NIH awards new $14.5 million, five-year grant to the Scripps Research Institute
...are also almost always unique, demanding a lengthy trial and error search for those exact conditions in which the protein-detergent complexes will be soluble and stable. In addition, the costs of the detergents alone can easily add up to hundreds of thousands of dollars. "The preparation of membrane pro...US researchers show cottonseed drug is cancer treatment booster
... the findings clinically tested soon and a Phase I trial is planned....Amgen investigational therapy, AMG 162, increased bone mineral density with twice yearly injection
...of the ongoing multi-center, Phase 2, dose ranging trial in healthy postmenopausal women with low BMD were ...26th Annual Meeting in Seattle. This double blind trial was designed to evaluate the safety and efficacy of AMG 162 compared with placebo with an open label...September/October 2004 Annals of Family Medicine tip sheet
...8 and 30 who participated in a randomized clinical trial testing the effectiveness of brief alcohol counseling, the authors found that counseling resulted in long-term reductions in high-risk drinking behaviors and adverse events. Comparing results of those who received counseling with those who did not, t...After flu exposure, mild exercise protects mature mice from dying
...oratory also has a large NIH-funded human clinical trial underway examining whether or not moderate exercise training can improve immunological vigor --including responses to influenza vaccine -- in older adults....Experts present new research on hot topics in aging at GSA's annual meeting in Washington, DC
...lderly) was a randomized, controlled, single-blind trial to evaluate if three cognitive training interventions (memory, reasoning, speed of processing) improved cognitive abilities and daily functioning in older, independent-living adults (n=2,802; mean age = 73.6 yrs). Participants were assessed at baseli...Award-winning INEEL probe to help safely monitor hazardous waste sites
...by its creators. "This technology wasn't born from trial and error," Jones says. "We sat down and thought through all the possible problems and things that could go wrong. Then we designed the flaws out from the start." Faced with a 1960s-era nuclear waste site that they needed to sample directly, Jones an...Delay in cutting the cord helps premature babies
...row up. She is conducting a randomized controlled trial funded by the National Institutes of Health of early versus later clamping times in 74 preterm babies. In this study, the infants will be followed until they are 7 months old when developmental testing will be done. Eventually, she hopes to track th...Study is looking at ways to help stroke survivors regain lost motor skills
...l in Chicago. Dr. Levy presented this feasibility trial data at the Congress of Neurological Surgeons Wednesday in San Francisco. The trial showed that study participants stroke survivors suffering impaired hand or arm movement who underw...Genetics play role in response to most common asthma drug
... The Beta-Adrenergic Response by Genotype (BARGE) trial is the first study of an asthma drug in patients s... the October 23-29 issue of the Lancet,* the BARGE trial provides important insight as to why albuterol may benefit some people with asthma more than others....Study at Joslin shows ease of introducing technology to kids with diabetes
... the DAILY Study The four-week pilot study trial included 40 children and adolescents with type 1 diabetes who were receiving their care at Joslin Clinic in Boston. The participants were divided into two groups: the Game Group and the Control Group. The Game Group received a blood glucose meter, PD...Gene therapy approach reverses diabetic neuropathy in animal model, Pitt study finds
... but in order to bring this approach to a clinical trial we must first carry out toxicology studies with th...ity of Michigan, will conduct a human gene therapy trial for the treatment of cancer pain that will employ an HSV vector. According to Dr. Goss, once an addi...VYTORIN (TM) superior again to Lipitor at lowering LDL (bad) cholesterol
...N.J., Oct. 28, 2004 -- Results from a new clinical trial conducted in 1,902 patients with high cholesterol showed that VYTORIN TM (ezetimibe/simvastatin) provided greater reduction in LDL ("bad") cholesterol across the dosing ranges compared to Lipitor. At the most commonly used starting doses of these t...Safety and immunogenicity data available for new pertussis booster vaccine candidate for adolescents
...Vaccine, Adsorbed (Tdap)]. The Phase III clinical trial involved over 4,000 adolescents in the United States and showed Boostrix to be comparable to a U.S.- licensed Tetanus Diphtheria (Td) vaccine with regard to safety and immunogenicity. In addition, the use of Boostrix induced anti-pertussis antibody ...OneWorld Health presents preliminary clinical trial results at ASTMH
The initial results of a Phase III clinical trial in India for a low-cost drug to cure a deadly parasitic disease will be presented by Victoria Hale, Ph.D., founder and CEO of the Institute for OneWorld Health, the first nonprofit pharmaceutical company in the U.S. The results will be made at the A...First human trial of bioartificial kidney shows promise for acute renal failure
...t in kidney function. The patients enrolled in the trial faced an average 86 percent likelihood of dying at...s says. For now, a randomized, controlled phase II trial of the RAD in acute renal failure is currently underway at six academic medical centers under invest...Loyola begins study on blood substitute in trauma patients at the scene of injury
...y Health System begins today the national clinical trial using PolyHeme®, an investigational oxygen-car...uman Research Subjects (IRB) approved the clinical trial in May. Loyola is one of 20-25 Level I trauma centers which will participate in the trial nationwid...Link between immune protein and longer survival in melanoma patients identified
... 75 percent of the patients in a phase II clinical trial of a melanoma vaccine. The vaccine was also associated with tumor regression....OneWorld Health named business leader in public health on '2004 Scientific American 50'
...eliminary positive results of a Phase III clinical trial in India for a low-cost drug to cure a deadly parasitic disease, visceral leishmaniasis (VL) during a scientific session at the 53rd annual meeting of the American Society of Tropical Medicine and Hygiene (ASTMH) in Miami, Fla. VL kills approximatel...... holders to produce anti-cancer drugs for clinical trial and the market. According to Manuel Carrondo, CEO of IBET, the importance of the projects goes well beyond the research itself. "It is critical for us in a small country to work with the top European companies and the success of these projects will h...