Unravelling new complexity in the genome
...alternative splicing differently in nervous system tissues compared to other mammalian tissues, says lead investigator Professor Benjamin Blencowe of the Banting and Best Department of Medical Research and Centre for Cellular and Biomolecular Research (CCBR) at the University of Toronto According to Blenc...Abnormal fat metabolism underlies heart problems in diabetic patients
...se they very rapidly determine which lipids are in tissues and blood. "Shotgun lipidomics provide a precise way to measure changes in heart lipid content," says first author Xianlin Han, Ph.D., assistant professor of medicine. "We found a dramatic depletion of cardiolipin in heart muscle as early as five day...Sugar and spice and everything nice: Health differences in newborn girls and boys
...psies were collected at the end of the period. All tissues were analyzed for adenosine adenosine triphosphate (ATP; the main energy source of the heart), creatine phosphate (CP; a readily available stored form of energy), lactate, and hydrogen ion (H+) concentration. Histidine concentration, which protects ...Innovative tagging technique may help researchers better protect fish stocks
...n artificial taga stable isotope of bariuminto the tissues of mature female fish just before spawning. That chemical tag is then passed to the females offspring and becomes a chemical signature within the ear bones (otoliths) of the next generation of fish. Researchers can then track the dispersal of the tag...In limiting life span, study finds booming bacteria innocent
...level, then that energy isnt available to maintain tissues and organs. However, we found no effect on the animals longevity even when their bacteria are taken from one extreme to the other. Nevertheless, he added, the bacterial infestations seen in the aged flies have to be a quality of life issue....Role of thyroid hormones in slumber under investigation at Rutgers
...neck and increases cellular activity in nearly all tissues of the body by acting inside cells. Thyroid hormones do so much more than regulate weight. Were really just beginning to learn the true extent of how these hormones impact our overall health, Martin says. The research underway at Rutgers-Camden...UF, French scientists seek test to detect gene doping in athletes
...aced with a myriad of uncertainties, such as which tissues in the body to sample and how to distinguish a doped gene from a naturally occurring form of the gene. Ultimately, the test will compare how many copies of the EPO gene are found in an athletes body to levels found in the average person who has not ...How cells change the pace of their steps
...ergo an orchestrated migration to form functioning tissues and organs. Poorly regulated cell motility during embryonic development may result in some neurological diseases and birth defects such as cleft palate of the mouth. UCSDs new findings may eventually be used to better understand and possibly treat su...Discovery of new protein could provide new understanding of male fertility
... first E1, UBE1L2 might have a specialized role in tissues and in particular in the testis. Going back to the previous analogy of the Federal Reserve Bank, this result shows that UBE1L2s main client banks may be in the testis and that UBE1L2 controls many of the protein degradation processes in that organ. ...Scientists prove that disputed Korean stem cell line comes from an unfertilized egg and not cloning
...les. If careful genetic and functional analysis of tissues derived from human pES cells show them to be safe and effective, then pES cells might represent a favorable source for tissue replacement therapies, says Dr. Daley. ...New strategy for treating allergic disorders
...nd foreign substances and begins to attack our own tissues and organs. In other cases, the immune system responds mistakenly to harmless substances, such as the house dust mite, milk products, or pollen. This inappropriate immune system reaction to contact with such substances (allergens) is called an allerg...Einstein researchers' prototype vaccine could provide improved protection against tuberculosis
...ion, significantly fewer bacteria persisted in the tissues of secA2 mutant-vaccinated animals than in the tissues of animals vaccinated with BCG. And compared with BCG, animals vaccinated with the mutant vaccine ha...Discovery in plant virus may help prevent HIV and similar viruses
...hey are activated in the plant," he said. "In some tissues the genes appear to be turned on in the same place. But, for example, in the flower, one gene is expressed in one particular place and the other gene is expressed in a different place." The key question for researchers is how blocking the function ...Rare example of Darwinism seen in action
... placenta is a complex organ of maternal and fetal tissues that nourishes the developing fetus in the uterus. Most mammals, excluding marsupials like the kangaroo and the koala, have a placenta. Because of the placenta, a developing embryo remains longer inside the mother (in marsupials, early development...Cell damage caused by brushing may help keep gums healthy
...might be another positive aspect of brushing. Many tissues in our bodies respond to mechanical stress by adapting and getting stronger, like muscles. We think the gums may adapt to this mechanical stress by getting thicker and healthier. Its the no pain, no gain theory the same as exercising. The research ...American Chemical Society's Weekly PressPac -- July 25, 2007
...ate new nerve cells from easily available cells or tissues would provide a more convenient and attractive approach to stem cell therapies, the new study notes. The researchers exposed immature mouse muscle cells (myoblasts) growing in laboratory cell cultures to neurodazine, a synthetic small molecule. Af...Research teams uncover risk genes for multiple sclerosis
... between autoimmune diseases that affect different tissues in the body, including type 1 diabetes and rheumatoid arthritis, said David Hafler, MD, the Jack, Sadie and David Breakstone professor of neurology at Harvard Medical School and Brigham and Womens Hospital, another of the consortium study authors. Th...Risk genes for multiple sclerosis uncovered
... between autoimmune diseases that affect different tissues in the body, including type one diabetes and rheumatoid arthritis, says David Hafler, the Jack, Sadie and David Breakstone professor of neurology at Harvard Medical School and Brigham and Womens Hospital, and one of the studys authors. This study wil...Nottingham biosciences million pound injection
...ly porous scaffold structure, which encourages new tissues to form. The unique scaffold mechanism also assists the delivery of stem cells and drugs without compromising their effectiveness. This offers a substantial opportunity to deliver a cure to patients with bone, liver, heart or nerve tissue defects. ......oduced in excess, increase inflammation in various tissues and organs. The results, by William L. Smith, Professor and Chair of Biological Chemistry at the University of Michigan, Ann Arbor, and colleagues, may help in designing new anti-inflammatory drugs with fewer side effects than the ones currently avai...