Tag: "trial" at biology news
From gene discovery to preventing eye disease in retinitis pigmentosa
...hen counseled about this vulnerability. A clinical trial
is definitely indicated." The research from the Penn-Cornell investigators ushers in a new era of eye-disease prevention by considering the interaction of genetics and environment in this case exposure to light on an individual basis. The investiga...
Fish oil holds promise in Alzheimer's fight
...profile--essentially no side effects--and clinical trial
evidence supports giving DHA supplements to people at risk for cardiovascular disease." The new study involved older mice genetically altered to develop Alzheimer's disease. The researchers fed one group of the mice DHA-fortified chow. The control ...
Salk polio vaccine celebrates 50th anniversary
...nfantile Paralysis) conducted the largest clinical trial
in U.S. history, testing the vaccine developed by Jonas Salk, M.D, on more than 1.8 million schoolchildren. Thousands of health care workers and other volunteers across the country participated to make it possible. No wonder, then, that millions of ...
Gene variations explain drug dose required to control seizures
...ondon. Patients often undergo a lengthy process of trial
and error to find the dose of anti-epilepsy drugs ... be applied to medicine in such a way as to reduce trial
and error and improve quality of life for patients," he added. Epilepsy and seizures affect 2.5 mill...
Aspirin is safer than warfarin and just as effective for treating blocked arteries in the brain
...ow, results of a double-blind, randomized clinical trial
show for the first time that aspirin works as well... of the National Institutes of Health (NIH). "This trial
is good news. A simple low-cost drug works just as well as one that requires complicated and expens...
NASH clinical research network launches new trial for treatment of liver disease
...he NASH Clinical Research Network and the clinical trial
are funded by the National Institute of Diabetes a...tients with Nonalcoholic Steatohepatitis" (PIVENS) trial
is currently recruiting non-diabetic patients and will enroll 240 adults over 2 years into one of th...
Researchers test new therapy for advanced melanoma
...st melanoma tumors. "This is a milestone clinical trial
because it is the first time that electroporation ...ller and his colleagues preceded the initial human trial
begun earlier this year at Moffitt. The collaboration of USF and Moffitt in this trial
is a good exa...
Lung cancer vaccine trial continues at UK's Markey Cancer Center
...lead to recurrences after cancer treatment. "This trial
is important in the fight against lung cancer because additional medical therapies are not generally recommended until recurrences are seen," said Hirschowitz. "We are using the window between definitive medical or surgical therapy and lung cancer r...
Other highlights in the April 6 JNCI
...n Hong Kong, and colleagues conducted a randomized trial
in which 350 patients with locoregionally advanced...non, France, and colleagues conducted a randomized trial
in which 181 patients with advanced NSCLC, who responded to induction treatment, were randomly assig...
Molecular testing impact: Heart transplant patients benefit from new technology, easier monitoring
... on LARGO, an international, multi-center clinical trial
that studies the ability of AlloMap to improve clinical management of lung transplant recipients. He will also discuss his work on molecular evaluations of donor lungs....
Scientists making advances receive international awards
...conceiving, designing, and organizing the clinical trial
arm of the Women's Health Initiative. The award is intended to distinguish outstanding achievements in the fields of epidemiology, biomarkers, and prevention. Prentice will present his lecture on "Opportunities and challenges in chronic disease prev...
OneWorld Health receives multimillion dollar grant for next steps in control of deadly disease
...t-approval Phase IV study, and complete a clinical trial
of shorter duration of administration to optimize ...on last November of the largest Phase III clinical trial
ever conducted for VL. VL, also known as kala azar ("black fever"), is a fatal disease transmitted...
Protective effect of calcium in reducing colon cancer polyps lasts for years
...at patients in the treatment group of a randomized trial
of calcium supplements had a 36 percent reduction ...tive against development of colorectal polyps. The trial
that proved that association, the Calcium Polyp Prevention Study, randomized 930 patients who had a ...
Compound from Chinese medicine shows promise in head and neck cancer, U-M study finds
...althy tissue. Researchers hope to begin a clinical trial
within a year, testing whether (-)-gossypol can be used along with chemotherapy to create a better response and avoid surgery. More than 29,000 people will be diagnosed in 2005 with head and neck cancers, which include cancer of the tongue, mouth, t...
Next-era targeted therapy overcoming Gleevec's shortcomings
...rate in over 100 patients enrolled in the clinical trial
to date continues to improve, as doses are rapidly increased. The first patients began treatment at 50 milligrams, but now all are taking 400 milligrams twice a day "and we have certainly not reached a dose-limiting toxicity," Giles say. "The drug is...
Scientists infuse rat spinal cords with brain-derived human stem cells
...d where motor neurons are located. After months of trial
and error, Klein finally ascertained through stain...ys Svendsen. If so, he aims to plan a human safety trial
with a small group of patients. Ordinarily, the researchers would first test the work in primates, b...
Readers of genome decipher signatures of cancer patient outcomes
...aid. "Many of those patients can consider clinical trial
options that they may otherwise have overlooked or not feel justified. "If you identify the ones who are at a high likelihood of therapy failure, and therefore are candidates for more aggressive and often individually designed therapies, required tre...
Fox Chase Cancer Center researchers identify subset of ovarian cancer patients responsive to Iressa
...ers examined archived tumor tissue from a phase II trial
designed to assess the activity and tolerability o...bjective response to gefitinib during the 23-month trial
had a mutation in the tyrosine kinase portion of the EGFR. Conversely, no mutations were observed i...
Fox Chase Cancer Center researchers: Selenium will have critical role in prostate cancer treatment
...n of the large National Cancer Institute sponsored trial
- SELECT (Selenium and Vitamin E Chemoprevention Trial). The epidemiologic studies within SELECT will be based on 32,000 men." With this in mind, Kolenko and colleagues went a step further and studied the effect of methylseleninic acid (MSA), a nove...
Green tea shown to prevent prostate cancer
...tuzzi explained. "We wanted to conduct a clinical trial
to find out whether catechins could prevent cancer in men. The answer clearly is yes." Earlier research demonstrated primarily that green tea catechins were safe for use in humans. Bettuzzi and his colleagues had found that EGCG targets prostate ca...
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