Tag: "tolerance" at biology news
Good news: As you age, leg blood vessels adapt so you can still exercise without fainting
...s target interventions aimed at improving exercise tolerance
in older adults, he said. Next steps and funding: The researchers will be conducting similar experiments in women (both on estrogen replacement and not). They plan to study the mechanisms underlying age-related changes in vascu...
New genetic tools provide clues to the effects of exercise and diet on obesity, diabetes
...ent existing molecular models for improved glucose tolerance
with exercise intervention in pre-diabetic individuals, he noted. On the proteomics side, the researchers analyzed gene expression and protein profiles from muscle of lean and obese and morbidly obese individuals. "This combination of genomi...
New technique targets pesticide-resistant insects
...an 500 species of insects and mites have developed tolerance
to chemicals 3 including pesticides regarded as being environmentally benign. Dr Robin Gunning said the technology is likely to be of particular importance to the third world, where pesticide resistance and chemical overuse on crops is a major pr...
Using fruitflies to examine alcohol tolerance
both promotes and facilitates the increasing consu...olerance. Findings suggest that rapid and chronic tolerance
are partially distinct in mechanistic terms, as well as genetically distinguishable, from one anothe...
New method studies living bacterial cells
...he surface adherence of the biofilm cells promoted tolerance
to the chromium and reduced its toxicity level. Finally, when the cells made the transition from the planktonic state to the biofilm state, the scientists observed changes in the concentrations of many transition metals required for bacterial life. ...
Tiny exosomes extracted from donor cells may be 'magic bullet' for drug-free transplants
...tic cells may hold the key to achieving transplant tolerance
the long-term acceptance of transplanted organs w...e. Considered the "Holy Grail" of transplantation, tolerance
means a recipient's immune system fully accepts a donor graft without immunosuppressive drugs and wi...
Ancient creature fossilized by the bacteria that ate it
... the ocean bottom. The bacterias tolerance
of heat and its taste for sulfur make it a good candidate for life on the early Earth, and genetic studies have suggested that archaebacteria may have been one of the first forms of life 3.5 billion years ago. The sample the Ohio State scientists fou...
Community living causes bacteria to diversify
...ey do not have as individuals, including increased tolerance
to antibiotics. The new findings suggest biofilm growth may provide another key advantage. Using a laboratory model, the UI team found that when biofilm communities were established using a small number of identical bacteria, a remarkable degree of d...
Researchers discover new way to boost grain crops' drought tolerance
...t the development of technology that increases the tolerance
of grains crops to drought by decreasing the amoun...which may have already begun. "Increasing drought tolerance
in crops is highly valuable to U.S. and world agriculture now, and will be even more critical as our...
Studies in Royal Society journals include stress in birds and depletion of medieval fish stocks
...s are generalists. These features confer relative tolerance
to extinction for plant species. But tolerance
is not immunity, and it is essential to conserve pollinators that are generalised, including bumbleb...
University of Texas at Austin researchers identify drug-tolerance mechanism in flies
...s that were first-timers. The flies that developed tolerance
also had increased activity of the slo gene. The...rparts. The researchers have since found that this tolerance
lasts for more than seven days. "These findings show that very short exposures to drugs have very l...
NC State gets $1.59M grant to map genome of parasitic worm
... of chemical nematicides "The root-knot nematode's tolerance
to pesticides is quite robust, so in many cases the defenses against root-knot nematodes are more toxic to vertebrates than to the nematodes," he says. "There are also non-target effects of pesticides to worry about, like the groundwater and other en...
Healthy mix of GI tract microbes are key to preventing allergies and asthma
... and you upset the immune system's balance between tolerance
and sensitization." To test their hypothesis, Huf...gnore it a reaction we call tolerance. The key to tolerance
is an immune cell called a regulatory T cell." Discovered just a few years ago, regulatory T cells a...
Parents' attitudes to sperm donation still some concerns about being open
...r stigmatisation of male infertility, as increased tolerance
may influence parents' openness. We also need large-scale follow-up studies investigating DI parents' and children's choices and concerns." The UK study UK researchers interviewed 46 families from a London clinic who had a 4 to 8-year old child con...
Lost tolerance is a grave Omenn
...xpressed in the thymus and helps establish central tolerance
and prevent organ-specific autoimmunity. In the presence of AIRE, peripheral self-antigens are presented and autoreactive T cells are eliminated whereas in the absence of AIRE, such clones survive and lead to self-reactivity. The authors propose th...
Alcohol's effects on gene expression in the central nervous system
...sitivity to the effects of alcohol, development of tolerance
to the effects of alcohol, development of alcohol dependence, and alcohol withdrawal severity," he said. "For the average reader, knowing which genetic profiles might contribute to excessive alcohol drinking could be used to identify risk factors th...
Source of molecular triggers in cutaneous T cell lymphoma identified
...promoting Treg development may be useful to induce tolerance
in autoimmune disease and transplantation,"...
Leptin: A 'missing link' between obesity and diabetes?
...tes and its precursor conditions, impaired glucose tolerance
and insulin resistance. A person who has so-called "pre-diabetes" has overly high levels of blood sugar, as the beta islet cells in his or her pancreas struggle to make enough insulin. (Insulin ushers sugar into cells so it can be burned as fuel.) P...
World's largest rainforest drying experiment completes first phase
...biggest surprise noted thus far has been the great tolerance
that this forest presented in the face of the severe drought that was created. As the moisture stored in the soil that sustained the forest during prolonged dry seasons was depleted in the dry plot, the trees simply absorbed water from deeper in the ...
Joslin Diabetes Center scientists find genetic defects
... which researchers elsewhere had shown to have the tolerance
defect, with diabetes-resistant controls. They looked for regions where the data from the DNA chips and the genome scan converged. Overlap would indicate the regions and genes that affect tolerance. In the mice with diabetes, two findings emerged -- ...
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