Novel antiviral technology inhibits RSV infection in mice
...ining nanoparticle and gene silencing technologies thwarts attacks of respiratory syncytial virus (RSV) -- a virus associated with severe bronchitis and asthma, an animal study by University of South Florida researchers found. The study was reported in the January 2005 issue of the journal Nature Medicine ....Ancient immune defense mechanism is no match for HIV-1
...search also reveals exactly how HIV-1 successfully thwarts this rare form of immunity in vertebrate cells. However, elucidation of the mechanism HIV-1 uses to protect itself provides some critical insight into a potential vulnerability within the HIV-1 molecule. Identification of what might be a long sought...Gene thwarts some pathogens, gives access to others, could save crops
A single gene apparently thwarts a disease-causing invader that creates a fuzzy gray coating on flowers, fruits and vegetables. But the same gene provides access to a different type of pathogen. A Purdue University plant molecular biologist and his collaborators in Austria and North...Researchers discover inhibitor of infection by HPV
...lly manipulating access to the cells. Carrageenan thwarts this process by attaching to HPV and preventing its entry into cells. Christopher Buck, lead author of the study and post-doctoral fellow at the National Cancer Institute, searched for candidate inhibitory compounds by looking for substances that w...Diversity promotes cooperation among microbes
... fluorescens has identified a novel mechanism that thwarts the evolution of cheats and broadens our understanding of how cooperation might be maintained in nature and human societies. The new findings are reported by Michael Brockhurst of the University of Liverpool and colleagues at the Universit Montpellie...Squirrels winning at outwitting trees' survival strategy
...uccessful, their hoarding and gorging on the cones thwarts the trees' ability to cast seeds and reproduce.So the battle continues. Over the years, the trees devised a strategy called masting in which they unpredictably every few years produce an overabundance of cones. Boutin, the study's lead author, sai...Weill Cornell team identifies potential new cancer drug target
...IAP). Scientists had already discovered that XIAP thwarts the apoptotic impulse by putting the brakes on key enzymes called caspases. XIAP is also known to be highly active in cancer cells, but it is found in relatively low levels in healthy cells. How XIAP inhibits caspases is known, but how XIAP induces N......me lung cancers. This suggested that LKB1 normally thwarts tumors from forming. Mutated versions may be unable to act as a brake on cancer. To find out, the investigators ran a series of experiments in mice with a defective form of a gene called Kras, which drives the formation and growth of lung cancer. T...