Sedentary overweight people get insulin boost from short term exercise; CVD risks trend down
... weight loss was 0.7 kg in NEG and .03 kg in ZERO; triglycerides declined 16% in NEG, 5.3% in ZERO; total cholesterol declined modestly for NEG and was steady in ZERO; HDL (high-density lipoprotein) was unchanged in NEG, but actually fell in the ZERO group; there was an 18.5% decrease in CRP (C-reactive protein) a...Gene linked to greater risk of heart disease in type 2 diabetes
...k emerged -- the highest levels of fatty acids and triglycerides occurred in people with a specific variant combination. Using this new knowledge as a basis for a second study, they studied 518 people in both the United States and Italy. All had type 2 diabetes. In addition, nearly half of these subjects also had ...VYTORIN (TM) superior again to Lipitor at lowering LDL (bad) cholesterol
...levated total cholesterol, LDL cholesterol, Apo B, triglycerides and non-HDL cholesterol and to increase HDL cholesterol in patients with primary (heterozygous familial and non-familial) hypercholesterolemia or mixed hyperlipidemia. VYTORIN also is indicated for the reduction of elevated total cholesterol and LDL...Fat buildup found in hearts of obese or diabetic heart failure patients
... failing hearts (30 percent) showed high levels of triglycerides a fat storage and transport molecule. Levels of triglycerides in failing hearts were four times the level in obese or diabetic patients as they were in non-failin...Young adults who maintain their weight have lower risk factor levels for heart disease
...d their weight had only a 1 mg/dL rise per year in triglycerides (harmful fat in the blood) compared to a 4 mg/dL p...15 years, that translates into a total increase in triglycerides of 60 versus 15 mg/dL in those who gained compared with those who maintained stable weight. Normal w...Study in Royal Society journal on managing GM crops for environmental benefit
...h fatty acid circulation is supplemented by plasma triglycerides a pathway previously hypothesized to apply only to small migrants. Contact: Dr Meta Landys, Department of Biology, University of Oslo, PO Box 1050, OSLO, N-0316, Norway Sperm influences female hibernation success, survival and fitness in the bumble...Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
...ds causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and cert..., which is responsible for the body's synthesis of triglycerides and cholesterol, but the molecular chain of events from eating fats to the buildup of cholesterol an...Mouse with designer liver has enhanced glucose tolerance and improved insulin response
... lower levels of serum insulin. The mice retained triglycerides in the liver with a commensurate decrease of circulating triglycerides in the bloodstream. Insulin response to glucose load was diminished in LGKO mice, thus glucose tole...FGF-21 finds itself as a new therapy for type 2 diabetes
...tion of FGF-21 decreased plasma glucose levels and triglycerides to near normal levels in multiple mouse models of type 2 diabetes. FGF-21, when overexpressed, protected animals from diet-induced obesity. These results define a functional role for FGF-21 in vivo and provide evidence that FGF-21 can lower glucose...JCI table of contents June 1, 2005
...tion of FGF-21 decreased plasma glucose levels and triglycerides to near normal levels in multiple mouse models of type 2 diabetes. FGF-21, when overexpressed, protected animals from diet-induced obesity. These results define a functional role for FGF-21 in vivo and provide evidence that FGF-21 can lower glucose...New study demonstrated add-on effects of ACTOS (pioglitazone HCl)
...er triglycerides. Low HDL cholesterol and elevated triglycerides represent cardiovascular risk factors for patients... normal levels of LDL, yet lower HDL and increased triglycerides that single lipid therapy alone may not address," noted Dr. Spanheimer. Study Background and Des...Study reveals trigger for insulin resistance in liver, potential drug targets
... function, elevated lipids such as cholesterol and triglycerides in the bloodstream, and progression to liver cirrhosis, he said. Characterized by scarring, cirrhosis of the liver is the twelfth leading cause of death by disease, according to the National Institute of Diabetes and Digestive and Kidney Diseases (NI...Researchers outline possible drug targets for treating metabolic syndrome
...cose intolerance; blood fat disorders, mainly high triglycerides and low high-density lipoproteins, or "good" cholesterol; and abnormalities in blood clotting. Any one of these disorders by itself is a risk for certain diseases, but in combination they can dramatically boost one's chances for developing life-threa...Soy protein reduces effects of diabetes on liver
...ption of soy protein prevented the accumulation of triglycerides and cholesterol in the liver despite the developme...genes involved in the synthesis of fatty acids and triglycerides in the liver," explained Dr. Torres. "These changes were due to a reduction in the transcription fac...Baby's genes affect mom's cholesterol levels
... that are known to influence the concentrations of triglycerides and cholesterol in the general population. They fo...ple, a genetic variation that raises the levels of triglycerides and cholesterol when expressed in mothers may lower these levels when it is expressed simultaneously...UF scientists find sugar may have a sour side
... were able to significantly reduce the rise in the triglycerides in the blood, the insulin resistance was less and the blood pressure fell." UF researchers are now studying the uric acid pathway in cell cultures in the laboratory, in animals and in people, and are also eyeing it as a possible factor in the develop...Three-week diet/exercise study shows 50 percent reversal in metabolic syndrome, Type 2 diabetes
...ce, and blood fat disorders such as high levels of triglycerides (fat in the blood) or low levels of HDL (high density lipoprotein, or "good" cholesterol). Thirteen of the participants had Type 2 diabetes. There was also some overlap between the two groups and some participants who had neither metabolic syndrome n...Fat overload kills mammalian cells key culprit identified
...aggressive with respect to lowering lipids such as triglycerides and fatty acids." With the discovery of EF1A-1's role, this study is the first to identify a critical step in the pathway that leads from high cellular fat to cell death, according to Schaffer. EF1A-1 is an extremely abundant protein with several di...JCI table of contents, February 16, 2006
...ase (NAFLD), caused by the build up of fats called triglycerides in the liver. Severe cases of NAFLD are associated with steatohepatitis, in which the liver progresses to end-stage liver disease requiring transplant. Interestingly, this disorder is also associated with insulin resistance, and therefore contributes...Researcher tackles complexities of obesity, diabetes and their age-related complications
...alth problems such as high blood pressure and high triglycerides and to prevent or delay the progression of insulin resistance toward diabetes. Monkeys whose food intake was maintained in amounts to assure a constant healthy body weight were not only healthier; on the average they lived longer than their counterpa...