NYU and MSKCC research provides model for understanding chemically induced cancer initiation
... the properties of carcinogen-DNA lesions. Current thinking in the field of chemical carcinogenesis is that the mutation-prone, or error-free processing of such carcinogen-damaged p53 genes by DNA repair proteins and DNA and RNA polymerases can determine whether these lesions ultimately contribute to the deve...Understanding biological foundation of human behavior critical to improving laws
...g about development of the mind and the biology of thinking is growing at a tremendous rate," Jones said. "The main significance of this article is that it demonstrates how the legal system can be more effective in pursuing its goals if it integrates life science and social science perspectives on behavior." ...Childhood deficits in the cerebellum may be linked to adult alcoholism
...nclined to act on their emotional impulses without thinking about the consequences. That's generally what we see in people with alcoholism and other addiction disorders." Since the cerebellum is an important structure for movement, Manzardo hypothesized that if deficits in the cerebellum were indeed contribu...Leptin: A 'missing link' between obesity and diabetes?
...more to the obesity-diabetes link than the classic thinking that if you eat too much sugar, you'll get fat and get diabetes -- and that if you don't get diabetes, it's only because you're making more insulin to keep up with the sugar," says Myers. "There's something else contributing. Now the challenge is to ...High cholesterol levels accelerate growth of prostate cancer
... effect. "Our study opens up a new paradigm in thinking about how cancer might be controlled pharmacologically by manipulating cholesterol," says Freeman. "Our data support the notion that cholesterol-lowering drugs -- which are widely used and fairly safe -- might be effective in prevention of prostate c...Scientists identify new model Of NK cell development
...lood. In other words, they had a hunch traditional thinking about the origin of human NK cells might be wrong. In building a case to support their beliefs, they first identified the NK precursor cell, then, they measured the number of the precursors in different parts of the body. Through flow cytometry, they...Neuroscientists locate 'imaginary' colors
...white field. Thanks to their synesthesia, went the thinking behind the task, synesthetes would be able to identify the embedded shapes more quickly than normal controls. Most of the study's synesthetes (five of six) did indeed outperform control subjects in this task. But synesthetic colors were not as "stro...'Mandela's Paradox' may show that osteoporosis propensity starts in pre-teen years
...an apparent paradox, which has implications on our thinking about osteoporosis, the roots of which may well lie in the childhood years. It's obvious that intervention is becoming increasingly important during the growing years as this is the period when physical activity and nutrition have the most impact. It...Understanding natural killers could lead to new hepatitis treatments
...or damaged tissue. The findings offer a new way of thinking about this important class of immune cell, which is responsible for the inflammation and cell death in the liver due to hepatitis. Hepatitis can be a reaction to viruses, parasites such as malaria or other infections. Learning to "call off" the NKT c...New technology, new approach to help heart and lung patients awaiting transplants
...lts in myocardial recovery. By changing our way of thinking and addressing heart failure in its earlier states...AD usage gains increasing acceptance, a new way of thinking may change the way doctors use these assistive devices. Ventricular assist devices stabilize adults ...UW-Madison gains two new stem cell programs
... in stem cell biology and be exposed to the latest thinking in the field. It will be a tremendous asset for the university and our already established programs." Svendsen stressed that both new programs will operate in close conjunction with the existing UW-Madison Stem Cell Research Program, a program estab...Prenatal cocaine exposure exerts subtle effects on schoolchildren
...f behavior problems, that they might have problems thinking and learning," said UF neonatologist Marylou Behnk...areas of the brain more involved with planning and thinking strategically - the regions that cocaine, in theory, would most likely affect. In this next arm of t...Environmental technologies earn award for PNNL
...l undertaking that has the potential to influence thinking and design elsewhere." THE SOUNDS OF SALMON Researchers at PNNL and the National Marine Fisheries Service have developed a sophisticated yet simple underwater acoustic system that reveals the behavior and fate of migrating juvenile Chinook salmon ...Hopeful results from interrupted Alzheimer's vaccine study
... regular vital sign exams, and tests of memory and thinking ability. All of the injections will be in the first year, with the second year for follow-up exams. U-M is not yet recruiting participants for this study, but is taking names of those people who might want to be contacted when recruitment opens. U-M...African-Americans and Caucasians have similar emotional brain activity when seeing African-Americans
...he forehead and eyes, and has been associated with thinking in words about emotional experiences; it also is associated with inhibiting behavior, impulses and emotions. "This region is especially active when you add the verbal label to the face," Lieberman said. "The people who show the most activity in the ......ow these structures operate but also our hubris in thinking our biology and nature is unique....Molecular spies illuminate drug resistance proteins
...inds and how it moves across so that one can start thinking about designing inhibitors of these molecules," Mchaourab said. "Whether it's resistance to infectious diseases or resistance to chemotherapy, the goal is to silence these proteins by designing inhibitors that bind tighter than the chemotherapeutic ...Scientific Integrity text adds website support to new edition
...ikewise, it provides the tools to promote critical thinking in use of that information. Taken together, these elements foster the hope that the book will set the stage for lifelong learning in scientific integrity and the responsible conduct of research," says Macrina. Scientific Integrity: Texts and Cases ...To stop evolution: New way of fighting antibiotic resistance demonstrated by Scripps scientists
...e genes that drive evolution, an innovative way of thinking because scientists have more often understood evolution as the force that drives genes. What underlies evolution is mutation -- changes in the DNA. "Mutations are the fuel for evolution," says Romesberg. Because of the potential ha...... offers an important contribution to a new wave of thinking in genetics: that not all human disease states are due to alterations in DNA sequence. Dr. Terry Magnuson - Sarah Graham Kenan professor, chairman of genetics and director of the Carolina Center for Genome Sciences in UNC's School of Medicine - led t...