Burroughs Wellcome Fund awards $14M to support physician-scientists
....D.S., Ph.D. University of Michigan-Ann Arbor Cell therapy for the treatment of alveolar bone defects Michael Z. Lin, M.D., Ph.D. University of California-San Diego Elucidating mechanisms of synaptic plasticity and learning by visualizing and controlling local protein turnover Roger Lo, M.D., Ph.D. U...Inherited genes linked to toxicity of leukemia therapy
...actions to specific drugs. "Such individualized therapy would eliminate the time-consuming trial-and-error approach to finding the right dose for a patient," said Mary Relling, Pharm.D., chair of the Pharmaceutical Sciences department at St. Jude. "When the results of our findings are translated into rout...HIV survival improves if patients stay in care
...vailable on line. "In an era when highly active therapy directed against HIV (the human immunodeficiency virus that causes AIDS) is keeping people alive, understanding the value of regular medical care is crucial," said Dr. Thomas Giordano, assistant professor of medicine infectious diseases at BCM and l...UCLA AIDS Institute researchers find a peptide that encourages HIV infection
... pave the way for the use of such peptides in gene therapy using HIV-based vectors as the delivery method. "Although it may seem counterintuitive to value or even study a peptide that increases the ability of HIV-1 to enter a broad range of human cells, retroviral vectors are currently being explored as ve...FDG-PET imaging clearly predicts lung cancer patients' response to chemotherapy
... the identification of those patients for whom the therapy was futile, he said. The ability to provide an ear...ies one and three weeks after initiation of cancer therapy can predict success or failure of the therapyshould be validated in a larger study in which patients...DNA repair proteins monitored at double-strand break
... novel ways to make cancer cells more sensitive to therapy by blocking their ability to repair double-stranded breaks caused by chemotherapy or radiation. It could also suggest new strategies for enhancing repair of double-stranded DNA caused by radiation, natural oxidants in food or the body and other toxin...Molecule that destroys bone also protects it, new research shows
...cking the receptor for IL-17 could be an effective therapy for RA and possibly for other autoimmune diseases such as multiple sclerosis, colitis, psoriasis and lupus. The effects of an IL-17 deficiency in periodontal disease, however, were unknown, so Gaffens lab set out to investigate. "I predicted the...Enhanced MR-guided focused ultrasound guidelines demonstrate improved efficacy and durability
...nd InSightec, a company that develops non-invasive therapy systems, developed the world's first magnetic reso...f symptoms, and fibroids frequently grow back once therapy is terminated. Summary of Data *Dr. Gee's Poster: "Enhanced MR guided Focused Ultrasound Surgery...Preterm infants with RDS -- surfactant replacement therapies improves neonatal survival
... should carefully weigh their choice of surfactant therapy in their clinical practice." The study presented today was supported by a research grant from Chiesi Farmaceutici of Parma, Italy, manufacturer of Curosurf Intratracheal Suspension, and Dey, L.P., US marketer of Curosurf. "We are pleased to hav...SNM 'capitalizes' opportunity to meet with policymakers, regulators at annual meeting in D.C.
...xcellent opportunity for the molecular imaging and therapy community to get together with policymakers and regulators to discuss issues of shared concern," said SNM President Martin P. Sandler. "This year we have increased the number of educational sessions presented by representatives from the Food and Drug...Estrogen use before 65 linked to reduced risk of Alzheimer's disease
BOSTON -- Women who use hormone therapy before the age of 65 could cut their risk of devel... found women who used any form of estrogen hormone therapy before the age of 65 were nearly 50 percent less likely to develop Alzheimers disease or dementia th...Study shows tight diabetes control does not impact cognitive ability in type 1 diabetes
...rther support for the safety of intensive diabetes therapy and the benefits of maintaining good glycemic cont...abetes. About half of the group received intensive therapy with either an insulin pump or three or more daily insulin injections. The remaining subjects receiv...Manchester to spearhead 8.3 million particle physics project
...-FFAG to be used as a new type of charged particle therapy machine for treating cancer. The reduced size, increased reliability and flexibility of such machines should all lead to lower costs of ownership while delivering more effective therapies." Professor Barlow adds that beams of protons or heavier par...May: Multiple Sclerosis Awareness Month -- latest research is good news
...Not only might it present a significantly improved therapy for patients with relapsing-remitting MS, but it provides a clearer picture of the role that B-cells play in the disease. Its a particularly exciting time and we think meaningful to advancing treatment options for patients." The Phase I trial was p...8 plants from South Africa may hold potential for treating high blood pressure
...e in the world. In South Africa, 21st century drug therapy is used side-by-side with traditional African medicines to heal the sick. While plants have been used in African medicine to treat fever, asthma, constipation, esophageal cancer and hypertension, scientific analyses of the purported benefits of many ...pHLIP, a novel technology to locate and treat tumors
...in that acts like a nanosyringe to deliver tags or therapy to cells, according to a report in the Proceedings of the National Academy of Sciences. The researchers show that, the protein fragment, called pHLIP (pH (Low) Insertion Peptide) can be injected into the abdomen of a mouse, find its way into the bl...Protein found that slows hepatitis C growth in liver cells
...this better is likely to suggest new approaches to therapy for this difficult to treat disease." Hepatitis C chronically infects approximately 170 million people worldwide. The most effective treatment for the virus, interferon-based therapy, eradicates the virus less than 50 percent of the time and causes...Lead-'scrubbing' drug may also improve muscle function in lead-exposed children
...innati (UC) environmental health researchers say a therapy commonly used to remove dangerously high levels of...ldren treated with succimer (SUX-sim-er) chelation therapy showed a 19 percent improvement in their ability to perform moving taskssuch as crossing an obstacle...Antioxidant found in many foods and red wine is potent and selective killer of leukemia cells
...May 4, offer hope for a more selective, less toxic therapy for leukemia. Current treatments for leukemia, s...has the promising potential to be used in leukemia therapy with the advantages of being highly selective against cancer cells. Because this compound is widely ......om damage in MS." Such a drug would be the first therapy specifically for secondary-progressive MS, one of ...ein. They already exist," Bourdette said. Such a therapy can't come soon enough for 36-year-old West Linn, Ore. resident Laura Wieden, who has suffered since...