Tag: "tumor" at biology news
Scratch no more: Gene for itch sensation discovered
... thing they've found is that GRPR is implicated in tumor
growth. As a result of research like this, a lot of substances have been made that block the activity of GRPR. So now researchers can study the effect of these agents on the itch sensation and possibly move that research to clinical applications fair...
Other highlights in the July 24 JNCI
... not cause breast cancer. Instead it could promote tumor
growth while its withdrawal may slow or stop it. They add that using individual-basedin addition to population-baseddata would give researchers a better picture of relationship between hormone therapy use and breast cancer. These additional analys...
CTRC enrolls first patients in novel phase II study for sarcoma -- living virus destroys cancer cell
...gent study with the primary objective of measuring tumor
responses and the duration of those responses, and of describing any evidence of anti-tumor activity. REOLYSIN will be given intravenously to patients for five consecutive days. Patients may receive additional five-day cycles of therapy every four w...
JCI table of contents: July 19, 2007
... ONCOLOGY A little more PDGF-BB, a little less tumor
growth The formation of new blood vessels (angi...(platelet-derived growth factor BB) contributes to tumor
growth and spread by enhancing the envelopment of newly formed vessels with stabilizing pericytes, a...
MIT IDs link between brain tumor proteins
...astoma multiforme (GBM), the most aggressive brain tumor
in adults, strikes about 15,000 people in the Unit...red a connection between two proteins found in the tumor
cells, and they have demonstrated that attacking both of those proteins kills tumor
cells much more ...
Immune system 'escape hatch' gives cancer cells traction
...aved. Using chemical tests in which individual tumor
cells can be tagged with a fluorescent dye that al...ting immune cell binding to and marking of foreign tumor
cells. Peroxynitrate activity is the escape hatch, and now that we have identified it, we can try ...
Scientists take next step in understanding potential target for ovarian cancer treatment
...ound altered forms of the protein in 42 percent of tumor
tissue samples taken from women with ovarian cancer. No similar alterations were found in normal human tissues, suggesting that the km23 alterations may be a possible diagnostic indicator for development of ovarian cancer and that the km23 protein...
Tumor painting revolutionizes fight against cancer
SEATTLE: July 15, 2007 -- A tumor
paint developed by researchers at Seattle Children...cer Research Center will help surgeons see where a tumor
begins and ends more precisely by illuminating the cancerous cells. The study, published in the July...
...ter and colleagues were able to successfully fight tumor
formation in a preclinical model by suppressing IL6 activity. While further research is needed to determine the effectiveness of IL6 targeted cancer therapies, these initial results are encouraging. "Targeting secreted proteins that Ras activates has...
JCI table of contents: July 12, 2007
... a lack of ER-alpha detection, and more aggressive tumor
growth. The authors conclude that their study provides a rationale for the use of Src inhibitors in breast cancer therapy. TITLE: Src promotes estrogen-dependent estrogen receptor alpha proteolysis in human breast cancer AUTHOR CONTACT: Joyce M....
Antibody retards growth and induces death in liver cancer cells
...ibody, they demonstrated significant reductions in tumor
cell proliferation and survival in human and mouse...st PDGFR. It resulted in a significant decrease in tumor
cell proliferation and a marked increase in tumor
cell death. In fact, all tumor
cell lines experien...
Biodesign Institute leads innovative project to prevent cancer
...tively represent any foreign protein that a breast tumor
would produce, the immune system would arm itself against breast cancer, said Lake. And, if the platform technology proves successful, it could be applied to other cancers. The Biodesign Institute duo will lead a highly interdisciplinary team of s...
Other highlights from the July 10 JNCI
...e difficult because it requires a way to image the tumor
prior to treatment. Natalya Rapoport, Ph.D., D....d, the nanobubbles were more effective at blocking tumor
growth than other nanoparticle delivery methods. Microbubble formulations have been developed fo...
Scientists follow familiar TRAIL to new cancer therapy
...d for enhancing the potency and effectiveness of a tumor
necrosis factor (TNF) death receptor ligand against a variety of human cancers. Potency and lack of toxicity to normal tissues make activation of TNF-a-related apoptosis-inducing ligand (TRAIL) death receptor signaling an attractive and exciting t...
U-M, Israeli scientists report major advance in search for genes associated with colon cancer
...azi Jew, Sephardic Jew or Arab/non-Jew. Samples of tumor
tissue from many cancer patients were also tested. The genetic link between the marker and colon cancer was especially strong among patients diagnosed with colon cancer at a young age, under 50 years. Stephen Gruber, M.D., Ph.D., the co-leader of ...
New imaging method clarifies nutrient cycle
...tissues react upon implantation of a metastasizing tumor
cell, and what does the tumor
cell synthesize in order to make implantation possible" ...
Researchers identify genetic mutation that may alter tumor cell proliferation
...cancers. The altered form of AKT1 appears to cause tumor
cell proliferation and may play a role in making c...fy the AKT1 mutation, the researchers analyzed 150 tumor
samples from patients with either breast, colorectal or ovarian cancer (50 samples from each tumor
Fat kills cancer
...ne therapy approach is a novel way to attack small tumor
metastases that evade current detection techniques.... Researchers believe mesenchymal stem cells see a tumor
as a damaged organ and migrate to it, and so might be utilized as a vehicle for treatment that can f...
Study examines cause of hearing loss for patients with certain genetic disease
... occur suddenly in a manner that is not related to tumor
size, early surgical intervention may be warranted. While this study does not address the effectiveness of surgical resection, several small operative series indicate that complete resection of ELSTs can be curative, can alleviate vestibular symptoma...
From clinical cancer research: rethinking therapeutic cancer vaccine trials
...f immune response that, in many cases may keep the tumor
in check and enhance the effectiveness of subseque... to rile the patients immune system into attacking tumor
cells. In their review Schlom and his colleagues looked at two cell-based vaccines, Sipuleucel-T (...
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