New mechanism found for neurodegenerative effects of amphetamines in mice
... throughout mammalian life -- is the catalyst that transforms amphetamines into free radical products that react with oxygen in the body to enhance the formation of highly toxic reactive oxygen species. These toxic forms of oxygen are implicated in neurodegenerative diseases such as Alzheimer's and Parkinson's ...The unseen impact - could adult diseases be caused by food and chemicals before birth?
... cross the placenta, and whether or not the foetus transforms these chemicals into a more toxic form that results in damage to DNA. With 10,000 volunteers to be recruited in the Born in Bradford part of the project over the next few years, the researchers also hope to follow those children through, to see how t...A case of mistaken molecular identity
...lses sent to the brain. "Rhodopsin takes light and transforms it that's its function," said Levin. To demonstrate molecular mimicry in the retina, Paveto extracted rhodopsin from cow's eyes. Through a series of tests, the team showed that cow rhodopsin, which is similar to the human protein, reacts with antib...Microbes convert 'Styrofoam' into biodegradable plastic
...nd and Germany, utilized pyrolysis, a process that transforms materials by heating them in the absence of oxygen, to convert polystyrene the key component of many disposable products into styrene oil. The researchers then supplied this oil to P. putida, a bacterium that can feed on styrene, which converted th......his on-going investigation of the brain and how it transforms visual stimuli into conscious experience. His paper, "Visibility, visual awareness, and visual masking of simple unattended targets are confined to areas in the occipital cortex beyond human V1/V2," is available in the Nov. 8 issue of the weekly jour...JCI table of contents November, 2005
...arly gene product of tumorigenic adenovirus, which transforms cells in culture and forces terminally differentiated cells to re-enter the cell cycle, the authors identified a transcriptional signature in myotubes, then dissected the mechanisms responsible for activating the individual genes in the signature. Fi...New look at DNA hints at origin of ultraviolet damage
... different from the mechanism in single bases that transforms the energy into heat in less than a trillionth of a second," Kohler said. "Eventually, the energy does turn into heat, but the important point is that the energy is retained within the molecule for much longer times," he added. "This can cause all ki...Earth from Space: unique Arctic landscape surveyed by Proba
...re kilometres, is a haven for Arctic wildlife that transforms for five months each summer from frozen tundra to fertile wetlands. The Delta is located at the end of the 4400-km-long course of the Lena River, one of the longest rivers in the world. It is an important breeding ground for many migratory birds and ...Good connections are everything
...ts with a disordered pattern, this initial pattern transforms into an ordered one on a very short time scale, a property which applies even to an infinite network. In both cases, the tiny fraction of highly connected nodes is sufficient to spread the relevant information over the whole network. Such networks m...US/African project deciphers deadly parasite genome
...sts better understand how the parasite malignantly transforms cattle white blood cells into cancer-like cells th...a, whichcauses tropical theileriosis in cattle and transforms macrophages,monocytes and B-lymphocytes. That study was led by scientists at theWellcome Trust Sange...Researchers get first peek at amyloid's spine
...of Nature . In each disease, a different protein transforms into the misfolded threads known as amyloid fibrils. Scientists believe that the various proteins share a common underlying feature that explains how they assemble into the persistent fibrils that can accumulate in the brain and other tissues. "To d...Gene keeps neural cells on correct developmental path
... protein directs the complex network of genes that transforms an embryonic stem cell into a mature nerve cell, say Howard Hughes Medical Institute (HHMI) researchers. This new study, published in the May 20, 2005, issue of the journal Cell, may be among the first to track a set of genes from stem cell to differ...Embryonic stem cells treated with growth factor reverse hemophilia in mice
...nal without apparent immunological rejection. This transforms them into possible candidates for cellular transplantation into the liver."...Improved molecular switch could serve as sensor, medical tool
...e. When we introduce this switch into bacteria, it transforms them into a working sensor." As in their earlier experiments, Ostermeier's team made a molecular switch by joining two proteins that typically do not interact: beta-lactamase and the maltose binding protein found in a harmless form of E. coli bact......e a human, so is walking going to be what suddenly transforms the hominid body?" he asks. "We're saying, no, walking won't do that, but running will." Walking cannot explain most of the changes in body form that distinguish Homo from Australopithecus, which when compared with Homo had short legs, long forea...Endurance running may be key to evolution of human body form
...e a human, so is walking going to be what suddenly transforms the hominid body?" Bramble asks. "We're saying, no, walking won't do that, but running will."...Findings challenge Darwinian theory
...me-sized claws, but somehow, only one of the claws transforms into a larger crusher claw as the lobster grows. "The genetic program that makes a crusher claw is triggered by one claw being used more than the other. But if one side isn't stimulated enough, the program that makes a crusher claw never gets started...Diabetic damage to eyes, heart, nerves, kidneys may be explained by controversial theory
...y. Like glycolysis, the sorbitol pathway transforms NAD to NADH, but only at a small fraction of the l...lysis makes pyruvate as well as NADH, and pyruvate transforms NADH back to NAD. The sorbitol pathway doesn't make pyruvate, so the NADH it makes has to be recycle...