Tag: "tumors" at biology news

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...ing genetic mutation, they developed twice as many tumors as those with normal IGF2 levels, the researchers ... to earlier events, situations present well before tumors appear," says the study's leader, Andrew Feinberg, M.D., M.P.H., professor of medicine and director ...

New binding target for oncogenic viral protein

...tumors," Dr. Welcker emphasized. "The study of DNA tumors viruses has been an extremely important tool in understanding the cellular pathways that regulate cell division and are disrupted in cancer. Understanding the mechanisms through which these viruses interact with the cellular machinery that regulates ...

Licorice licks herpes virus infection

...ed with Kaposi sarcoma, a disease characterized by tumors in tissues below the surface of the skin, often found in patients with immunodeficiencies like HIV and AIDS. These investigators demonstrate that a compound found in licorice, glycyrrhizic acid (GA), can kill cells that are latently infected with K...

Researchers uncover mutated genes involved in lung cancer; one affects nonsmokers

...is colleagues analyzed tissue samples from primary tumors of 519 patients in the United States, Japan, Taiwa...y that HER2 also is a mutation occurring mainly in tumors of people who never smoked suggests different pathways may be involved in lung cancer formation in s...

Study examines role of EGFR gene mutations in lung cancer development

...agues searched for these mutations in primary lung tumors from patients in Japan, Taiwan, the United States, and Australia. They also examined these mutations in DNA from nonmalignant lung tissue from many of the lung cancer patients and from other epithelial cancer tissues. In lung cancer patients, mutatio...

JCI table of contents March 1, 2005

...ed with Kaposi sarcoma, a disease characterized by tumors in tissues below the surface of the skin, often found in patients with immunodeficiencies like HIV and AIDS. These investigators demonstrate that a compound found in licorice, glycyrrhizic acid (GA), can kill cells that are latently infected with K...

A new 'strategic partner' in cancer development

...lls from the most aggressive and invasive front of tumors and in metastases at adjacent lymph nodes. In an additional surprise finding, the scientists found concentrations of nerve cell bundles containing L1 located next to clusters of colon cancer cells that, as mentioned, boast large amounts of L1 on thei...

MUHC researchers make cancer target breakthrough

...uction in the growth of both colon and lung cancer tumors with inhibition of the gene. The new target gene i...d that the antisense reduced lung and colon cancer tumors in both laboratory-based tissue cultures and in mice. "Discovering that the antisense works in anima...

New tumor-suppressor gene discovered

...genetic defect in their mats gene, then found that tumors no longer developed within this line of flies in i...a fly, a model laboratory species, which developed tumors on their bodies. Lai suspected that these flies had a naturally occurring genetic defect that cause...

Insight into DNA's 'weakest links' may yield clues to cancer biology

...ells, said the researchers. "If you look at solid tumors in humans, you see that the chromosomes of cancer cells exhibit incredible instability," said Thomas Petes, Ph.D., chair of genetics and microbiology at Duke. "Now, we have been able to mimic some of that instability in yeast cells and can begin to a...

New drug shows promise as powerful anticancer agent

... compound, ON01910, is a potent inhibitor of human tumors in a mouse model system and has low toxicity. The results of this study have led to clinical evaluation of this compound in phase I clinical trials. Plk1 is a molecule that plays a key role in driving cell division. High levels of Plk1 have been obse...

Scientists identify molecule that regulates well-known tumor suppressor

...s likely to be involved in the generation of human tumors through negative regulation of the well-known tumo...Dr. Mak. Elevated DJ-1 levels may explain why some tumors without PTEN mutations exhibit enhanced PKB/Akt activity. The authors go on to suggest that DJ-1 may...

Tumor individuality useful for guiding rational chemotherapeutic decisions

...h in tumor cells and how common mutations in human tumors confer drug resistance, and demonstrates that comb...itors to enhance chemosensitivity to paclitaxel in tumors where the H-ras/MAPK pathway is activated may be therapeutically beneficial. These results suggest t...

Temple University researchers develop new targeted cancer therapy

...studies have found higher levels of Plk1 in cancer tumors and in patients with poorer survival rates. When P...ity was blocked, cancer cells could not divide and tumors could not survive. Led by Prem Reddy, Ph.D., professor of biochemistry and director of the Fels In...

X-chromosome tells the tale

... in the testis but that have increased activity in tumors of the testicles, melanoma and other cancers. Over the past few years, the BCM sequencing center and others around the world have concentrated on sequencing the genomes of organisms studied in the laboratory. The future will look more closely at th...

High cholesterol levels accelerate growth of prostate cancer

...te tumors, showing that cholesterol helps prostate tumors survive and grow at the molecular level by alterin... after tumor cells were injected, the incidence of tumors was more than doubled in the mice on high-cholesterol diets, and the tumors were markedly larger in ...

Highlights of chemical society national meeting in San Diego, March 13-17

...e antioxidants in preventing the formation of skin tumors induced by ultraviolet light. In another study, the research team found that black tea, green tea, grape seed and cranberry extracts were all promising antioxidants for fighting skin cancer when applied topically. ( AGFD 65 and AGFD 66 , Monday, Ma...

Neutralizing a protein linked to tumor development

...ty of a class of enzymes that are often mutated in tumors - receptor tyrosine kinases. These receptors, which sit on the cell surface, normally stimulate intracellular pathways that control proliferation and other cellular functions in response to growth factors. In tumors, these receptors often have mutat...

NJIT Presidential Award winner takes stem cell research another step

...tation could help cancer patients who've had large tumors removed from bone, Arinzeh says. In many such surgeries, patients lose their limbs. But if her method of implanting stem cells is shown to induce bone repair, amputation may not be necessary. Stem cells could also help patients suffering from osteopo...

Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells

...entially can be applied to cancer cells from solid tumors as well as hematological malignancies like leukemia." Naviaux looks forward to examining a wider population of cancer cells to validate the method, combining the resources of his Center with Sandia's laser expertise. A project proposal has been file...

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(Date:10/29/2014)... 29, 2014, Beaverton, OR) New research presented ... International Conference in Houston, TX showed for the ... HPV infection in women using a readily available ... study, presented by Dr. Judith A. Smith, Pharm.D., ... and Reproductive Sciences at The University of Texas ...
(Date:10/29/2014)... both genetic and environmental, have been blamed for ... Some, such as a family history of schizophrenia, ... Toxoplasma gondii , a parasite transmitted by ... viewed with skepticism. , A new study by ... at the University of Pennsylvania,s School of Veterinary ...
(Date:10/29/2014)... number of chemicals from household and industrial products are ... bodies. But for most of them, scientists have yet ... taken the first step toward doing that by estimating ... new method is published in the ACS journal ... and colleagues note that the risks to human health ...
Breaking Biology News(10 mins):HPV infections in women eradicated by AHCC, Japanese mushroom extract 2Penn vet professor investigates parasite-schizophrenia connection 2Penn vet professor investigates parasite-schizophrenia connection 3
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