Tag: "translation" at biology news

UCI awarded $40 million to establish regional biodefense and infectious disease research center

... heart of the center, a central goal is the timely translation of our findings into products and other applications to detect, prevent and treat the diseases and bioagents," he said. "We've worked hard to get to the point of getting this award, but there won't be much of a rest. We're ready to move ahead with th...

Stem cell research in New York City receives pivotal boost from The Starr Foundation

...aintain stem cells for research and ultimately for translation into clinical medicine." "This generous financial commitment from The Starr Foundation will allow our three institutions to move ahead decisively and together on many important fronts in stem cell research, fields of study that hold great promise for...

Stem cell research at Weill Cornell, The Rockefeller University, and Sloan-Kettering

...y Clinical Trials Unit will be vital assets in the translation of basic stem cell biology into clinical medicine. The Rockefeller University is widely recognized as a center of innovation in basic research to improve the scientific understanding of the biology of stem cells. Rockefeller scientists provided the ...

Columbia dedicates new 300,000 sq. ft. Irving Cancer Research Center

... Dr. Dalla-Favera, fostering collaboration and the translation of new ideas from clinical observations to new therapeutic options, from bedside to bench," said David Hirsh, Ph.D., executive vice president for research and professor of biochemistry and molecular biophysics at Columbia University. "As we move to...

Scientists find microRNAs regulate plant development

...s the mRNA into smaller pieces, thereby preventing translation of the protein it encodes, and thus inhibiting or "silencing" gene expression. mRNAs corresponding to several regulatory genes that mediate auxin responses contain short stretches of sequence that are complementary to microRNAs, and therefore have be...

Washington University chosen as NIH Program of Excellence in Nanotechnology

...edical and materials scientists Dissemination and translation of nanotechnology developments As an example of h...rmed in the Program, with emphasis, ultimately, on translation to treat pulmonary and acute vascular inflammation and injury in humans. "We're excited by the man...

A kiss that binds

...meaningful since FMRP is believed to regulate mRNA translation in the brain, and identifying the mRNA targets of ...y, they show that the association of FMRP with the translation machinery (in brain polyribosomes) can be competed out with kissing complex RNA, an important findin...

Ancient enzyme guides healthy eating in mammals

...ress response by modifying a second protein called translation initiation factor 2 (eIF2a). Mice without the normal complement of GCN2 in the brain failed to exhibit an aversion to imbalanced food, the researchers reported. The protein inactivation also led to a decline in modified eIF2a in a key part of the bra...

African-American women less likely to undergo genetic testing than white women

...d genetics presents a substantial challenge to the translation of advances in human genetics into improvements in health. Although empirical evidence of racial disparities in the utilization of BRCA1/2 counseling provides important information about this challenge, it only further highlights the need to move for...

Carnegie Mellon and U. of Pittsburgh create tool to understand neuron rhythms, learning

...se-resetting curve (PRC) of living neurons. Like a translation key, a PRC dictates how a given neuron will change its routine firing pattern in response to input from other neurons. "You can think of neurons firing like people clapping after a performance. People don't start out clapping in unison, but then som...

Yale scientists find microRNA regulates Ras cancer gene

...binding to the message for Ras and likely inhibits translation of the Ras protein," said Slack. "The microRNA does not revert a mutated Ras to normal; instead it acts like a brake on an accelerated Ras." Lung cancer currently has a poor prognosis with less than 15 percent of patients surviving five years. The lu...

Cooperation is keya new way of looking at MicroRNA and how it controls gene expression

... came out that showed that microRNA could suppress translation in certain Drosophila (fruit fly) genes if those genes contained sequences complementary to the microRNA's sequence. But finding the targets of these microRNA proved difficult, and by the turn off the century, only a few had been identified. When the...

JCI Table of Contents, March 1, 2005

...iversity report a novel approach to interfere with translation of IRS-1 and IRS-2 specifically in the liver in order to determine the roles of these molecules in the metabolism of normal mice. Knockdown of both IRS-1 and IRS-2 led to symptoms of the metabolic syndrome, including insulin resistance, glucose into...

Timing is everything: First step in protein building revealed

...dicate that it must be very loosely associated for translation [protein building] to begin." To monitor what was happening to eIF1, the researchers tagged it and a related part of the ribosome with different fluorescent chemicals. When two fluorescently labeled molecules are near one another, the fluorescent che...

EB and IUPS - Where cures of tomorrow can be seen in the science of today

...years, on how advances in genetics, especially the translation of the human genome, can lead to better understanding of healthy states as well as why and how many diseases develop and how they can be better diagnosed, treated, and prevented. Sponsoring societies of Experimental Biology 2005 are: American Associ...

Scientists reveal molecular secrets of the malaria parasite

...specific to the mosquito stage, indicating delayed translation of transcripts from these genes. Hall says that gene-regulation motif "is particularly interesting because these proteins, expressed early in the mosquito, are the target of transmission-blocking vaccines" —that is, vaccines which raise antibodi...

NYU chemists create DNA translation machine

...ersity have developed a device that allows for the translation of DNA sequences, thereby serving as a factory for assembling the building blocks of new materials. The invention, described in the latest issue of Science magazine, has the potential to develop new synthetic fibers, advance the encryption of infor...

Experimental Biology/Congress of the IUPS meets March 31 - April 6 in San Diego

... focus on how advances in genetics, especially the translation of the human genome, lead to better understanding of healthy states as well as of why and how diseases develop and how they can be better diagnosed, treated, and prevented. When: Experimental Biology 2005 meets April 2 - 6. The IUPS Congress mee...

Carnegie Mellon scientist develops way to deliver promising genetic tool into living cells

... ultimately become. By infusing GPNAs to block the translation of specific RNAs, researchers also could "down-regulate" the production of disease-related proteins. Scientists could use GPNAs to temporarily inhibit production of different regulatory proteins in cells, which could prove especially helpful in model...

UT Southwestern initiating trials in humans for ricin vaccine

... as an outgrowth of their cancer-therapy work. The translation from discovery to clinical testing has moved rapidly with support from the National Institutes of Health (NIH) and the "incredible efforts of a talented and dedicated group of scientists and research associates," Dr. Vitetta said. The genetically eng...

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(Date:10/17/2014)... Why do male ... reproduce? And why are there two sexes anyway? These and ... the research journal Molecular Human Reproduction published today ... University Bielefeld has compiled this special issue on sperm competition. ... copulate with several males in quick succession – chimpanzees are ...
(Date:10/16/2014)... Researchers at William and Mary,s Virginia Institute of ... from the Environmental Protection Agency to identify the ... and to develop tools to help local governments ... project depends critically on a dataset of tidal-marsh ... 1970s. Only with this historical baseline can today,s ...
(Date:10/16/2014)... respiratory tract infections and worldwide claims the lives ... and Ghent University have succeeded in developing a ... infection. , Xavier Saelens (VIB/UGent): "We discovered ... for the development of a novel approach to ... in numerous small children and elderly people." , ...
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