard of Care) remain open and active; the PACE therapy arm of the study be discontinued, with protocol- defined follow-up of all current PACE patients enrolled.Applications for accelerated conditional approval of BiovaxID are planned to be submitted to both the Food and Drug Administration (FDA) and Euro...Other highlights in JNCI, June 12
...patients treated with highly active antiretroviral therapy (HAART) are associated a lower incidence of Kaposi...AIDS since the introduction of HAART in 1996. This therapy usually increases the number of patients CD4 cells, also known as helper T-cells, and reduces the ri...'Lucky 13' as new gene discovery offers further hope for childhood blindness
... announced the start of clinical trials for a gene therapy involving injecting genes into the eye of patients with LCA to restore their sight. The finding of the new LCA gene, based on work funded by the Wellcome Trust and local charity Yorkshire Eye Research, appears in this month's edition of the journal N...ASU research shows connection between testosterone, dietary antioxidants and bird coloration
...he door for future work on nutritional/antioxidant therapy for the hormonally immunocompromised, McGraw added. The interface between diet and health in animals is a fascinating one. But we need a much better understanding of their interactions, as with testosterone, at the molecular level....University of Manchester researchers reveal clues to new genes behind rheumatoid arthritis
...y 40-50% of people do not respond to therapy. This therapy is expensive - 8,000 per patient per year for the newest biologic agents that block the inflammatory mediator TNF - and this work could show whether someone would respond well or not in advance, rather than by costly trial and error." Professor Wor...Studies to find better ways to preserve human eggs, ovarian tissue under way
...rd of care for people who are going through cancer therapy is to use egg donors later on, says Dr. Adelina M. Emmi, reproductive endocrinologist and medical director of MCG Reproductive Laboratories of Augusta. Treatment for leukemia and cervical, ovarian, breast or other cancers often leaves women inferti......enter. To continue to move molecular imaging and therapy innovations from the research laboratory to real improvements in patient care, we need the support of Congress, said SNM President Alexander J. McEwan, who presented the awards during a June 5 Capitol Hill reception. Were extremely appreciative of th...