Tag: "tumors" at biology news
Fox Chase Cancer Center researchers look for 'silenced' genes to monitor kidney cancer patients
...entical pattern of hypermethylation in both kidney tumors
and urine collected before surgery. Forty-four of...o 73 who had undergone surgery to remove cancerous tumors
confined to the kidney. At follow-up after surgery, none of the 25 patients had clinical evidence o...
Study reveals dramatic difference between breast cancers in US and Africa
...vidence that nature plays an important role. These tumors
are biologically quite different in ways that make...ave estrogen receptors, only 23 percent of African tumors
did. These tumors
do not depend on estrogen and thus will not respond to drugs, such as tamoxifen, t...
NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses
...r suppressor gene, had a higher risk of developing tumors
in both the small and large intestine. Now, howeve...AIN-76A, also low in calcium and vitamin D) formed tumors
whereas knock-out mice fed with their regular chow (which was enriched with soybean oil) did not. An...
Combination of Lipitor and Celecoxib
...boratory animal models inhibited 95 percent of the tumors
that developed in untreated animals," Reddy said. "When used together, the drugs were most effective at doses substantially lower than when used alone. "Using a combination of low doses of these chemopreventive agents that have differing action may b...
UCF researcher uncovers protein that could stop replication of cancer cells
...nical trials to disrupt the formation of cancerous tumors
by binding with protective proteins....
Researchers find promising cancer-fighting power of synthetic cell-signaling molecule
...olon, ovary, pancreas, brain and blood, and reduce tumors
in three animal studies, new research shows. In ad...h as low-fat dairy products and soybeans, suppress tumors
in mouse models for colon cancer. Encouraged by these findings, Emory University Professor of Chemis...
Biomarkers isolated from saliva successfully predict oral and breast cancer
...for breast cancer and the early detection of other tumors
one day may be as simple as spitting into a collection tube or cup, according to recent studies by UCLA researchers. In one early study based on a risk model, presented here at the 96th Annual Meeting of the American Association for Cancer Research, ...
Readers of genome decipher signatures of cancer patient outcomes
...ish study of genetic samples from 101 colon cancer tumors
revealed a small set of nine genes that indicate g...s previously shown that patients with stage II MSI tumors
had a better prognosis than stage II MSS tumors, and that all stage III patients have similar progno...
Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma
..., about 40 percent of patients with Ewing's family tumors
and 95 percent with metastases die as a result of ...d effective way to treat Ewing's sarcoma and other tumors
in the clinic. "Clinically, Ewing's patients are treated with combination of chemotherapeutic agents...
Turning viruses into allies against cancer
...X -- showed promise of causing necrosis (death) of tumors
cells in most patients. "Tumor necrosis was eviden...rus used in these studies was engineered to attack tumors
cells without harming surrounding healthy tissue. This virus also was further altered to increase it...
Mother's prenatal and lactational diet may protect daughters from breast cancer
...in nursing and after weaning, showed mammary gland tumors
by six months of age. Conversely, fewer than 60 p...s either maternally or post-weaning formed mammary tumors
by the age of eight months. Those exposed to omega-3 fatty acids both maternally and after weaning ...
Fox Chase Cancer Center researchers identify subset of ovarian cancer patients responsive to Iressa
...ay, we'll be able to sequence key genes in ovarian tumors
to identify the women who would be responsive to g...ib. No mutations of the EGFR were detected in the tumors
of the patients who did not respond. "We went back to these samples and analyzed them to see if we ...
New tumor suppressor gene linked to cancer predisposition
...n ARLTS1 is altered, it loses that ability, giving tumors
a chance to establish themselves and grow. To determine the extent to which ARLTS1 appears in various populations, researchers compared tumor tissue or blood samples from 325 patients with different forms of familial or sporadic cases of cancer to th...
Method holds promise in identifying markers of non-metastatic vs. metastatic breast cancer
...ie Montel et al., "Expression profiling of primary tumors
and matched lymphatic and lung metastases in a xen...he problem of irrelevant genetic variability among tumors
derived from different patients. The study, performed in the lab of Dr. David Tarin, used three ce...
The Molecular Profiling Institute, Inc. launches MammaPrint for breast cancer patients
...y cancer diagnostic that analyzes patients' breast tumors
for their individual DNA expression profile. "M...e of the tumor. However, a significant number of tumors
less than one centimeter in diameter are actually high risk. The 70 genes in a woman's tumor anal...
Romond heads up study and reduces breast cancer recurrence
...ysis. Patients with operable breast cancer, whose tumors
over-expressed HER-2, were enrolled in these studi...percent of breast cancers overexpress HER-2. These tumors
tend to grow faster and are generally more likely to recur than tumors
that do not overproduce HER-2...
Pulsating ultrasound enhances gene therapy for tumors
...owerful than standard ultrasound. HIFU can destroy tumors
through long and continuous exposures that raise t...nwu Xie, M.D., the researchers used pulsed-HIFU on tumors
in mice, then immediately injected an easily measurable reporter gene into the vein in their tails. ...
Blocking COX-1 slows tumor growth in mice
...inhibition slowed the growth of epithelial ovarian tumors
in a mouse model of the disease, is surprising, sa...tal cancer. Eighty-five percent of human ovarian tumors
arise from the epithelium or surface layer of tissue that surrounds the ovaries. While the incidence...
Return to normalcy
...this study is a new insight on p53 regulationthose tumors
that show amplified and overexpressed PPM1D may be analogous to those tumors
with amplified and overexpressed MDM2. In both tumor types, p53 may be functionally inactivated and...
Unexpected lock and key mechanism found for the assembly of tumor blood vessels
...othelia of mouse and human blood vessels that feed tumors
such as colon cancer, melanoma and lung cancer. I...cating that the integrin helped in the creation of tumors
"Our study marks the first time this integrin was found to play a key role in angiogenesis," said V...
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