Tag: "trial" at biology news
Other highlights in the November 17 JNCI
... analyses of data from a large randomized clinical trial
suggested that selenium intake reduces the risk of... randomized trial. In 1986, a randomized phase III trial
began in which 237 patients with nonmetastatic stage III or IV head and neck squamous cell carcinoma...
University of South Florida designated Center of Excellence by Huntington's Disease Society
...n ongoing multicenter, placebo-controlled clinical trial
investigating whether the drug tetrabenazine is beneficial and at what dosage might it improve chorea -- the excessive, involuntary movements affecting most people with Huntington's Disease. Research on Huntington's Disease may advance the...
Novel biotoxin being studied for use in opioid withdrawal
...004 investigators involved in a Phase IIa clinical trial
of the novel biotoxin Tetrodotoxin (TTX) for the t...-blind, randomized, cross-over, placebo-controlled trial
will evaluate the efficacy and safety of Tetrodin for treatment withdrawal symptoms in 20 opiate-dep...
Good news about vitamin E
...om the Heart Outcomes Prevention Evaluation (HOPE) trial
of 2000, designed to study the effect of antioxidant therapy such as vitamin E on cardiovascular risk. The results of that study showed no benefit from vitamin E therapy on cardiovascular risk. However, Dr. Levy notes, the study did not segregate pa...
Columbia researchers identify drug as therapeutic candidate for spinal muscular atrophy
...city testing of related drug molecules. A clinical trial
for its effectiveness in treating SMA could follow. It should be noted that the researchers found that ibuprofen and other nonsteroidal anti-inflammatory drugs had no effect on increasing the production of the protein lacking in individuals with SMA....
Stronger therapy better for AML with normal genetics
...C-James). It is part of a larger CALGB cytogenetic trial
chaired by Clara D. Bloomfield, professor of internal medicine and the William G. Pace III Professor in Cancer Research, OSU Cancer Scholar and senior adviser to the OSU cancer program. Unexpectedly, the current study also found that patients who...
UT Southwestern initiating trials in humans for ricin vaccine
...rn Institutional Review Board have agreed that the trial
can go forward in humans. "This is a safety and i...ng antibodies, Dr. Vitetta said. The pilot phase I trial
to be carried out by Dr. Robert Munford, professor of internal medicine and microbiology is design...
New drug sidesteps Gleevec resistance in human trials
...id Sawyers. "In fact, the results of this clinical trial
match very closely with what we would have predicted the outcome to be based on our earlier studies of this drug in mice." The 36 patients treated by Sawyers and his colleagues were given BMS-354825 in doses ranging from 15 to 180 mg per day taken or...
Stanford study links obesity to hormonal changes from lack of sleep
...d treat obesity. Mignot is working on setting up a trial
to study this approach. ...
New breast cancer study shows hormonal therapy not enough
... "Long-term follow-up of this large North American trial
confirms that chemotherapy benefits postmenopausal women with hormone-dependent breast cancer," said Albain. "We discovered that women with very high levels of estrogen receptor in their tumors can probably avoid chemotherapy, but those with lower o...
Encouraging results from validation study of trial of personalized treatment in breast cancer
...gene signature to be used in the first large-scale trial
to study the role of such tumor signatures in brea...encouraging and gives the green light to start the trial
proper, Dr. Martine Piccart, head of the medical oncology department at the Institut Jules Bordet in...
False positive screening for cancer found to be frequent and costly
...87 individuals participating in a cancer screening trial
who received a battery of tests for prostate, ovar... National Cancer Institute and is part of a larger trial
of the effectiveness of screening for prostate, lung, colorectal and ovarian cancers. "The results...
National study finds second cesarean section safer than normal delivery
... of adverse perinatal outcomes is increased with a trial
of labor after a prior cesarean delivery but also ...greater among the infants of women who underwent a trial
of labor" than among the infants of women who elected a second cesarean. "The rate was eight per 10...
Science's Breakthrough of the Year: Salty, acidic soup could have supported life on Mars
...initiatives this year, including a malaria vaccine trial
and efforts to provide anti-HIV drugs. Genes in a Drop of Water: In 2004, researchers hit on a new way to identify life forms too small and remote to see with the naked eye. They collected water from environments as different as the Sargasso Sea an...
Combined stem cell-gene therapy approach seen as potential treatment for cystic fibrosis
...d are hopeful that we can perform a small clinical trial
within the next two to three years," noted senior author Jay K. Kolls, M.D., professor of pediatrics, immunology and molecular genetics and biochemistry at the University of Pittsburgh School of Medicine and chief, Division of Pediatric Pulmonology a...
Timing is everything for optimum combined cancer therapy
...e five months seen in the recent landmark clinical trial
of combination therapy."...
Essential oils could help to stamp out MRSA
...and other 'super bugs', but we need to carry out a trial
and to do that we need a small amount of funding around 30,000. "We are having problems finding this funding because essential oils cannot be patented as they are naturally occurring, so few drug companies are interested in our work as they do not...
NSBRI news: Bone-quality assessment tool for space and Earth
...precision, and the second phase; eventual clinical trial
and commercial buy-in. From shuttle flights and missions aboard the ISS to future interplanetary travel, the SCAD device could provide immediate emergency diagnosis for injuries or conditions that might otherwise halt a mission. "Aside from use infl...
US Oncology, Inc. plays role in newly approved ABRAXANE for metastatic breast cancer
...t cancer. US Oncology conducted a phase 2 clinical trial
of ABRAXANE in patients with metastatic breast can...principal investigator of the US Oncology clinical trial
of ABRAXANE. To date, the formulation of insoluble tumor-fighting agents, such as paclitaxel, has r...
FDA approves ABRAXANE(TM) for metastatic breast cancer
... solvent-based Taxol in a prospectively randomized trial
of 460 patients with metastatic breast cancer. Be...metastatic breast cancer," said principal clinical trial
investigator William J. Gradishar, M.D., Associate Professor of Medicine, Division of Hematology and...
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