Omega-3 fatty acids affect risk of depression, inflammation
... in the study and tested for interleukin-6 (IL-6), tumor necrosis factor -alpha (TNF-alpha ) and the receptor molecule for IL-6. Participants also completed a survey questionnaire that gauged their level of depression. The analysis showed that participants who had much more omega-6 -- compared to omega-3...Nanoparticles for delivery of prostate cancer treatment
...e that activates an immune response to destroy the tumor blood vessels and associated tumors. Garen prev...said Garen. "We prefer to deliver the Icon gene to tumor cells, so that they cause their own destruction." The Yale scientists previously used a virus to d...Immune response to cancer stem cells may dictate cancer's course
...rgeting the cancer stem cells rather than the bulk tumor cells in myeloma something that gives researchers...tem. So they've concentrated on trying to identify tumor antigens and induce the immune system to attack them. The new research, however, also implies that r...Lack of a protein in lung tumors may increase risk of death
...d in a chromosome region that is often lost in the tumor cells of many lung-cancer patients. The researc...ted that patients with little or no Olig1 in their tumor cells had about a 15 percent decrease in survival. The researchers are now trying to learn the ro...Targeting tumors the natural way
... cancer cells while sparing healthy ones. The new tumor targeting strategy, presented today (March 25) at ...by Carlson. "It's just not usually directed toward tumor cells." In a series of cell-based experiments, the researchers' system recognized and killed only t...Blood's clotting cells harbor 'ticking time bombs,' finding may help extend blood supply
... targeting Bcl-xL and related prosurvival genes in tumor cells. Bcl-xLs newfound role reveals that the new cancer drugs will likely lead to a decline in platelet numbers. However, the researchers added, the side effect is likely to be self-limiting as normal bone marrow has the capacity to compensate by ...Scientists identify a gene that may suppress colorectal cancer
...e array of environmental and genetic influences on tumor initiation, development, and progression in the hu...r genes, which may function to enhance or suppress tumor initiation, growth and/or progression. Atp5a1 is a modifier gene, and it is located on the same c...Small molecule derived from Rb2/p130 could act as cancer therapeutic
...e Rb2/p130 has demonstrated the ability to inhibit tumor growth in vivo and could be developed into an anti...inhibition of cdk2 activity, cell cycle arrest and tumor growth reduction in vivo," in the March 22 issue of the journal Oncogene ( http://www.nature.com/onc...Notorious cancer gene may work by destroying messenger
...ests how a notorious cancer gene may contribute to tumor growth. The insight emerged from a long-running...to this day, we still don't know its exact role in tumor development, says principal investigator Daniel R. Schoenberg, professor of molecular and cellular b...Steroid hormones regulate the body clock
...Biology. To guarantee normal growth and to avoid tumor formation, the timing of cell division must be under strict control. Interestingly, the daily changes in cortisol levels observed in normal zebrafish are not required to achieve this control; treating the cortisol-deficient strains with constant leve...Soy found protective against localized prostate cancer
...ced and localized prostate cancer may be different tumor subtypes, which may react differently to isoflavones. "The present findings provide no clear understanding of when or how localized cancer will develop to aggressive cancer, and of the related effect of isoflavones," said the study's first author, ...JCI table of contents: March 15, 2007
...ITOR'S PICK: Therapeutic unshackles p53 and causes tumor regression Infection with Kaposi's sarcoma virus...s. As treatment with Nutlin-3a induced substantial tumor regression in mice with established human PEL, reactivation of p53 using Nutlin-3a might provide a v...One Wwox isn't enough (to protect against cancer)
... in humans, but it is the most common form of bone tumor and the second highest cause of cancer-related dea...nitially set out to prove that Wwox is a bona fide tumor suppressor gene. The gene is missing or altered in 85 percent of lung cancers, 65 percent of breast ...Researchers use poliovirus to destroy neuroblastoma tumors in mice
...eatment effectively protected the mice against new tumor growth, a significant factor when fighting a disea.... Neuroblastoma is the most common form of solid tumor in children. It is a cancer of the sympathetic nervous system, the network of nerves that regulate u...Burroughs Wellcome fund awards $8.25 million in grants to physician-scientists
...rsity of North Carolina-Chapel Hill The p16INK4 a tumor suppressor in stem cell aging Warren D. Shlomchik, M.D. Yale University Memory T cells for improved immune reconstitution and GVL in allogeneic hematopoietic stem cell transplantation Pradeep Singh, M.D. University of Washington Gallium as a...Mechanisms involved with tumor relapse identified
...mma as one of the signaling proteins involved with tumor relapse. The findings may help researchers devel...an antibody or lymphocytes, or immunization with a tumor vaccine to recognize and eradicate tumor cells. Using a transgenic mouse model of breast cancer,...New cell type identified in cancer development
...in which Gao and his colleagues were investigating tumor growth in mice. They discovered that some of the animals had lymphoma, and that several cell lines from those tumors carried a unique and provocative phenotype, or surface protein signature: They carried neither the Sca-1 or c-kit markers, hallmark...Study reveals how some molecules inhibit growth of lung cancer cells
...concluded that the particular EGFR mutation within tumor cells determines which inhibitor molecules are likely to be able to slow or stop the growth of those cells. "Although structural divergence in the EGFR mutants may complicate efforts to treat the disease, it may also present an advantage in that it...Breakthrough vaccine to treat chemo-resistant ovarian cancer
...eakthrough treatment method uses the patient's own tumor tissues to create a patient-specific vaccine and is combined with chemotherapy delivered directly into the abdominal cavity. Ovarian cancer, one of the hardest cancers to detect in the early stages, is a very complex disease that is often resistan...New drugs for cancer therapy at international conference in Amsterdam
...rowth of tumors or the blood vessels supplying the tumor with nutrients. Many leading cancer institutes from all over the world are represented at the TAT 2007 conference in Amsterdam. In total, about 600 delegates from over 40 countries will gather at the VU University Main Building in a conference org...