Rutgers is on the 'NIH Roadmap'
... of science together in a concerted effort to meet these challenges head-on." In this spirit, one of the n...nsible for most biological processes. The study of these molecular machines is particularly relevant to understanding many diseases, such as cancer and metab...UT Southwestern researchers uncover process for sugar-induced fat formation
... "I think one of the most exciting findings of these studies is that a single transcription factor is directly responsible for increasing expression of multiple enzymes for making fatty acids," Dr. Miller said. "This is significant because ChREBP makes sure that glucose is only converted to fat when it...Small business at NJIT's business incubator takes two awards
...illion men in the U.S. are believed to suffer from these problems," said Homan. For more information about Urovalve, please visit: http://www.urovalve.com...Zebrafish may offer researchers powerful new tool for studying innate immunity
... not undergo the complex genetic rearrangements of these adaptive receptors. "The comprehensive definition of the NITR gene cluster in zebrafish reported in this paper represents a significant step toward understanding the mechanisms underlying the transition from non-specific innate immunity to specific ...Medical geneticists elected to Institute of Medicine
...tment to service. Along with many others at NHGRI, these two physicians have been at the forefront of efforts to translate the findings of the Human Genome Project into new strategies for improving human health. The IOM surely will benefit from their membership," said NHGRI Director Francis S. Collins, M.D...Manipulation of epigenome turns off as many genes as it turns on
...ins has discovered. "We don't know what effect all these changes might have, but it's clear that when scien...use extra methyl groups are hanging on to them. If these extra methyl groups could be removed, the thinking has gone, the gene could be restarted and the can...Combination hormone therapy doubles breast density and quadruples risk of abnormal mammograms
... Fred Hutchinson Cancer Research Center, presented these findings today at the third annual International Conference on Frontiers in Cancer Prevention Research hosted by the American Association for Cancer Research."I was surprised by the magnitude of the effect the doubling of breast density associated w...Consuming fruits and vegetables lowers risk of developing NHL
...ir risk of cancer and other diseases. We hope that these findings, in conjunction with continued research and reporting, will help to favorably change the public's eating behavior," said Dr. Kelemen. According to the American Cancer Society, there will be more than 54,000 new cas...Hormone therapy's effect on breast density is not the same for all women, Group Health study finds
...one therapy has raised lots of questions about how these drugs affect breast density and the sensitivity of mammograms," said Aiello. "Having a better understanding of that link and how it relates to various risk factors may help women and their physicians to better evaluate whether HT is the right choice ...High fiber intake reduces estrogen levels in Latina women, according to researchers
..., is to see if a higher intake of dietary fiber in these women leads to a lower incidence of breast cancer. "This study provides clear evidence of an association between dietary fiber intake and circulating hormone levels in postmenopausal Latina women," the researchers note, "and potentially provide......one morphogenetic proteins (BMPs) are expressed in these stripes of cells, implicating BMP signaling (the t...acked articular cartilage. All told, the joints in these mutant mice closely resembled those in people with osteoarthritis, suggesting that BMP signaling is ...Experimental lupus drug may also work against atherosclerosis
... protection against atherosclerosis. For 12 weeks, these mice were fed a diet that was both high in cholesterol and in which 10 percent of calories came from palm oil, one of the vegetable oils most likely to cause atherosclerosis. In addition to the coronary arteries, atherosclerosis also occurred in the ...Dr. Harris receives NIH Javits Neuroscience Investigator Award
...way for better treatments of diseases that disrupt these processes. Her latest grant helps take critical fo...emical messengers called neurotransmitters and how these synapses change in size and number so information can be learned and remembered. "There have b...Gene linked to greater risk of heart disease in type 2 diabetes
...thway, reducing risk of heart attack and stroke in these patients." An estimated 18 million people in the ...l had type 2 diabetes. In addition, nearly half of these subjects also had heart disease, as shown by heart catheterization indicating more than 50 percent b...Lag-3 gene dampens immune responses by controlling regulatory T-cell function
...ification of a specific molecule on the surface of these cells that we can block represents an exciting new... We're actively pursuing the best strategy to test these findings in patients." Drake is co-author of the paper. In mouse studies, the rese...Gene-altered mouse is model for rare autoimmune syndrome
...t to determine the initial cause of the disease in these complex animal models, he said. Zhuang and his colleagues did not set out to produce a mimic of Sjgren's syndrome in their studies. Rather they were exploring the role of a regulatory protein, called Id3, that previous studies in Zhuang's labor...Study in Royal Society journal on how relationship status influences sex ratios
...ated from your enemy, the eavesdropper. Neither of these conditions implies the other, as easy examples sho...ines (like waves on a slinky spring). We find that these waves can be converted to heat quite efficiently and are likely to be important for heating the sola...Promising new preventative treatment option for population of men at high risk of prostate cancer
...gainst the onset of prostate cancer. "Fortunately, these results offer a promising new preventive approach to prostate cancer treatment. A chemopreventive agent like toremifene is a first step toward the possibility of stopping prostate cancer before it starts and gives patients and doctors a chance to fig...Mice thrive despite massive genetic makeover
..., or is some of it potentially disposable? "In these studies, we were looking particularly for sequence...deed have minimal if any function." To see what these non-coding sequences were doing, the investigators took a brute-force approach. "To use an architec...Genetically modified parasite lets researchers probe immune system's memory
... never had Leishmania and were given injections of these T cells fought off the parasite more effectively t...ay need to look at generating large populations of these memory T cells at the time of vaccination," says study coauthor Stephen Beverley, Ph.D., the Marvin ...