A Jekyll-and-Hyde enzyme's role in Alzheimer's
...eimer's disease (AD). They found that the enzyme's transformation from Jekyll to Hyde may be due to abnormal activation of the brain's mechanism to compensate for the damage from such diseases. This compensatory mechanism may also function in normal aging, they said. In their article in the December 8, 2005, issue ...Russian River coho recovery project seeing first hopeful signs of success
...oho planted this year will undergo a physiological transformation to prepare them for life in the saline waters of the ocean. These "smolts" will begin a downstream migration that Obedzinski and other UCCE biologists will be monitoring, with in-stream traps, to generate a coho head count and provide information ab...Why the Amazon rainforest is so rich in species
...t at very different rates, and their extinction or transformation is mostly determined by the ecology and biology of each species. We want to discover more about why some species survive and multiply, while others remain static or become extinct." Around 40% of the world's species can be found in the tropical areas...Model identifies genes that induce normal skin cells to become abnormal
...nfluence of the tumor cell microenvironment on the transformation of normal skin cells, as well as on genetic triggering mechanisms and signaling pathways that could be targeted for novel therapeutic strategies to inhibit the spread of melanoma," Hendrix said. Metastatic cancer cells are characterized by increased...Scientists unpick genetics of first 15 minutes of life
...sity of Bath. "Sperm DNA has to undergo a complete transformation when it arrives in the egg cell so that it can properly join with the female pronucleus to form a new genetically complete the beginning of a new life. "A slight mutation in the HIRA gene means that life does not even get started. "Amazingly we still...Sudden change in social status triggers genetic response in male fish, study finds
... ("eyebar") appears across his face. This physical transformation signals to males and females alike that he's the t... colleagues were the first to observe this diurnal transformation among dominants. "During the experiment, I would remove the dominant male one hour before the light...Research: removal of dominant rivals causes male cichlid fish to undergo remarkable transformation
...ubordinate male fish underwent a radical and rapid transformation when more dominant males were removed. "When we took dominant cichlid males from an experimental tank, subordinate males started becoming dominant themselves in as few as two minutes," Burmeister said. "Their colors -- blue and yellow -- got much bri...AAAS science literacy project 20th anniversary, Oct. 17-19
...nce concepts-natural selection or conservation and transformation of energy, for example-but also to understand the nature of science, the importance of evidence in scientific argument, and the kinds of questions science can and cannot address. All of these ideas are at the core of what it means to be science liter...NIH launches major program to transform clinical and translational science
...today announced a new program designed to spur the transformation of clinical and translational research in the United States, so that new treatments can be developed more efficiently and delivered more quickly to patients. "We are truly at a crossroads in medicine," Zerhouni said. "The scientific advances of th...Brain regulates initial stages of sex change in social fish
...experiences an array of behavioral changes and the transformation of her sex organs to male. In the study, CBN researcher and Georgia State University biology professor Matthew Grober, PhD, CBN and Georgia State post-doctoral fellow Michael Black, PhD, and researchers Jacques Balthazart, PhD, and Michelle Baillien,...Climate change transforming Alaska's landscape
... research with Alaska Pacific University, says the transformation of Alaska's landscape corresponds with an increase...dscape in the long term. Klein says that Alaska's transformation is another piece of evidence in the climate change puzzle. "The bottom line is that a change is happ...Tissue rigidity promotes tumor progression
...b tissue organization, thereby promoting malignant transformation of a tissue."...Markers of brain cell development may help success of stem cell transplants
...med in development before rapid cell migration and transformation begins. "These 'interstates' are called Bergmann glia or glial fibers. They serve as guidance for the neuronal cells to migrate," Dr. Yu says of the network that is maintained in the adult brain despite the fact that mature neurons don't really chang...Virginia Tech research, graduate program focus on interfaces
...educational model will help drive an institutional transformation at Virginia Tech and beyond. The program will support at least 27 graduate students during the next five years. "As part of EIGER, we will develop a new graduate-level course that will actually teach students how to do interdisciplinary research in s......c and colleagues will study chemical reactions and transformation of mercury in flue gases of coal-fired power plants. They will then develop and validate a mathematical model to predict mercury emissions. "If we can understand fundamentals of the catalytic reactions that are promoted by solid surfaces present in c...Reversal of role for a viral protein associated with the development of lymphoma
...he lymphatic system. They begin with the malignant transformation of a lymphocyte in the lymphatic system. The American Cancer Society estimates that 63,740 people in the U.S. will be newly diagnosed with lymphoma by the end of 2005. HHV8, originally linked to Kaposi's sarcoma the most common cancer among AIDS pat...Key process in gene regulation occurs in blood platelets, Univeristy of Utah researchers find
...eus (anucleate). Scientists long have thought the transformation of pre-mRNA into mature mRNA--called splicing--happens only in a cell's nucleus. But using stem cells from human umbilical cord blood to engineer the precursor cell that forms platelets and platelets isolated from the blood of study subjects, the Uta...Trapping genes that control flower development
...ant Cell. The gene trap technique involves genetic transformation of Arabidopsis plants with a reporter gene whose a...sed by Drs. Irish and Martienssen involved genetic transformation of Arabidopsis plants with the reporter gene -glucuronidase (GUS) lacking an external promoter seque...Immune system's distress signal tells bacteria when to strike back
...point key early steps of this lethal process. The transformation starts when a weakened host tries to boost its defenses against any possible invasion. The host's T cells release chemical signals that activate the immune system. One of those signals, interferon-gamma, is intercepted by a protein, called OprF, fou...Woods Hole Research Center plans controlled burn in Amazon rainforest
Fire is an important agent of transformation in the Amazon landscape. Every year, low intensity fires burn thousands of square miles of Amazon forest. To study the effects of these fires on the forest, and the forests' ability to recover from repeated burning, Woods Hole Research Center scienti...