Biologists at Tufts University discover 1 reason why chromosomes break, often leading to cancer
... published in the Aug. 3 journal "Molecular Cell," two molecular biologists have used yeast artificial ch... using yeast chromosomes. "What we did was take two of these regions of predicted high flexibility, plus a region near a cancer cell breakpoint and a co...Success or failure of antidepressant citalopram predicted by gene variation
...cations, said McMahon.Both of the genes consist of two copies each. The 23 percent increase in likelihood of response to citalopram occurred in people who carried the favorable variations in both copies of both of the genes. People with fewer of the favorable variations didnt have as high a response rate...Coelacanth fossil sheds light on fin-to-limb evolution
...ed living fossils, the discovery suggests that the two living groups of close fish relatives of tetrapods (lungfish and coelacanth) are both highly specialized, according to Friedman. Both groups acquired many of the same specializations, but independently of one another. They give this perception that...Neurosciences and music meet in Montreal
... the main themes. Also included in the program are two poster sessions. The conference organizers encourage all members of the Neuromusic Community to participate in the development of the conference program by submitting proposals for symposia on specific topics that actively contribute to the researc...A low expression of MX2 gene exists in the white blood cells of narcoleptics
...lative also has it. It is very rare for more than two people in the same family to have this sleep disorder. It affects the same number of men and women. Those who suspect they might be suffering from narcolepsy, or another sleep disorder, are urged to consult with their primary care doctor or a sle...Marijuana component opens the door for virus that causes Kaposi's sarcoma
...arcoma. These culture cells display many copies of two prominent cannabinoid receptors. Dr. Groopman and ...ding to these receptors, low doses of THC activate two proteins responsible for maintaining a cells internal framework, or cytoskeleton. By altering the cy...COX-2 inhibitors delay pancreatic cancer precursors in mice
...mors. The UCLA researchers divided the mice into two groups one set received a nimesulide-enriched diet for 10 months; the other was offered only regular mouse chow. Their analyses revealed that the nimesulide diet greatly reduced the number of late-stage PanINs in KrasG12D (10 percent of pancreatic d...Phase II study of therapeutic vaccine shows efficacy in patients with metastatic colorectal cancer
...ibodies and killer T cells. It is hoped that these two components of the immune system then migrate to tumors and kill them without harming any normal tissues. In essence, its like turning up your stereo in the hopes that it will attract the police to your neighbors rowdy party, Harrop said. Harr...Einstein researchers' prototype vaccine could provide improved protection against tuberculosis
... of the secA2 mutant TB vaccine could begin within two to three years, says Dr. Porcelli....Progesterone injections do not prevent preterm birth in twin pregnancies
... the same research network is currently working on two other 17-OHPC studies. One involves women with triplets while the other focuses on women with a short cervix. Both groups are considered to have an intermediate risk of preterm birth. Another question for future research, Thorp said, is whether or ...Handicapping tuberculosis may be the way to a better vaccine
...nto normal mice, which they then infected with the two strains of TB. This procedure gives scientists a m... then infected them with an aerosolized form of TB two months later. The results were impressive, said Jacobs. One month after infection, the lungs of mic...ESA announces 2007 award recipients
...idal invertebrate abundance and algal cover on the two island types. W. S. Cooper Award Paul Fine ...cological research paper published within the past two years by a younger researcher (the lead author of the paper must be 40 years of age or younger at th...New grants bolster efforts to generate faster and cheaper tools for DNA sequencing
...veral groups are developing nanopores (holes about two nanometers in diameter) that may be able to recognize individual DNA bases by their electrical or ionic signals to achieve high-accuracy sequencing of individual DNA molecules. This research team seeks to develop molecular wires that are sufficiently...JCI table of contents: August 1, 2007
...in the EGF gene was the cause of hypomagnesemia in two individuals with isolated autosomal recessive renal hypomagnesemia. The mutation caused pro-EGF to be inappropriately localized in kidney cells that control how much magnesium is lost in the urine and how much is retained by the body. This inappropri...U-M researchers find family of 'on switches' that cause prostate cancer
...state cancer. The team discovered that pieces of two chromosomes can trade places with each other and cause two genes to fuse together. The fused genes then override the off switch that keeps cells from growing u...Aggressive therapy best for certain AML patients
...percent of these patients relapsed and died within two years, says first author Susan P. Whitman, a resea... learn whether aggressive therapy provided through two CALGB clinical trials benefits patients with the mutation. It evaluated 238 people aged 18 to 59 wit...First case of successful ovarian tissue transplantation between two, nonidentical sisters
...te and, after a year, doctors were able to recover two mature oocytes from her ovaries and fertilise them to produce two embryos. This first case of a successful transplantation of ovarian tissue between two non-identic...Measuring nectar from eucalypts
... not produce as much nectar as mature trees. The two eucalypt species chosen for research, Spotted Gum Corymbia maculata and Grey Ironbark Eucalyptus paniculata, are of prime importance to nectarfeeding wildlife, the timber industry and beekeepers. Using cranes and cherry-pickers, flowers in forest c...New databases put wings on search for bipolar risk genes
...atabase lets researchers tap into information from two national studies of BD families collected over 20 ...ican Journal of Psychiatry, the database is one of two now available at Hopkins BioinforMOODics web site: http://www.hopkinsmedicine.org/Psychiatry/moods/...High rates of HIV infection documented among young Nepalese girls sex-trafficked to India
...r, and that the risk of HIV infection increased by two percent for every additional month of brothel detention. Historically, there has been little recognition of these young girls in brothels because they are typically hidden from both legal authorities and those working to help and study prostituted ...