Tag: "toxicology" at biology news

New center to map DNA of key lab mice

...ng research findings to population analysis and to toxicology testing. These studies will also influence the dev...ops," said Olden. "Technology is accelerating both toxicology and environmental health research. NIEHS will lead the way in these two disciplines to make predicti...

Gene therapy approach reverses diabetic neuropathy in animal model, Pitt study finds

...proach to a clinical trial we must first carry out toxicology studies with the HSV vector to support its highly safe design. The vector itself is highly defective and incapable of reproducing itself," noted Dr. Goss. "Most of us have been exposed to herpes simplex virus and we need to be concerned that in a pat...

Genetically endowed worm may substitute for rodents in some toxicology testing

... Freedman, an associate professor of environmental toxicology who has worked with C. elegans since graduate school, now seeks to apply this extensive knowledge about the roundworm's biology to answer questions involving toxicology. "The idea is to quickly screen chemicals with C. elegans so you don't have t...

New comparative toxicogenomics database

...centralized, integrated, and curated molecular and toxicology data from diverse organisms for scientists worldwide. "It is becoming increasingly well accepted that many diseases involve interactions between environmental factors and genes. We integrate key data from diverse species, such as gene sequences, chem...

UAlbany CNSE enters NanoBio alliance with Albert Einstein College of Medicine

...cal implementation drug discovery and delivery toxicology detection and cure medical devices and components demonstration and deployment Under the terms of the agreement, CNSE and Albert Einstein will provide their respective faculty and scientists with access to their respective facilities. In addition,...

VCU researchers identify networks of genes responding to alcohol in the brain

...l Miles, M.D., Ph.D., a professor in pharmacology, toxicology and neurology, who also has an appointment in VCU Life Sciences' Center for the Study of Biological Complexity. Gene expression refers to how much a given gene is "turned on," eventually leading to more or less protein being produced by that particul...

NTP roadmap for the future, celebration of 25 years

...gy will also provide a long-term vision that moves toxicology away from an animal-based enterprise, including developing non-mammalian models. "A Roadmap for the Future" defines how NTP will integrate new methodologies with proven approaches to "test smarter." Background: For more than 25 years, the NTP...

Water quality a major focus of $14 million grant to the University of Arizona

...d A. Jay Gandolfi, a professor of pharmacology and toxicology at The University of Arizona in Tucson and director of UA's SBRP. The program involves about 70 researchers and spans five UA colleges and 10 departments. Previous environmental studies done by UA's SBRP, which began in 1989, developed technology to ...

Virginia Tech wins $2.7 million grant to protect people from malaria

...th initiative. Jeffrey R. Bloomquist, professor of toxicology and pharmacology in the department of entomology at Virginia Tech, is principal investigator of the three-year project. Collaborating Virginia Tech researchers are Paul R. Carlier, associate professor of chemistry, Sally L. Paulson, associate profess...

Prescription pain patch abuse blamed for increase in deaths

...d researcher, Bruce Goldberger, Ph.D., director of toxicology and an associate professor in the departments of pathology, immunology and laboratory medicine and psychiatry in UF's College of Medicine. Patients who are prescribed the patch must be made aware of the potential dangers of misuse, Goldberger added. ...

Nanotubes inspire new technique for healing broken bones

...o clinical trials, Haddon plans to investigate the toxicology of these materials and to measure their mechanical strength and flexibility in relation to commercially available bone mimics....

Industrial contaminants spread by seabirds in High Arctic, new Canadian study shows

...led by Dr. Jules Blais, professor of environmental toxicology at the University of Ottawa, will be published July 15 in the journal Science. Other team members are Marianne Douglas from the University of Toronto, D.McMahon and Linda Kimpe from the University of Ottawa, Bronwyn Keatley from Queen's University, a...

New Scripps Oceanography project to study sediments and ecosystem restoration in Venice lagoon

...ts into several different aspects of environmental toxicology and environmental quality assessment," said Deheyn. "It will be extremely interesting and unique to address the many different angles of a single problem." Scripps scientists and SIOSED research areas include: Dimitri Deheyn: bioavailability and t...

A fatty acid found in milk may help control inflammatory diseases

...h Institute and chair of the food microbiology and toxicology department; James Ntambi of the biochemistry department; and Dale Schoeller of the nutritional sciences department. His collaborators on the recent study include Guangming Li, a postdoctoral fellow in animal sciences; David Barnes, a former assistant...

Sperm stem cells closer to being like embryonic stem cells

...udy. "It is a larger animal, it's often better for toxicology and physiology studies, and its behavior is more in tune with that of humans in many cases. It's also important to be able to produce pluripotent rat cells, because we would then have another animal model to test stem cell-based therapies, such as co...

Toxicology-on-a-chip tool readies for market

...t-up businesses. The MetaChip (metabolizing enzyme toxicology assay chip) mimics the effects of metabolism in th... relatively slow pace of technology development in toxicology and clinical safety evaluation that could be used in early phases of drug development continues to h...

Food additive inhibits longevity enzyme in yeast, increases cell toxicity, new study finds

...ecomes important," said Martyn Smith, professor of toxicology at UC Berkeley's School of Public Health and princ... sciences and lead author of the paper, noted that toxicology testing routinely focuses on an agent's ability to cause DNA mutations, chromosome alterations, or c...

Experimental TB drug effective against resistant and latent mycobacterium tuberculosis

...g animal experiments that examine pharmacology and toxicology in preparation for an investigational new drug (IND) application to the Food and Drug Administration, which they hope to submit in a few months, so they may proceed to clinical trials. If the drug lives up to the promise in human trials that it sh...

ACS weekly press package May 8, 2006

...key nutrients The poisons within: a new focus for toxicology Electrifying sewage Cleaner gas flaring for the...u ARTICLE #2 The poisons within: a new focus for toxicology Chemical Research in Toxicology Every Crime Scene Investigation (CSI) fan knows that toxicology is ...

DFG presents the 2006 MAK and BAT value list

...nment to another group. As no data on reproduction toxicology was available, the substances that were previously listed in section IIc of the MAK and BAT values list have also been assigned to group D, "No conclusive evaluation possible at this time". In the group of carcinogenic chemical compounds, o-toluidi...

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(Date:5/23/2013)... , Automated conserved noncoding sequence (CNS) discovery reveals ... , Within the genome of each species, there ... change in position and sequence over millions of years, ... these evolutionarily stable sequences, so-called conserved noncoding sequences (CNSs), ... or the condensation of chromosomes, but the function of ...
(Date:5/23/2013)... Rollins School of Public Health at Emory University, ... Technology, have received a $4 million grant over ... Emory University (Health and Exposome Research Center: Understanding ... center grant awarded in the United States. ... National Institute of Environmental Health Sciences (NIEHS) of ...
(Date:5/23/2013)... undergo surgery or harsh treatments because science fails ... forms of the disease. Researchers at Case Western ... developing technology that allows patients to safely choose ... or take drastic measures. , The project is ... of biomedical engineering at Case Western Reserve and ...
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