Tag: "transfusion" at biology news
Variant CJD -- Prion amplification breakthrough brings new insights and hopes for a blood test
... can pass variant CJD prions on to others by blood transfusion
and there are also fears that the disease might also be spread by certain kinds of surgery. One way to protect blood recipients from this threat is to screen blood donations for prions, but efforts to develop such a test have proven difficult, part...
Study produces conflicting findings on the use of anti-anemia drug in cancer patients
...id not show that darbepoetin significantly reduced transfusion
risk. "While the study was not specifically de...times used in the U. S. to treat anemia and reduce transfusion
risk in patients not on chemotherapy, these results are of concern to the research and clinical canc...
After 2 years, study shows Revlimid patients live longer and remain transfusion free
...erm durable results and help them to achieve blood transfusion
independence and remain transfusion
free. "These landmark data demonstrate that Revlimid, in many cases, eliminates all signs of the c...
Eculizumab is well-tolerated and shows significant improvement in PNH patients (Ph III)
...reported outcomes and measures of anemia including transfusion
requirements. During the study, eculizumab was found to be well tolerated with an adverse event profile similar to that of placebo patients in the Phase III TRIUMPH study. Further, no serious adverse events were deemed probably or definitely related...
The New England Journal of Medicine reports data on eculizumab for the treatment of PNH
... primary endpoints were achieved, including median transfusion
rate and haemoglobin stabilization over six months. The median transfusion
rate was reduced from 10 units per patient with placebo to 0 units per patient with eculizumab (p ...
New procedure safer for detecting fetal anemia
...es with severe anemia are treated with fetal blood transfusion
while still in the uterus. Dr. Seaward co-led the study with Dr. Oepkes from Leiden University Medical Centre in the Netherlands, and believes the research will lead to an important and exciting shift in practice whereby physicians will be able to...
Prion find points way to test for human 'mad cow' disease
...econdary transmission from human to human by blood transfusion
or surgical procedures could become a big problem," he continued. "This result is an important step toward a practical biochemical test that will determine how common variant CJD is, and keep contaminated blood and organs from spreading it further." ...
JCI table of contents, May 18, 2006
...Approximately 1 in every 600 persons who receive a transfusion
of a plasma-containing blood product develops transfusion-related acute lung injury (TRALI) within 6 hours of the transfusion. As such, TRALI has emerged as the leading cause of death from a blood transfusion. The mechanisms underlying this condition...
Interdisciplinary team develops guidelines for treating severely injured patients
...eumonia, blood sugar control, nutritional support, transfusion
thresholds, and sedation. The team chose to cover aspects of care for which practices vary the most and those that have the greatest potential to influence patient outcomes. The scientific team is part of a collaborative, NIGMS-supported initiative c...
Pall blood filtration technology removes prions that can cause TSEs
...Dr. Coker explains, "Transmission of vCJD by blood transfusion
is a serious threat and prion reduction by filtrat...mptomatic for many years and no one knows how many transfusion
recipients may be receiving infected blood. There is no reliable test available to determine the pr...
Interim Aranesp data suggest major response in anemic patients with MDS
...se, achievement of target hemoglobin, incidence of transfusion
and patient reported fatigue. Sixty-nine percent ...iliter [g/dL] increase from baseline hemoglobin or transfusion
independence). Sixty-seven percent of patients achieved the target hemoglobin level of 11 g/dL. Ni...
Pall Corporation presents approach for speeding vaccine production to Shanghai conference
...eds of customers in biotechnology, pharmaceutical, transfusion
medicine, semiconductor, water purification, aerospace and broad industrial markets. Total revenues for fiscal 2005 were $1.9 billion. The Company headquarters is in East Hills, New York with extensive operations throughout the world. Visit Pall at...
Improved blood safety measures from Pall can increase platelet availability
...ilability of safe platelets is a fundamental blood transfusion
challenge and can be especially problematic in tim...nated platelets would be significantly reduced and transfusion
medicine specialists would no longer have to make a trade-off between clinical safety and availabili...
Studies validating performance of Pall prion reduction technology presented at AABB
... because of the potential for transmission through transfusion
from asymptomatic donors. Pall Corporation (NYSE: PLL) is presenting research results further validating the performance of its Leukotrap Affinity Prion Reduction Filter System, which was CE marked with a 99.9 percent prion removal efficiency in May...
Blood conservation strategies take center stage at Emory University Hospital forum
...the discretion of individual physicians. However, transfusion
practices vary greatly based on knowledge level an...iovascular Anesthesiologists. While guidelines for transfusion
are not clearly defined, it is evident that blood needs to be used more judiciously, especially in p...
Breakthrough technology from Pall increases platelet availability and safety
...lood centers will be able to provide hospitals and transfusion
services with Acrodose SM Platelets, a transfusion-ready therapeutic dose of platelets that is both leukoreduced and bacteria tested with a highly sensitive culture based method. In turn, hospitals can reduce their handling costs by eliminating the ...
Discovery links blood cell defect to common lung disorder, leads to novel treatment
...als given red blood cells replete in SNOs, whereas transfusion
of red blood cells deficient in SNO raised pressures, the team reported. To examine the relevance of the findings to human disease, the researchers compared the level of SNO in the blood of patients with pulmonary hypertension to that of healthy peop...
Interim data suggest major response with Aranesp(R) in anemic patients with MDS
...re presented for all 100 patients for incidence of transfusion
and patient reported fatigue and 90 patients were ...ual to 2 g/dL increase from baseline hemoglobin or transfusion
independence). In the previously erythropoietin treated group (n=33), 36 percent experienced an eryt...
New results validating Pall prion reduction filter disclosed at ISBT Congress
Athens, Greece (July 4, 2005) -- Safety in transfusion
medicine is an ongoing challenge to blood services...e, and minimize risk of transmission through blood transfusion
was presented here at the International Society of Blood Transfusion Congress. At the "Safety in Tr...
NC woman is now insulin-free after series of three islet cell transplants
...in a day or two. As in Annie's case, more than one transfusion
of islet cells may be needed. "Islet transplantation has been in the experimental stage for more than 25 years," said Dr. Gores. "It's considered a treatment rather than a cure, although in several recent studies, islet cell transplantation has been...