Tag: "tumor" at biology news
InfoSNM highlights advances in computer, information sciences for molecular imaging
... and image analysis using hand-held technology; a tumor
metrics measurement and tracking system; using simulation to research ideas in emission tomography; dementia evaluation using automated software-based age/sex-matched normal database comparison; 4-D phantoms for medical imaging simulation of mice...
Enhanced MR-guided focused ultrasound guidelines demonstrate improved efficacy and durability
...nes, we are able to successfully treat more of the tumor
and virtually eliminate the need for future hysterectomies."Additional data presented at ACOG this week by David Lee, Ph.D., Senior Director, Health Economics and Outcomes Research, GE Healthcare, showed that clinically significant uterine fibroids a...
Cancer cells 'reprogram' energy needs to grow and spread, study suggests
...at that it can be used to identify small groups of tumor
cells that have spread throughout the body. Although changes in mitochondria have been described in many cancers, the Hopkins study shows for the first time how a cancer-causing mutation can block their production. "There must be a strong adva...
Pancreatic cancer markers identified, may predict survival
... this study, Bloomston and his colleagues examined tumor
samples from 65 patients with adenocarcinoma of th...the disease. They extracted miRNA from isolated tumor
cells and from adjacent noncancerous pancreatic tissue. In addition, they isolated miRNA from the pa...
Catching cancer's spread by watching hemoglobin
...d the size and density of blood vessels around the tumor
can provide a lot of information about the progression of a tumor
and its response to anti-cancer drugs. In the technique, two lasers at different wavelengths (colo...
Fat tissue-derived hormone leptin increases e-cadherin expression, obesity-breast cancer link noted
...ercellular adhesion molecule generally viewed as a tumor
suppressor. The researchers grafted human breast c...ombined exposure to leptin and estradiol increased tumor
size, sometimes doubling it, and these changes correlated with an increase in E-cadherin. Dr. Ando...
Reversing cancer cells to normal cells
...s back to normal-like skin cells - by exposing the tumor
cells to the embryonic microenvironment of human e...f embryonic and cancer signaling pathways: role in tumor
cell plasticity." Plasticity refers to the ability of the tumor
cell, like the embryonic cell, to ex...
Breast cancer milieu -- Progression, tamoxifen sensitivity, and DNA reversion
... Carolin KA, Tait L. Direct involvement of breast tumor
fibroblasts in the modulation of tamoxifen sensitivity. Am J Pathol 2007 170:15461560. EPIGENETIC REVERSION OF BREAST CANCER DNA Using breast cancer cells, researchers have demonstrated that cancer phenotype can be reversibly altered by mani...
MicroRNAs can be tumor suppressors
...oRNAs, a form of genetic material, can function as tumor
suppressors in laboratory studies. In the May 1... let-7, and that the let-7 microRNA functions as a tumor
suppressor to prevent cancer formation in healthy cells. ...
Antioxidant found in many foods and red wine is potent and selective killer of leukemia cells
...t paradoxically induces an oxidative stress in the tumor
cells. It is possible that this differential effec...-3-R may account for its selective toxicity in the tumor
cells. According to Dr. Yin, these results indicate that C-3-R has the promising potential to be...
Gene analysis might explain ethnic differences in sensitivity to chemotherapy in lung cancer
...ntaneous mutations in the gene, or by an effect in tumor
cells that increases the number of copies of genes coding for EGFR. In the current study, the researchers compared the genes of 250 healthy people of various ethnicities with 556 samples of benign and cancerous lung tumors. They found that the thre...
Discoveries thrust cancer-initiating stem cells into a larger role in cancer biology and treatment
...portant in developing therapeutics that target the tumor
stem cell pool. These genes might also become targ...pulation of highly tumorigenic primary human colon tumor
cells, according to researchers from Biogen Idec. "Such stem cells could be responsible for the p...
Popular herbal supplement hinders the growth of pancreatic cancer cells
...of triphala for five days a week and then compared tumor
size and levels of apoptotic proteins in the tumor...ssociated with apoptosis and significantly smaller tumor
sizes when compared to the control group. Triphala-treated tumors were half the size of tumors in un...
Nutrients in certain vegetables may provide cancer-fighting benefit
... PEITC daily for 31 days had significantly reduced tumor
size when compared to a control group of mice. Now...ew blood vessels that pass oxygen and nutrients to tumor
cells. "Angiogenesis is a major issue in cancer metastases," said Dr. Singh. "Our results provide...
Cetuximab and irinotecan combination increases survival in metastatic colorectal cancer
...ved without their cancers progressing further. The tumor
response rate in this group was also significantly...provement in progression-free survival, as well as tumor
shrinkage, is worthwhile. These data confirm that, despite a moderate increase in side effects, cetu...
Cetuximab increases survival in advanced colorectal cancer patients, study shows
...iving cetuximab in the CO.17 study had significant tumor
shrinkage, many more had the cancer growth arrested, delaying progress of the disease and resulting in patients living longer." "These promising results," Jonker said, "will lead to further National Cancer Institute of Canada trials in which cetu...
Massey researchers induce cell death in leukemia
...ns between HDAC inhibitors and bortezomib in other tumor
cell types, particularly hematologic malignancies -- is certainly of interest and warrants further investigation as a potential therapeutic strategy in CLL." ...
New imaging method shows whether treatment for advanced prostate cancer is working
...s. "Currently, we have no way of detecting bone tumor
response to therapy, even with all of the imaging ...ges in diffusion over the course of treatment. The tumor
cells slow the movement of water, so as those cells die, water diffusion increases. Researchers st...
Health disparities -- Genetics, society and race play an important role in access to healthcare
...nd the physical and genetic characteristics of the tumor
itself," Gooden said. Differential Gene Expre...se "there are some shared genes," referring to the tumor
suppressor gene BRCA1, which when damaged can increase a woman's risk of both breast and ovarian can...
MicroRNAs as tumor suppressors
... Dutta (UVA) reveal that microRNAs can function as tumor
suppressors in vitro. "Overexpression of HMGA2 ... let-7, and that the let-7 microRNA functions as a tumor
suppressor to prevent cancer formation in healthy cells....
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