NIH awards new $14.5 million, five-year grant to the Scripps Research Institute
... able to stick a molecule under a microscope, look through the eyepiece, and, to paraphrase the late physicist Richard Feynman, just look at the thing. A lot of biology can be understood simply by seeing what a molecule looks like, but the scale of biological molecules is extraordinarily small. All but th...DNA sequence controls expression of gene involved in cancer
...iptionally. One way bcl-2 levels are controlled is through an adenine and uracil-rich sequence of nucleotides in the 3' untranslated region of the bcl-2 mRNA. This sequence, called the AU-rich element, or ARE, recruits a number of proteins that destabilize the bcl-2 mRNA, resulting in its degradation. A re...32 new grants made for innovative technology R&D
...f up to $56.9 million, if all projects are carried through to completion. The ATP supports projects that indu...e application-specific integrated circuits (ASICs) through direct-write lithography. Nanospectra Biosciences, Inc. (Houston, Texas) The Seamless Detecti...Yearling horse auction to benefit equine research
... the care and welfare of the horse from conception through its older years to its interaction as a grazing animal with the land. The research objectives are to develop pastures and pasture supplements that improve the reproductive efficiency of mares, optimize growth in the young horses, enhance athletic per......human species. That means archaic humans didn't go through the same population shrinkage and thus must have spread their lice to Homo sapiens sometime after 50,000 years ago. Rogers speculates contact occurred 25,000 or 30,000 years ago. ...Endangered frogs coexist with fungus once thought fatal
...was suggested that some unknown disease had spread through the populations. In 1998, the fungus Batrachochytrium dendrobatidis was identified from sick and dead frogs and, since then, several lines of laboratory based evidence have suggested that B. dendrobatidis is to blame for the dramatic frog decline...A treatment, not a cure: Calcium silicate neutralizes an acidic stream
... only way to successfully combat stream acidity is through improved air quality. Until that happens, we are exploring short-term methods of restoring water quality to sensitive sites." Symptoms of acidified streams include a drop in pH, calcium, and dissolved inorganic carbon and an increase in metals like ...HHMI researchers Richard Axel and Linda Buck win 2004 Nobel Prize
...y one of these criteria, we would have had to sort through thousands more genes," said Axel. "This saved seve...ar receptor proteins in other species by searching through libraries of DNA from these species. Odorant receptors of humans, mice, catfish, dogs, and salamande...Research team develops nonhuman primate model of smallpox infection
...pox, a devastating disease, was eradicated in 1979 through the efforts of the World Health Organization (WHO). Currently, infectious variola is known to exist only in two WHO-sanctioned repositories, one in Russia and the other at the Centers for Disease Control and Prevention (CDC) in Atlanta. However, th...New Stanford center probes nanoscale material
...ion director, to train middle-school teachers and, through them, inspire tens of thousands of young students. Modeled after programs at Cornell and Rice universities that work with high school teachers, the Stanford program trains teachers who work with younger students. "By the time [students] reach high sc...Stanford researchers establish center for physics-based simulations of biological structures
...n toolkit, as well as streaming online instruction through the Stanford Center for Professional Development....Daphne Koller named MacArthur Fellow
...analyzing the yeast genome, where they helped sift through staggering amounts of gene-expression data to tease out useful information. A recent paper by her research group, published in Nature Genetics, applied a probabilistic model to identifying modules of co-regulated genes and identified regulatory roles...Stanford cooling tool may improve performance of athletes, soldiers
... a method for cooling that maximizes heat transfer through the palms of the hands. The idea is to engorge con...of the palm of the hand [by circulating cool water through a closed system on which the palm of the hand rests], which cools the blood in the hand's vascular h...Pine cones lead to a fundamental change in clothing
...ally open up, so that air from the outside can get through the material to cool the wearer. When the wearer s...rial that is not porous so that rain can never get through from the outside, whether the spikes are open or closed. The technology of the material is bei...Plants provide model for new shape-changing materials
...flight. An analogy would be a hawk that is soaring through the sky, suddenly sees its prey, and changes its s...s are producing a revolution in engineering design through the application of biological principles to the design of new autonomous engineering systems," Leo s...Intelligent clothing inspired by pine cones
...ally open up, so that air from the outside can get through the material to cool the wearer. When the wearer s...rial that is not porous so that rain can never get through from the outside, whether the spikes are open or closed. The technology of the material is being des...Good news: As you age, leg blood vessels adapt so you can still exercise without fainting
...d for on-site or telephone interviews, can be made through APS with Mayer Resnick (cell: 301.332.4402, mresnick@the-aps.org) or through Stacy Brooks at 301.634.7253 (sbrooks@the-aps.org). From Oct. 6 (2 p.m.) to Oct. 9, the onsite phone...Running not swimming or biking is best kind of loading exercise for childrens bone growth
...ustin, Texas (Oct. 6, 2004) -- Mechanical loading through exercise builds bone strength and this effect is m...hone interviews during the meeting can be arranged through APS Communications Officer Mayer Resnick (cell: 301-332-4402, mresnick@the-aps.org ) or through Sta...NIH funds first nationaL SNP genotyping center at Broad Institute
.... Results will be accessible to the investigators through a secure database integrated with a suite of data management and analytic tools for analysis of correlations among variants and with disease phenotypes. Because investigators use different technologies based on the scales and configurations needed, a......mentary to the detailed simulations we're creating through Folding@Home." Basic thermodynamics dictates that ... profile of the energy states a protein progresses through while it folds. When this energy profile is plotted on a multidimensional graph, Clementi and her co...