Tag: "transplant" at biology news
Chinese medicinal compound stops formation of cysts in polycystic kidney disease in lab
...at would be the first treatment, other than kidney transplant
or frequent dialysis, for one of the most lethal o... swell, and the person moves to either dialysis or transplant
in order to survive. That means a treatment that slows down the development of cysts does not have...
The stem cells that weren't there
...ity to produce its own insulin. One solution is to transplant
tissues called the islets of langerhans, small masses within the pancreas containing the beta cells that normally secrete insulin. Islet transplants have already been performed experimentally, but typically fail after a few years in a patient's body....
XDx to present recent success with AlloMap molecular expression testing
...est, currently used to detect the absence of heart transplant
rejection instead of routine invasive heart muscle...t cytomegalovirus-induced immune responses in lung transplant
patients. "These data continue to validate the outcomes of the Cardio Allograft Gene Expression O...
LIAI scientists make important finding on cytomegalovirus transmission
...r persons who are immuno-compromised such as organ transplant
recipients or AIDS patients. Ware said, "The main importance of these experiments is identifying the critical molecular targets controlling virus persistence, and two ways in which we can modulate immunity in vivo with the desired result of blockin...
UF scientists identify cancer virus' genetic targets
...n addition, the disease occurs in about one in 200 transplant
patients in the United States. Other as yet unidentified genes could be affected by the microRNA of Kaposis sarcoma virus, according to Mark Samols, a graduate student of molecular genetics and the papers lead author. But by knowing at least some o...
'Nondanger' signal lowers immune reactions
...trolling those responses could potentially protect transplant
patients from rejection episodes or could relieve symptoms of autoimmune diseases such as rheumatoid arthritis and lupus. The study, which was performed in mice, appeared in the May 15 issue of the Journal of Immunology. Researchers from The Chi...
Stem cells may look malignant, not act it
...rchers then studied mice who underwent bone marrow transplant
and developed the same cancers as the women. When ...mor cells. Some patients who undergo bone marrow transplant
later develop secondary cancers because of the high doses of radiation and chemotherapy they receive...
Description of a gene implicated in the development of Fanconi anemia and predisposition to cancer
...e is to select an embryo that is compatible with a transplant
donor. Furthermore, identification of the responsible gene is indispensable for the future application of gene therapy. The researchers have studied the function and mutational spectrum of the FANCD2 gene, one of thirteen genes implicated in Fanc...
Studies to find better ways to preserve human eggs, ovarian tissue under way
...re are insufficient numbers of donors for those on transplant
lists today, another piece of the puzzle is developing techniques for growing organs. In fact, he is collaborating with scientists at Yale University and the Georgia Institute of Technology to regenerate blood vessels and pancreatic substitutes, noti...
Pre-cancerous blood diseases can be products of their environment
...rs and blood cells. Unexpectedly, they reported, transplant
studies revealed that this disease was caused by t...that cant support them, it will be as if you didnt transplant
them at all." ...
A faster way to recover from chemotherapy and marrow transplant
...p patients who undergo chemotherapy or bone marrow transplant
for leukemia and other cancers recover their immun...drug. Currently, patients undergoing bone marrow transplant
must wait for marrow from a matched donor to replenish their stem cells and reproduce the full array...
Gene's activity points to more lethal subtype of AML
...dings mean that these patients require a stem-cell transplant
or other aggressive therapy, and that patients with low ERG activity can be treated using standard therapy. The research confirms a 2005 study led by the same Ohio State researchers in a completely independent set of patients, Marcucci says. Bo...
A new method of adult stem cell growth efficacious in treatment of disorders of the cornea
...d the clinical application of the adult stem cells transplant
in rabbits, which previously have had an epithelia... is a pathology that does not respond to a corneal transplant
nor to other conventional treatment. The procedure used by Dr Fernndez Hortelano involved obtainin...
Stem cell therapy rescues motor neurons in ALS model
... and their chemical secretions. "We only put the transplant
in one small area of the spinal cord and only on one side," Suzuki says. "The areas where we saw the human cells were the only areas where we saw protection of motor neurons." But while the motor neurons exposed to GDNF were protected, the Wisconsi...
Scientists move closer to bio-engineered bladders
...the potential to produce viable bladder tissue for transplant
into patients who need replacement bladders." The York research highlights the importance of basic biology research in underpinning medical advances. Professor Nigel Brown, BBSRC Director of Science and Technology, commented: "Fundamental bioscienc...
Fish eyes could hold clue to repairing damaged retinas in humans
... be possible to store the cells in a cell bank and transplant
them into the eye or to use cells from a person's own eye." Using their own cells rather than a donor's has the advantage that their immune system is less likely to reject the treatment. Although Mller glial cells are present in the human eye, i...
UF to lead research on life-threatening fungus
...n Wingard, M.D., director of UF's blood and marrow transplant
program anddeputy director of the UF Shands Cancer...ading cause of death from infection in bone marrow transplant
and leukemia patients, as well as among those who receive certain other solid organ transplants, he ...
First case of successful ovarian tissue transplantation between two, nonidentical sisters
...nd radiotherapy, has received a successful ovarian transplant
from her genetically non-identical sister. The transplant
restored her ovarian function, she started to menstruate and, after a year, doctors were able to rec...
Aggressive therapy best for certain AML patients
...aggressive therapy such as an autologous stem cell transplant
while they are in remission might significantly ex...tend their disease-free survival. An autologous transplant
uses stem cells taken from the patient's own blood. The research was led by investigators at the ...
Marijuana component opens the door for virus that causes Kaposi's sarcoma
...h lowered immune systems, such as AIDS patients or transplant
recipients, are more susceptible to developing the sarcoma as a result of infection. Their findings, reported in the August 1 issue of Cancer Research, a journal of the American Association for Cancer Research, offer cautionary evidence that those w...
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