Tag: "tumors" at biology news
Other highlights in the November 17 JNCI
...patients who did not receive surgery because their tumors
were inoperable, those who received neoadjuvant ch...fluorouracil, according to a new study. Some solid tumors
may be resistant to cytotoxic drugs because the pH outside the tumor cells is more acidic than that ...
Gene expression profiling aids in ovarian cancer prognosis
...better understanding of the genetic profile of the tumors
of individual patients could help in making a more... Cannistra. "It may also provide insights into why tumors
frequently develop resistance to chemotherapy, and may eventually permit individualized use of targe...
A 'repulsive' protein guides blood vessel development
...s devise methods to prevent blood vessel growth in tumors
selectively an approach to cancer treatment known as anti-angiogenesis. The research team, which included Howard Hughes Medical Institute investigators David D. Ginty and Thomas M. Jessell , published its findings November 18, 2004, in Science E...
Down Syndrome protein reduces tumor growth
...wn syndrome have reduced risk for developing solid tumors
and atherosclerosis," notes Dr. Minami. "DSCR-1 ma...nsible--at least in part--for the reduced risk for tumors
and atherosclerosis in this patient population." This connection between overexpression of DSCR-1 an...
Isotron licenses ORNL cancer treatment technology
... higher. This makes it possible to reach and treat tumors
that previously could be treated only with convent...d cases of prostate cancer, cervical cancer, brain tumors
and melanomas. ...
Finding could improve safety of stem cell transplants
...amide, helps eliminate cells that could later form tumors
called teratomas, researchers say in the Nov. 22 issue of The Journal of Cell Biology. "The body has amazing mechanisms to eliminate cells that are no longer wanted and that if they remain will harm the body by developing into tissues that are n...
Shark cartilage cancer 'cure' shows danger of pseudoscience
...Ostrander's paper details more than 40 examples of tumors
in sharks and related species, dating back to the mid-1800s. In the paper, Ostrander and a team of researchers from the Registry of Tumors in Lower Animals not only dissect what they call the "fallacious arguments" that have successfully convinc...
JCI table of contents, December 1 2004
...pathway have been shown to exist in multiple solid tumors
and leukemia. In the December 1 issue of the Journ... a key regulator of the surveillance of B lymphoid tumors
AUTHOR CONTACT: Veronika Sexl Department of Pharmacology Medical University of Vienna Vienna, Austri...
New breast cancer study shows hormonal therapy not enough
...ith very high levels of estrogen receptor in their tumors
can probably avoid chemotherapy, but those with lower or intermediate levels benefit from it over and above tamoxifen. A second aspect of this study explored the use of various molecular markers measured on the breast tumor to predict the added ...
Encouraging results from validation study of trial of personalized treatment in breast cancer
...ing time to distant metastasis (the development of tumors
in other parts of the body) and overall survival. The statistical analysis was carried out independently of Amsterdam by a statistical team in Belgium, in collaboration with a bioinformatics group in Switzerland. Dr.Piccart said: "While the overal...
Gene therapy reduces skin cancer to sunburn in mouse model
...ncer risk, many XP sufferers eventually succumb to tumors
at an early age. Mice with mutations in the gene Xpa suffer from XP and develop cancerous lesions on their skin within three weeks after UV light exposure. Dr. Errol Friedberg, professor and chair of pathology at UT Southwestern, in collaboration...
Study shows PET/CT imaging can help diagnose and define occult recurrent cancer
...CT was the only test that showed whether recurrent tumors
were indeed present," and since anatomic information was obtained, the type of treatment that should be applied could be determined, she said. "This is clinically important, since no treatment could be planned in these patients without the benefit of...
Researchers discover new gene in colon cancer
...2 inhibitors have been shown to shrink the size of tumors
in mice. Markowitz likens the 15-PGDH gene to a naturally occurring COX-2 inhibitor. (Celebrex, a popular arthritis drug, is also a COX-2 inhibitor.) Markowitz found that 15-PGDH is directly controlled and activated by another gene, called TGF-beta...
New pathway identified in angiogenesis
...en it creates new feeder lines that help cancerous tumors
grow and spread. Investigators in The Ohio Stat...vascular endothelial growth factor), the substance tumors
secrete to signal nearby blood vessels to build connectors to them. "When tumors
reach a certain ...
JCI table of contents, December 15 2004
...telets help cancer invade other tissues Malignant tumors
have the ability to transfer disease from organ to...rectly applied to confined but well-established PC tumors
in mice. These mice were "preconditioned" prior to treatment, meaning that they were subjected to lo...
UCSD bioinformatics researcher studies tumor genome architectures with career award
...ng tumor genomes helps us to understand better how tumors
behave and progress." Pevzner and Raphael have also held discussions about the Tumor Genome Project with UCSD Cancer Center director Dennis Carson, and Richard Kolodner, a member of UCSD's Ludwig Institute for Cancer Research. Both lent their support...
MIT creates new model of cancer syndrome
...ide, the p53 gene is also very commonly mutated in tumors
unrelated to LFS. Mutations in p53 are detected i...because the mice did not develop the wide range of tumors
seen in human LFS patients. In this study, two different mutations in p53 that are commonly fo...
Timing is everything for optimum combined cancer therapy
...n gliomas. Blood vessels in gliomas and many other tumors
are abnormal and do not deliver oxygen to tumor ce...ively pruned some of the immature blood vessels of tumors
and actively recruited pericytes, cells that support a blood vessel, to temporarily stabilize the tu...
Violent ocean motion no magic potion for reefs
...tied to the production of compounds that can cause tumors
in sea turtles and other animals, and research at other institutions has indicated its spread may also be tied to pollution. Before the team was able to study reefs farther up the coast, hurricanes Jeanne and Frances pummeled the region, forcing a t...
Fundamental finding yields insight into stem cells, cancer; opens door to drug discovery
...h could lead to new drugs that block the growth of tumors
by disrupting the beta-arrestin2 protein's normal ...of brain cancer. About one in five childhood brain tumors
are medulloblastomas. In their experiments, the researchers injected zebrafish embryos with a chemic...
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