UK is first to administer new anti-clotting technology
...e is one of two sites participating in the Phase 1 trial and is the first site to use the anti-clotting drug and its antidote. This clinical trial will examine the drug's safety and tolerability in healthy volunteers as well as the antidote's abil...Biovest International announces that it will report new follow-up data
...follow-up data from its BiovaxID Phase II clinical trial is available on-line at www.hematology.org . The ... mortalities. Additional analysis of the Phase II trial data will be presented by Biovest at the American Society for Hematology meeting. The abstract repo...UF scientists find sugar may have a sour side
... conducting a National Institutes of Health-funded trial to determine if lowering uric acid in blacks with hypertension improves blood pressure control and are collaborating with scientists at Baylor to determine if lowering uric acid will reduce blood pressure in adolescents with hypertension. "We cannot......term Effects ofReducing Intake of Energy (CALERIE) trial at Tufts, the authors studied32 healthy overweight adults on a reduced-calorie diet for six months.Half of the subjects were randomly assigned to a low glycemic load diet,and the other half followed a diet with a high glycemic load. "A food's glycemi...Herceptin plus chemotherapy improves disease-free survival in early breast cancer
...p (BCIRG), this study is the fourth large clinical trial to show that Herceptin plus chemotherapy significantly reduces risk of disease recurrence in early breast cancer. Results were presented Thursday at the San Antonio Breast Cancer Symposium by Dr. Dennis Slamon, co-chairman of BCIRG, director of Clini...Data in New England Journal of Medicine show benefits of REMICADE in ulcerative colitis patients
...litis (UC). At week 8, in both the 54-week ACT 1 trial and the 30-week ACT 2 trial, statistically signifi...ucosal healing from week 8 through the end of each trial (week 54 in ACT 1 and week 30 in ACT 2). A major advance in the treatment of UC, REMICADE is the f...AutovaxID-C introduced by Accentia Biopharmaceuticals
... and it is currently in a pivotal Phase 3 clinical trial started by the National Cancer Institute. In addi...axID TM , is currently in Phase 3 pivotal clinical trial at over 20 major centers in the US being conducted under a Cooperative Research and Development Agre...AutovaxID-C introduced by Biovest International
...axIDTM, is currently in a Phase 3 pivotal clinical trial at over 20 major centers in the US being conducted under a Cooperative Research and Development Agreement (CRADA) with the National Cancer Institute. For further information, please visit Biovest's website: www.biovest.com...Eisai announces Phase II data on E7389, a potential new therapy for the treatment of breast cancer
...actory breast cancer. The primary endpoint of this trial was response rate, measured using the RECIST (Response Evaluation Criteria In Solid Tumors) criteria a group of standards used to measure responses to treatment in solid tumors. Of the 65 evaluable patients, 10 partial responses were confirmed at th...Study shows combination of immune substances to be safe
...ues are conducting a multicenter phase II clinical trial of the two drugs in people with melanoma. Phase-II trials are the first step in determining the effectiveness of new therapy against a specific disease. "We believe that use of the two drugs together will give us more bang for the buck," says first...Pramipexole delivered sustained efficacy in clinical trial of patients with Restless Legs Syndrome
... These trials are part of a comprehensive clinical trial program, involving more than 1,000 patients, to assess the therapeutic potential of pramipexole in the treatment of RLS. Boehringer Ingelheim, the discoverer of the molecule, has also recently submitted applications for international regulatory appr...New data suggest pramipexole relieves symptoms of Restless Legs Syndrome (RLS) and is well-tolerated
...ovement (CGI I) scale. Results after six weeks of trial therapy showed that: Improvement in the IRLS was... other trials are part of a comprehensive clinical trial program, involving more than 1,000 patients, to assess the therapeutic potential of pramipexole in t...REVLIMID improves overall survival and delays disease progression in multiple myeloma patients
...ical data from the pivotal International Phase III trial (MM-010), demonstrated that the combination of REV...cal data from the pivotal North American Phase III trial (MM-009), reported that the combination of REVLIMID plus dexamethasone led to a statistically signif...New Phase 3 data show potential benefits of Aranesp dosed every three weeks for CIA
...domized, double-blind, placebo-controlled, Phase 3 trial of Aranesp (darbepoetin alfa) administered every t...domized, double-blind, placebo-controlled, Phase 3 trial assessed the efficacy and safety of a fixed dose of 300 mcg of Aranesp administered every three week...Hearing loss from chemotherapy underestimated
... study team is developing protocols for a clinical trial of a second potential chemo-protectant called N-acetylcysteine, or NAC. The drug, typically used to treat people with Tylenol poisoning, prevented platinum-induced ototoxicity in rats in a study published in mid-2004. NAC may prevent hearing loss by ...New study finds common herbal supplement helps to reduce cocaine cravings
...lp to control their cravings." A larger clinical trial that will follow 282 cocaine-dependent individuals has just begun in order to further understand and corroborate how NAC works in the brain to reduce cocaine craving. Dr. Kalivas stresses that while the initial findings are very promising, the wides...South African geraniums effective in treatment of adults with acute bronchitis
...ADELPHIA, PA, December 13, 2005 A recent clinical trial in Europe showed that EPs 7630, a remedy made from...the EPs 7630 group reported complete recovery. The trial was conducted by AG Chuchalin, MD, of the Russian Research Institute of Pulmonology in Moscow, Russi...Researchers explain why badger culling fails to control cattle TB
... organisation. The study was based on 13 of the 30 trial areas enrolled in the Randomised Badger Culling Trial, including Devon, Cornwall, Herefordshire, Staffordshire, Derbyshire and Somerset. By placing bait (peanuts mixed with treacle) containing colour markers (small indigestible plastic beads) at main...Gene variation affects tamoxifen's benefit for breast cancer
...y research group conducting a prospective clinical trial to confirm whether genetic testing can be used to ... estrogen in breast tissue. The findings from this trial were derived from a large North Central Cancer Treatment Group study in which women were treated wit...Studies show benefits of newborn screening for 'bubble boy disease'
...should be addressed in a multi-center, prospective trial to determine accurately the incidence, specificity, sensitivity and cost of SCID newborn screening. The incidence of SCID is unknown but may be more common than published estimates because infants frequently die of infection before diagnosis. If an i...