Genetic repair mechanism clears the way for sealing DNA breaks
...ve and under continuous assault from environmental toxins and reactive cellular metabolites. A means of repairing DNA damage is vital to maintaining the integrity of the genetic blueprint. When these repair processes go awry, cells can malfunction, die or become cancerous, so researchers would like to know......d fish and seafood, or even inhalation of airborne toxins from sea spray. The impact on public health and regional economies is intensifying as the frequency and duration of harmful bloom occurrences continues to grow. Diaz and other researchers will be building on a previous CICEET project that has alread...New biochip helps study living cells, may speed drug development
...els. In nature, some of the most potent venoms and toxins work by blocking these channels, including the venom of certain snakes and strychnine. Porterfield's chip is technically classified as a "cell electrophysiology lab-on-a-chip." The device is further described in an article in the journal Sensors a...Researchers report initial success in promising approach to prevent tooth decay
...vity issue, Shi and his colleagues began attaching toxins to the homing region of antibodies. They borrowed the concept from immunotherapy, an area of cancer research in which toxin-toting antibodies are programmed to kill tumor cells and leave the nearby normal cells alone. Despite some success in killin...Different strategies underlie the ecology of microbial invasions
...nt. The findings show that the release of chemical toxins is superior as a resident strategy to repel invasions, whereas the release of parasites is superior as a strategy of invasion....U of M study shows treatment of periodontal disease does not decrease risk for preterm birth
...d bleed. Untreated, bacteria build up and produce toxins that irritate the gums and stimulate an inflammatory response that breaks down the gum tissue. As the tissues are damaged, gums begin to separate from the teeth, forming "pockets" between the teeth. Eventually, the attachment of the tooth and its su...Accelerating loss of ocean species threatens human well-being
...s sewage and recycles it into nutrients, it scrubs toxins out of the water, and it produces food and turns carbon dioxide into food and oxygen." But in order to provide these services, the ocean needs all its working parts, the millions of plant and animal species that inhabit the sea. The strength of the...Lungs try to repair damaged elastic fibers
...nsplants. COPD develops as a result of exposure to toxins such as cigarette smoke, resulting in inflammation to the small airways and destruction of elastic fibers within alveoli. The patients suffered from emphysema. The team used hyperpolarized magnetic resonance imaging (MRI) to characterize the region...Accelerating loss of ocean species threatens human well-being
...s sewage and recycles it into nutrients, it scrubs toxins out of the water, and it produces food and turns carbon dioxide into food and oxygen." But in order to provide these services, the ocean needs all its working parts, the millions of plant and animal species that inhabit the sea." The study analyzed...Tarantula venom and chili peppers target same pain sensor
...r species may have evolved the ability to use such toxins to target heat- and pain-sensing neuron receptors,... generate noxious sensations," Julius said. "These toxins are incredibly useful for understanding how ion channels of the nervous system work. They give us cl......ciences. The study in rats found that cone snail toxins named RgIA and Vc1.1 can treat nerve hypersensitiv...n, stroke, traumatic brain injury, shingles, nerve toxins and electrical or other damage to peripheral nerves. Sometimes, doctors are unable to find a cause. ...New study finds on/off switch for septic shock
...elated mortality. Bacterial infection, notably the toxins that are part of the bacterial cell wall, stimulate the inflammatory response which can spin out of control. Sepsis progresses swiftly from chills, fever and shallow breathing, to dilated and leaky blood vessels, a lack of blood supply in the body's ...Exposure to dioxins influences male reproductive system, study of Vietnam veterans concludes
...nmental studies of the impact of dioxins and other toxins on the male reproductive system. Previous research was largely based on animal models, Dr. Gupta said, noting that the urgency of further research is underlined by a rise in disorders of the male reproductive tract over the past several decades. Th...Tips from the Journals of the American Society for Microbiology
...peutic method using human antibodies to neutralize toxins was found to prevent Clostridium difficile-induce...dies (HuMAbs) capable of neutralizing C. difficile toxins A and B. Researchers then tested anti-toxin A HuMAb CDA1 alone and in conjunction with anti-toxin B...Sandia research to focus on early detection of harmful algal blooms
...p a technology that can successfully detect deadly toxins from harmful algal blooms (HABs). The funding is p...egion. Current methods for detecting the poisonous toxins characteristic of the blooms are cumbersome, require either expensive reagents or animal testing, or...Smokers who cut back on cigarettes may negate benefit through 'compensatory smoking'
...still experience significantly greater exposure to toxins per cigarette than light smokers, according to a n...ienced a four- to eight-fold increased exposure to toxins per cigarette as compared with light smokers. Compensatory smoking occurs because smokers are tryi...Study finds oysters can take heat and heavy metals, but not both
...g extra that they can invest in protection against toxins that may be in the water. An increase in seasonal temperatures would be an additional problem. The current environmental stresses on oysters may in fact be partially responsible for recent outbreaks of disease that have already decimated many easte...Study helps explain why botulinum toxin is so deadly
...blocking ability of the seven individual botulinum toxins for decades, says botulinum expert Edwin Chapman, UW-Madison professor of physiology and a Howard Hughes Medical Institute investigator. "A major question is how the toxin enters neurons," he says. The research was a close collaboration with Ray Stev...Nano design adjustment may help find, clear some water contaminants
...d to a new approach to locate and remove dangerous toxins such as perchlorate and nitrates from the environm...eloping materials that sense the presence of these toxins and remediate them. While 0.2 nanometers seems an insignificant distance, it could mean there's a ......inum neurotoxins are among the most deadly natural toxins in the world. They act by first attaching themselves to receptors on the surface of neurons. The toxins then insinuate an enzyme into the neuron that degrades key proteins required for neurons to communic...