JCI table of contents September 1, 2005
...hey perceive as painful. Temperature is sensed by thermoreceptors such as TRPA1 and TRPM8. These are cold-sensitive ion channels activated by temperatures under 28 degrees Celcius. The role of TRPA1 in mediating cold pain is controversial. In a study appearing online on August 18 in advance of print publication o...Activation of thermoreceptors mediates raw garlic's burning pungency
...pound and its ability to activate specific protein thermoreceptors in the mouth. The findings are reported in the May 24 issue of Current Biology by a team led by Ardem Patapoutian of The Scripps Research Institute and the Genomics Institute of the Novartis Research Foundation. Despite garlic's popularity, the com...