Yale dean addresses biggest environmental threats in new book
...ial use. Over 40 percent had a complete absence of toxicity data. Species loss today is estimated at as much as 1,000 times the natural or normal rate that species go extinct. Excessive nitrogen production and over-fertilization has contributed to over 150 dead zones in the oceans. ...DFG presents the 2006 MAK and BAT value list
... as well as inhalation, essentially contributes to toxicity at the workplace. This classification was examined for 15 other substances and in one case it was removed (aminobutane). The section entitled "BAT values, BLW and EKA" includes seven changes and new entries. Exposure equivalents for carcinogenic su...Computational model simulates AZT metabolism in mitochondria
...scientists to better understand the metabolism and toxicity of the HIV/AIDS drug zidovudine (azidothymidine, A... side-effects. Our job is to model these proposed toxicity mechanisms to see which ones could actually lead to the mitochondrial defects found in AIDS patients...Mosquito spray increases toxicity of pyrethroids in creek, study finds
...roup of insecticides can mix with and increase the toxicity of existing pesticides in the environment, accordi...ty of California, Berkeley. While the increase in toxicity was relatively modest, the effects from the interaction of chemicals were unexpected, the researcher...... observations gathered by McClenachan's group, the toxicity of hawksbill turtle meat has decreased from the 17th through 20th century, most likely due the turtles eating fewer of the toxic sponges. The changing ratio of sponge species will ultimately affect the landscape of coral reefs. The scientists say ...UW-Madison research part of international mercury conference
...oom C: A UW-Madison researcher has found that fish toxicity notices in Wisconsin are often ineffective and largely fail to inform consumers about the dangers of mercury-contaminated fish. Maria Powell, a research associate at UW-Madison's Lafollette School of Public Affairs, explored fishing cultures among...New research points toward mechanism of age-onset toxicity of Alzheimer's protein
...e opportunities to attenuate beta amyloid-mediated toxicity by manipulating the activity of these factors," says Dillin. New model for neurodegenerative diseases Half of all people who reach age 85 will likely be affected by Alzheimer's disease, and the onset age usually around 75 is almost the same f...Scientists discover age-regulated cellular activities that protect against protein aggregation
...n appears to cause Alzheimer's disease-showed that toxicity from protein aggregation is "drastically reduced" ...that the amount of aggregates would correlate with toxicity in these worms, but there was no correlation." "This second finding is clearly a shift in paradi...Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial
... The next step for the FAK siRNA-DOPC liposome is toxicity testing. "So far it appears to be very well-tolerated," Sood says. "We hope to develop this approach for clinical use in the future." In addition to ovarian cancer, FAK is overexpressed in colon, breast, thyroid, and head and neck cancers. ...Adverse effects of chemotherapy may be under-reported
..., and there will be few incentives for longer term toxicity studies. [] Without careful long term tracking of ...verse effects, there is a risk that very important toxicity events will occur unnoticed."...New company will seek drugs against diabetes and cancer
...icular drug, the drug could potentially lessen the toxicity of high sugar in diabetics, according to Baranski. Using fruit flies for drug screening is fast and inexpensive because the flies' short life spans and small size allow quick turnaround and multiple simultaneous tests in a small space. Furthermore,...New methods for screening nanoparticles
...scribed in a review article on carbon nanoparticle toxicity in a special section of the August 23, 2006, issue of the Journal of Physics: Condensed Matter devoted to developments in nanoscience and nanotechnology, now available online. Nanoparticles may have different physical, chemical, electrical, and opt...Over the edge: New therapeutic strategy takes advantage of stressed cancer cells
...ly targeting cancer cells while exhibiting minimal toxicity in normal cells. The research is published in the September 2006 issue of the journal Cancer Cell, published by Cell Press. Most cancer cells exhibit overproduction of reactive oxygen species (ROS), which is thought to provide favorable conditions f...Using microbes to fuel the US hydrogen economy
...s by which Thermatoga neapolitana can avoid oxygen toxicity during hydrogen production. "Understanding the oxygen tolerance of Thermatoga neapolitana will facilitate its practical application to produce hydrogen from agricultural resources," van der Lelie said....Raloxifene reduces breast cancer risk in postmenopausal women at all risk levels
...efine the lowest limit of risk, the point at which toxicity associated with use of raloxifene outweighs the benefits," he said. Dr. Lippman stressed that he cannot comment on how raloxifene in this study measures up to tamoxifen use in general. He explains that although these findings come on the heels of t...Metals in China: Protecting the environment
...vances in the understanding of metal behaviour and toxicity in soils." In the first instance, a series of fie...nvironments in China, to examine the behaviour and toxicity of copper and nickel in Chinese soils. This data will be combined with data already collected in Eur...Metals in China: Protecting the environment
...vances in the understanding of metal behaviour and toxicity in soils." In the first instance, a series of fie...nvironments in China, to examine the behaviour and toxicity of copper and nickel in Chinese soils. This data will be combined with data already collected in Eur...Georgetown leads effort to study safety of 'alternative' tobacco products
...ratory and Georgetown researchers will analyze the toxicity of the products; investigators at Arista and Roswell will study the product design; and researchers at Harvard and Roswell Park will consider the perception of consumers to these products, and will examine tobacco company documents, including testing......ez also observed that following the pollution, the toxicity of the nematodes does not increase but is variable. Gene regulation Additionally from a genetic viewpoint, nematodes quickly adapt to environmental factors such as the ambient temperature. For example a temperature rise from 16 to 24 degrees Cels...Texas researchers casting for answers to stop algae problem in Texas lakes
...alga organism?" The team already discovered that toxicity can be removed by adding nutrients such as nitrogen, phosphorus, vitamins and trace metals. Roelke said more study is needed about golden alga life cycles because applying a treatment to massive bodies of water is not possible. "But perhaps some fo...